公开(公告)号：US20240341588A1

公开(公告)日：2024-10-17

申请号：US18579998

申请日：2022-08-10

申请人： NANYANG TECHNOLOGICAL UNIVERSITY

发明人： Linbo LIU

IPC分类号： A61B3/10 ,  A61B3/12 ,  G01B9/02091

CPC分类号： A61B3/102 ,  A61B3/1241 ,  G01B9/02091

摘要： Aspects concern an optical coherence tomography (OCT) system for imaging of a sample, comprising: a sample arm for directing light onto the sample, the sample arm comprises sample arm optics comprising a dispersive element to generate an extended source for illuminating the sample: a reference arm: a detector for detecting an interference signal from light that is reflected from the reference arm and light that is back-reflected or back-scattered from the sample; and a scanner for scanning the extended source across the sample along a fast axis and a slow axis such that a plurality of partial-spectrum frames is obtained at the detector: wherein the dispersive element is orientable such that the extended source is disposed at a non-zero angle to the fast axis.

公开(公告)号：US12112480B2

公开(公告)日：2024-10-08

申请号：US18107358

申请日：2023-02-08

申请人： Translatum Medicus, Inc.

发明人： Shelley Romayne Boyd ,  Natalie Pankova

IPC分类号： G06T7/00 ,  A61B3/024 ,  A61B3/028 ,  A61B3/10 ,  A61B3/12 ,  A61B3/14 ,  A61B5/00 ,  A61B5/398

CPC分类号： G06T7/0014 ,  A61B3/024 ,  A61B3/028 ,  A61B3/102 ,  A61B3/1025 ,  A61B3/12 ,  A61B3/14 ,  A61B5/0013 ,  A61B5/398 ,  G06T2207/10048 ,  G06T2207/10064 ,  G06T2207/10101 ,  G06T2207/30041

摘要： Disclosed herein are computer systems for, in part, image processing. Also disclosed herein are systems for processing ocular images of multiple imaging modalities to detect ocular diseases. Also disclosed herein are method comprising systems as described herein.

公开(公告)号：US20240324873A1

公开(公告)日：2024-10-03

申请号：US18621342

申请日：2024-03-29

申请人： Optos plc

发明人： Margaret Catherine Normand ,  Miguel Angel Preciado

IPC分类号： A61B3/10 ,  A61B3/12 ,  G06T5/80

CPC分类号： A61B3/102 ,  A61B3/1225 ,  G06T5/80 ,  G06T2207/10101 ,  G06T2207/30041

摘要： A line-field Fourier-domain optical coherence tomography, OCT, imaging system, comprising: a curved mirror, and a scanning element at a first focus of the mirror which scans, via the mirror, a line of light across an object at a second focus of the mirror, and receives, via the mirror, light scattered by the object and aberrated by the mirror to form an aberrated line of light; a photodetector array; an interferometer which projects an interference line of light resulting from an interference between a reference light and the aberrated line of light onto the photodetector array. The OCT imaging system generates OCT data based on the interference line of light detected by the photodetector array, and corrects the OCT data using phase information in the OCT data such that the corrected OCT data has less optical aberration than the OCT data.

公开(公告)号：US20240323524A1

公开(公告)日：2024-09-26

申请号：US18615710

申请日：2024-03-25

申请人： Medimaging Integrated Solution, Inc.

发明人： Jia-Pu Syu ,  CHIEN-CHI HUANG ,  Yu-Tsung Lee ,  Hung-Chin Chen

IPC分类号： H04N23/67 ,  A61B3/10 ,  A61B3/12 ,  A61B3/14 ,  G06T7/00

CPC分类号： H04N23/67 ,  A61B3/102 ,  A61B3/12 ,  A61B3/14 ,  G06T7/0014 ,  G06T2207/10101 ,  G06T2207/30041 ,  G06T2207/30204

摘要： An optical coherence tomography image system and an autofocus method thereof are provided. The autofocus method captures a reference chart at a plurality of preset diopter positions, receives an interference signal generated by the reflection of a light beam projected onto an eyeball, and analyzes the reference chart and the interference signal to obtain an analysis value and a corresponding diopter. The method compares the plurality of analysis values to obtain one meeting the standard condition as the target analysis value. According to the target analysis value and the corresponding diopter, the focusing driving device is controlled to move to the position corresponding to the diopter to complete autofocusing. Therefore, the present invention can reduce the time of autofocusing, obtain a higher shooting success rate, provide better user experience, and use a lower-order computing device to reduce costs.

公开(公告)号：US20240315554A1

公开(公告)日：2024-09-26

申请号：US18734253

申请日：2024-06-05

申请人： University of Iowa Research Foundation ,  United States Government as Represented by the Department of Veterans Affairs

发明人： Michael D. Abramoff ,  Meindert Niemeijer ,  Xiayu Xu ,  Milan Sonka ,  Joseph M. Reinhardt

IPC分类号： A61B3/12 ,  A61B3/00

CPC分类号： A61B3/12 ,  A61B3/0016 ,  A61B3/0058 ,  A61B3/1225

摘要： The methods and systems provided can automatically determine an Arteriolar-to-Venular diameter Ratio, AVR, in blood vessels, such as retinal blood vessels and other blood vessels in vertebrates. The AVR is an important predictor of increases in the risk for stroke, cerebral atrophy, cognitive decline, and myocardial infarct.

