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公开(公告)号：US12161413B2
公开(公告)日：2024-12-10
申请号：US17260218
申请日：2019-07-10
Inventor： Lin Ke , Hongwei Liu , Nan Zhang , Jod S Mehta , Yu Chi Liu
IPC: A61B3/107 , A61B5/0507 , G16H20/40 , G16H50/30
Abstract: Methods and systems for analysing a property of a cornea of an eye using terahertz (THz) radiation are provided. The method includes projecting a first THz wave onto a surface of the cornea and detecting a first reflected wave being a reflection of the first THz wave reflected from the surface of the cornea. The method further includes deforming the cornea, projecting a second THz wave onto the surface of the cornea after the deforming and detecting a second reflected wave being a reflection of the second THz wave reflected from the surface of the cornea after the deforming. Finally, the method includes calculating the property of the cornea based on the first reflected wave and the second reflected wave.
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公开(公告)号：US12133687B2
公开(公告)日：2024-11-05
申请号：US17215327
申请日：2021-03-29
Applicant: NIDEK CO., LTD.
Inventor： Michihiro Takii
Abstract: An ophthalmic apparatus includes a first optical system for acquiring information regarding an eye refractive power of a subject eye based on reflection light of measurement light reflected from a fundus of the subject eye, a second optical system for acquiring anterior segment information regarding a shape of an anterior segment of the subject eye, and a calculation controller that acquires an axial length of the subject eye based on an on-surface eye refractive power, which is the eye refractive power on a cross section on which an optical axis of the first optical system is arranged and the anterior segment information regarding the cross section.
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公开(公告)号：US12133686B2
公开(公告)日：2024-11-05
申请号：US16972578
申请日：2019-06-04
Applicant: Cylite Pty Ltd
Inventor： Steven James Frisken , Grant Andrew Frisken , Trevor Bruce Anderson
Abstract: Apparatus and methods are presented for non-contact in-vivo measurement of one or more properties of a cornea or tear film with spatial resolution. In certain embodiments the cornea/tear film is probed at substantially normal incidence with a converging array of beamlets from a multi-wavelength optical source, and the reflected light analysed interferometrically to generate a time sequence of pachymetry maps. Thickness variations arising from differences between the external and intraocular pressure, e.g. from the ocular pulse or externally applied pressure changes, are measured and analysed to obtain information on a biomechanical response of the cornea. In preferred embodiments the time variation in tear film thickness is measured and subtracted to yield normalised pachymetry data for the biomechanical analysis. In certain embodiments the apparatus is configured to measure the dynamics and profile of the tear film, using either converging or substantially parallel arrays of beamlets.
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公开(公告)号：US20240335107A1
公开(公告)日：2024-10-10
申请号：US18291664
申请日：2022-07-02
Applicant: CTAK LLC
Inventor： Peter Hersh , Steven Greenstein , John Gelles
CPC classification number: A61B3/107 , A61F9/00804 , A61F2009/00872 , A61F2009/00882 , A61F2009/00893
Abstract: Devices and methods for the amelioration of ectatic corneal disorders using corneal augmentations derived from corneal tissue are disclosed. The shape of the augmentation is determined using data obtained from mapping of a patient's cornea based on computerized corneal topography and tomography. Factors considered include the maximum keratometry and specific iso-deviation contours. In one embodiment, an augmentation is a corneal inlay, intended for insertion into an intrastromal pocket. In a further embodiment, the augmentation is a corneal onlay, intended to be positioned over a region of the cornea from which the epithelial layer has been removed. The corneal onlay is held in place until the epithelial layer regrows over the augmentation. In a further embodiment, the inlay or onlay augmentation is followed by a post-augmentation, further reshaping of the corneal augmentation. In one embodiment, this further reshaping is photorefractive keratectomy (PRK) surgery.
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5.发明公开公开(公告)号：US20240268659A1
公开(公告)日：2024-08-15
申请号：US18636470
申请日：2024-04-16
Applicant: Alcon Inc.
Inventor： Ashok Burton Tripathi , George Charles Polchin , Maximiliano Ramirez Luna , Patrick Terry , Thomas Paul Riederer
CPC classification number: A61B3/102 , A61B3/08 , A61B3/107 , A61F9/00736 , A61F9/00834 , A61F2009/00846 , A61F2009/00851 , A61F2009/00855
Abstract: A system for guiding an ophthalmic procedure is disclosed. The system includes a housing assembly with a head unit configured to be at least partially directed towards a target site in an eye. An optical coherence tomography (OCT) module and stereoscopic visualization camera are at least partially located in the head unit and configured to obtain a first set and a second set of volumetric data, respectively. A controller is configured to register the first set and second set of volumetric data to create a third set of registered volumetric data. The third set and second set of registered volumetric data are rendered, via a volumetric render module, to a first and second region. The first region and the second region are overlaid to obtain a shared composite view of the target site. The controller is configured to extract structural features and/or enable visualization of the target site.
