公开(公告)号：US20110060136A1

公开(公告)日：2011-03-10

申请号：US12878755

申请日：2010-09-09

申请人： Tadashi MATSUNAGA ,  Tsuyoshi TANAKA ,  Keiichi HATAKEYAMA ,  Takeo TANAAMI ,  Hitoshi WAKE ,  Tomoyuki TAGUCHI ,  Takeyuki MOGI

发明人： Tadashi MATSUNAGA ,  Tsuyoshi TANAKA ,  Keiichi HATAKEYAMA ,  Takeo TANAAMI ,  Hitoshi WAKE ,  Tomoyuki TAGUCHI ,  Takeyuki MOGI

IPC分类号： C07H1/06 ,  H01F1/00

CPC分类号： B82Y25/00 ,  B22F2304/054 ,  B22F2998/00 ,  H01F1/0054 ,  B22F1/02 ,  B22F1/0018

摘要： Dendrimer-coated magnetic fine particles comprise magnetic fine particles, a lipid bilayer covering a surface of individual magnetic fine particles, and a dendrimer bound to an outer layer of the lipid bilayer. With the dendrimer-coated magnetic fine particles, the dendrimer is positively charged are brought into contact with a nucleic acid-containing solution to adsorb the nucleic acid on the dendrimer, while the nucleic acid-adsorbed fine particles are collected by magnetic force to recover the nucleic acid from the solution.

摘要翻译： 树枝状聚合物包覆的磁性细颗粒包括磁性细颗粒，覆盖单个磁性细颗粒的表面的脂质双层和与脂质双层的外层结合的树枝状聚合物。 对于树枝状大分子的磁性细颗粒，带正电的树枝状聚合物与含核酸的溶液接触以将核酸吸附在树状聚合物上，同时通过磁力收集核酸吸附的微粒以回收 来自该溶液的核酸。