公开(公告)号：US20240306908A1

公开(公告)日：2024-09-19

申请号：US18577161

申请日：2022-07-08

申请人： CEDARS-SINAI MEDICAL CENTER ,  THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

发明人： Maya Koronyo ,  Yosef Koronyo ,  Keith L. Black ,  Nazanin Mirzaei ,  Liang Gao

IPC分类号： A61B3/10 ,  A61B3/12 ,  G16H30/20 ,  G16H50/20

CPC分类号： A61B3/102 ,  A61B3/12 ,  G16H30/20 ,  G16H50/20

摘要： The present invention describes systems and method for the detection, diagnosis and monitoring of cognitive impairment and Alzheimer's disease. In one example, an integrated system comprising a full-field Fourier domain optical coherence tomography and an image mapping spectrometry is used for generating spectrally resolved volumetric images at wavelengths that show difference in spectral signatures of normal cells compared to spectral signatures of amyloid beta and pTau deposits, and also image inner retinal layers where amyloid beta and pTau deposits may aggregate.

公开(公告)号：US20240306906A1

公开(公告)日：2024-09-19

申请号：US18280313

申请日：2022-03-10

申请人： KOWA COMPANY, LTD.

发明人： Takuya HARA

IPC分类号： A61B3/00 ,  A61B3/12

CPC分类号： A61B3/0075 ,  A61B3/12

摘要： An ophthalmic device (1) of the present invention has an optical head (2) including a light projection optical system (21) that projects light onto a subject eye (E), a light reception optical system (22) that receives light from the subject eye (E), and a fixation lamp (23) for guiding a line-of-sight direction of the subject eye (E), and a turning drive unit that turns the optical head (2) in a horizontal direction while maintaining positional relationships between the light projection optical system (21), the light reception optical system (22), and the fixation lamp (23). The turning drive unit is composed of a rotational drive unit (4) that rotates the optical head (2) in the horizontal direction and a horizontal drive unit (3) that moves the optical head (2) in the horizontal direction.

公开(公告)号：US20240277296A1

公开(公告)日：2024-08-22

申请号：US18130368

申请日：2023-04-03

申请人： VISUWORKS Inc.

发明人： Ik Hee RYU ,  Jin Kuk KIM ,  Tae Keun YOO

IPC分类号： A61B5/00 ,  A61B3/00 ,  A61B3/103 ,  A61B3/12 ,  A61B3/14

CPC分类号： A61B5/7275 ,  A61B3/0025 ,  A61B3/103 ,  A61B3/12 ,  A61B3/14

摘要： An electronic device for predicting myopia regression, which includes a memory and a processor connected with the memory to execute instructions included in the memory. The processor collects first target data of a subject and second target data of the subject, extracts a first result value as output data for a first machine learning model by using the first target data as input data for the first machine learning model, and determines whether there is a possibility of myopia regression of the subject based on the first result value.

公开(公告)号：US20240277224A1

公开(公告)日：2024-08-22

申请号：US18540661

申请日：2023-12-14

申请人： Medimaging Integrated Solution, Inc.

发明人： Chu-Ming Cheng ,  Wei Ting Tseng ,  LI-REN CAI ,  Hung-Chin Chen ,  CHIEN-CHI HUANG ,  Yung-En Kuo ,  PEI-SHENG WU

IPC分类号： A61B3/10 ,  A61B3/00 ,  A61B3/12 ,  A61B3/14 ,  G06T5/40 ,  G06T5/70 ,  G06T7/13

CPC分类号： A61B3/102 ,  A61B3/0058 ,  A61B3/1225 ,  A61B3/14 ,  G06T5/40 ,  G06T5/70 ,  G06T7/13 ,  G06T2207/10101 ,  G06T2207/30041

摘要： The invention provides an optical coherence tomography self-testing system, an optical coherence tomography method and an ocular disease monitoring system. The optical coherence tomography self-testing system comprises a camera device, an external display module and a communication module. The camera device includes an image-capturing module and a processing module. The image-capturing module captures a plurality of ocular images. The processing module is connected to the image-capturing module, and the processing module determines whether a position offset value between the pupil center position of a tested eyeball and an optical axis of the image-capturing module is within a preset error range. If the position offset value is within the preset error range, the plurality of ocular images is stored as a plurality of displayed images. The external display module displays one of the plurality of displayed images and a status light after the image-capturing module has completed image capturing.

公开(公告)号：US12067655B2

公开(公告)日：2024-08-20

申请号：US17576054

申请日：2022-01-14

申请人： NIKON CORPORATION

发明人： Yasushi Tanabe ,  Daishi Tanaka ,  Makoto Ishida ,  Mariko Mukai

IPC分类号： G06T11/60 ,  A61B3/10 ,  A61B3/12 ,  A61B5/00 ,  G06T19/00

CPC分类号： G06T11/60 ,  A61B3/102 ,  A61B3/12 ,  A61B5/0035 ,  A61B5/004 ,  G06T19/00 ,  G06T2210/41

摘要： An image processing method includes acquiring a three-dimensional image of a subject eye and a two-dimensional image of the subject eye, specifying a first reference point in the three-dimensional image, specifying a second reference point in the two-dimensional image, and generating a superposed image. In the superposed image, the first reference point in the three-dimensional image is coordinated with the second reference point in the two-dimensional image and the two-dimensional image is superposed with at least a portion of the three-dimensional image.