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Patent Agency Ranking
6.发明授权公开(公告)号：US11986240B2
公开(公告)日：2024-05-21
申请号：US17108481
申请日：2020-12-01
Applicant: ALCON INC.
Inventor： Ashok Burton Tripathi , George Charles Polchin , Maximiliano Ramirez Luna , Patrick Terry , Thomas Paul Riederer
CPC classification number: A61B3/102 , A61B3/08 , A61B3/107 , A61F9/00736 , A61F9/00834 , A61F2009/00846 , A61F2009/00851 , A61F2009/00855
Abstract: A system for guiding an ophthalmic procedure is disclosed. The system includes a housing assembly with a head unit configured to be at least partially directed towards a target site in an eye. An optical coherence tomography (OCT) module and stereoscopic visualization camera are at least partially located in the head unit and configured to obtain a first set and a second set of volumetric data, respectively. A controller is configured to register the first set and second set of volumetric data to create a third set of registered volumetric data. The third set and second set of registered volumetric data are rendered, via a volumetric render module, to a first and second region. The first region and the second region are overlaid to obtain a shared composite view of the target site. The controller is configured to extract structural features and/or enable visualization of the target site.
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公开(公告)号：US20240081640A1
公开(公告)日：2024-03-14
申请号：US18511868
申请日：2023-11-16
Applicant: Johnson & Johnson Surgical Vision, Inc.
Inventor： Charles Scales , Guang-ming Dai , Joshua Young , Jeroen Van Der Donckt , Michael Rademaker , Benjamin Straker , Gilles Vandewiele
CPC classification number: A61B3/107 , A61B3/0025 , A61B34/10 , A61B2034/101
Abstract: Described are implementations of systems and methods for an improved machine learning-based system that incorporates pre-operative and intraoperative measurements captured during surgery, as well as additional patient-specific data, to provide an individualized, highly accurate post-operative manifest refraction prediction. According to some embodiments, a determination engine generates a predictive feature set of one or more predictors associated with diagnostic measurements of one or more eyes and performs a recursive selection operation using one or more combinations within the predictive feature set and one or more models to produce a most predictive subset, the most predictive subset having a highest prediction accuracy among other predictive subsets for post-operative manifest refraction. The determination engine generates a determination model by refining and retraining the one or more models of the recursive selection operation utilizing the most predictive subset.
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公开(公告)号：US20240074654A1
公开(公告)日：2024-03-07
申请号：US18060233
申请日：2022-11-30
Applicant: Morgan State University
Inventor： Shiva Mehravaran
CPC classification number: A61B3/107 , A61B3/0025 , A61B3/102
Abstract: A device and method for early detection of eye disease including a corneal topography device including a camera, such as a rotating Scheimpflug camera, configured to measure the elevation of a patient's two anterior corneas sequentially or simultaneously; a computer processor; and non-transitory computer readable media including computer readable instructions, which, when executed by the computer processor, causes the device to measure and store elevation data at a plurality of points on the patient's anterior corneal surfaces; organize the elevation data for each cornea into a two-dimensional matrix where the center of the cornea is in the center of the data frame, rotate the data for a first eye 180 degrees around the Y axis relative to a second eye, subtract data on each corresponding corneal point, and generate an elevation difference matrix showing the degree of symmetry or asymmetry between the patient's left and right eye corneal topography.
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公开(公告)号：US20240000310A1
公开(公告)日：2024-01-04
申请号：US18226802
申请日：2023-07-27
Applicant: Topcon Corporation
Inventor： Toshihiro MINO , Shuyun YEH , Masashi NAKAJIMA , Yasufumi FUKUMA
CPC classification number: A61B3/1005 , A61B3/0025 , A61B3/107 , A61B3/185 , A61B3/117 , A61B3/102 , A61B3/12 , A61B3/135 , A61B3/0058
Abstract: An ophthalmic information processing apparatus includes an acquisition unit and a normalizer. The acquisition unit is configured to acquire eye shape data or an intraocular distance of an eye of a subject. The normalizer is configured to normalize the eye shape data or the intraocular distance based on body data of the subject or a refractive power of the eye of the subject.
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公开(公告)号：US20230414414A1
公开(公告)日：2023-12-28
申请号：US18464192
申请日：2023-09-08
Applicant: AMO Development, LLC
Inventor： Javier Gonzalez , Bruce Woodley
CPC classification number: A61F9/00825 , A61B3/117 , A61B3/107 , A61B3/102 , A61F9/008 , A61B5/0066
Abstract: Systems and methods automatically locate optical surfaces of an eye and automatically generate surface models of the optical surfaces. A method includes OCT scanning of an eye. Returning portions of a sample beam are processed to locate a point on the optical surface and first locations on the optical surface within a first radial distance of the point. A first surface model of the optical surface is generated based on the location of the point and the first locations. Returning portions of the sample beam are processed so as to detect second locations on the optical surface beyond the first radial distance and within a second radial distance from the point. A second surface model of the optical surface is generated based on the location of the point on the optical surface and the first and second locations on the optical surface.
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