公开(公告)号：US20130140267A1

公开(公告)日：2013-06-06

申请号：US13752959

申请日：2013-01-29

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Kazuhiko SHIOMITSU ,  Hiroshi SUGIMURA ,  Toshiaki KUROSU ,  Gaku SUZUKI ,  Takao TOMONO

IPC: B44C1/22

CPC classification number: B44C1/227 ,  A61M37/0015 ,  A61M2037/003 ,  A61M2037/0038 ,  A61M2037/0046 ,  A61M2037/0053 ,  B29C33/42 ,  B81B2201/055 ,  B81C1/00111 ,  B81C2201/0198

Abstract: The invention discloses a method of manufacturing a microneedle including the steps of forming an island etching mask having thickness distribution on a substrate, and processing the substrate into a needle by taking advantage of a difference in etching rates between the etching mask and the substrate. The invention enables to readily control a point angle and height of the manufactured needle.

Abstract translation: 本发明公开了一种制造微针的方法，包括以下步骤：在衬底上形成具有厚度分布的岛蚀刻掩模，并通过利用蚀刻掩模和衬底之间的蚀刻速率差来将衬底处理成针。 本发明能够容易地控制所制造的针的点角度和高度。

公开(公告)号：US20150217101A1

公开(公告)日：2015-08-06

申请号：US14689541

申请日：2015-04-17

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Tomoya SUMIDA ,  Yumiko YAMADA ,  Masaki KONO ,  Yoshihiro KODAMA ,  Kazuhiko SHIOMITSU

IPC: A61M37/00

CPC classification number: A61M37/0015 ,  A61B17/205 ,  A61M2037/0023 ,  A61M2037/003 ,  F04C2270/0421

Abstract: An operation tool for a fluid injector includes a selective movement mechanism which moves the fluid injector between a first protruding position and a second protruding position in a housing of an outer cylinder. When the fluid injector is at the first protruding position, microneedles of a multi-microneedle device are protruded out to a first distance from the first open end. When the fluid injector is at the second protruding position to discharge a fluid via the microneedles, the microneedles are protruded out to a second distance from the first open end, which is shorter than the first distance. The selective movement mechanism includes a rotational-linear movement conversion mechanism which moves the fluid injector between the first and second protruding positions along a longitudinal center line of the outer cylinder based on a direction and an amount of rotation of the outer cylinder relative to the fluid injector.

Abstract translation: 用于流体注射器的操作工具包括选择运动机构，该选择运动机构使流体注射器在外筒的壳体中的第一突出位置和第二突出位置之间移动。 当流体注射器处于第一突出位置时，多微针装置的微针从第一开口端突出到第一距离。 当流体注射器处于第二突出位置以通过微针排出流体时，微针从与第一距离短的第一开口端突出到第二距离。 选择运动机构包括旋转线性运动转换机构，其基于外筒相对于流体的方向和旋转量沿着外筒的纵向中心线在第一和第二突出位置之间移动流体喷射器 注射器。

公开(公告)号：US20170120027A1

公开(公告)日：2017-05-04

申请号：US15404345

申请日：2017-01-12

Applicant: TOPPAN PRINTING CO., LTD.

Inventor： Kazuhiko SHIOMITSU

IPC: A61M37/00

CPC classification number: A61M37/0015 ,  A61M2037/0023 ,  A61M2037/0053

Abstract: A microneedle including a substrate having a first surface and a second surface opposite to the first surface, at least one piercing projection projecting from the first surface of the substrate and being surrounded by an outer peripheral region of the substrate when viewed in a direction perpendicular to the first surface, and surface-defining structures positioned in the outer peripheral region and including three or more surface-defining structures each having a surface-defining section which is one of a surface-defining projection and a surface-defining recess. The surface-defining projection protrudes from the first surface and has a tip which serves as the surface-defining section, the surface-defining recess is recessed from the first surface and has a bottom serving as the surface-defining section, and the piercing projection has a tip that extends beyond a plane including the surface-defining sections of three surface-defining structures among the surface-defining structures.