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37 条记录 (耗时 0.024 秒)

    Antipathogen assembly
    4.
    发明授权
    Antipathogen assembly 失效
    抗病原体组装

    公开(公告)号：US5417675A

    公开(公告)日：1995-05-23

    申请号：US818209

    申请日：1992-01-08

    申请人： Tyler Watanabe ,  Su I. Yum ,  Fun S. Lee ,  Ivan W. Chin

    发明人： Tyler Watanabe ,  Su I. Yum ,  Fun S. Lee ,  Ivan W. Chin

    IPC分类号： A61F5/441 ,  A61M1/00

    CPC分类号： A61F5/441 ,  A61M1/0096

    摘要： The invention disclosed and claimed an apparatus that relates to a delivery system comprising a biocide, with the delivery system designed and shaped for passages through the exit port of a urine container into the container. The invention disclosed and claim pertains also to a method of preventing infection in a patient by using the apparatus connected to a patient through a catheter.

    摘要翻译： 本发明公开并要求了一种涉及包括杀生物剂的输送系统的装置，该输送系统被设计和成形，用于通过尿液容器的出口进入容器。 本发明的公开和权利要求还涉及通过使用通过导管连接到患者的装置来预防患者感染的方法。

    Transdermal administration of oxybutynin
    5.
    发明授权
    Transdermal administration of oxybutynin 失效
    透皮给药奥昔布宁

    公开(公告)号：US5411740A

    公开(公告)日：1995-05-02

    申请号：US193661

    申请日：1994-02-08

    申请人： Eun S. Lee ,  Diane E. Nedberge ,  Su I. Yum

    发明人： Eun S. Lee ,  Diane E. Nedberge ,  Su I. Yum

    IPC分类号： A61K9/00 ,  A61K9/70 ,  A61K31/135 ,  A61K31/215 ,  A61K31/216 ,  A61K47/10 ,  A61K47/14 ,  A61K47/34 ,  A61P13/02 ,  A61P15/00 ,  A61P25/00 ,  A61F13/02

    CPC分类号： A61K9/7053 ,  A61K31/215 ,  A61K31/216 ,  A61K47/14 ,  A61K9/0014 ,  A61K9/7084 ,  Y10S514/946

    摘要： The present invention is directed to the transdermal administration of oxybutynin together with a suitable permeation enhancer. The invention includes a transdermal drug delivery device comprising a matrix adapted to be placed in oxybutynin- and permeation enhancer-transmitting relation with the skin site. The matrix contains sufficient amounts of a permeation enhancer and of oxybutynin, in combination, to continuously administer to the skin for a predetermined period of time the oxybutynin to provide an effective therapeutic result. The invention is also directed to a method for the transdermal administration of a therapeutically effective amount of oxybutynin together with a skin permeation-enhancing amount of a suitable permeation enhancer.

    摘要翻译： 本发明涉及奥昔布宁与合适的渗透增强剂的透皮给药。 本发明包括透皮药物递送装置，其包含适于与皮肤部位置于奥昔布宁和渗透增强剂 - 传递关系中的基质。 基质含有足量的渗透促进剂和奥昔布宁组合，以持续给予皮肤预定的时间，奥昔布宁提供有效的治疗结果。 本发明还涉及用于透皮给药治疗有效量的奥昔布宁以及皮肤渗透增强剂量的合适的渗透增强剂的方法。

    Transdermal drug delivery device
    8.
    发明授权
    Transdermal drug delivery device 失效
    透皮给药装置

    公开(公告)号：US4781924A

    公开(公告)日：1988-11-01

    申请号：US118577

    申请日：1987-11-09

    申请人： Eun S. Lee ,  Su I. Yum

    发明人： Eun S. Lee ,  Su I. Yum

    IPC分类号： A61K9/70 ,  A61M37/00 ,  A61F13/00

    CPC分类号： A61K9/7084

    摘要： A diffusional drug delivery device is described which can provide for stability of the adhesive and system components, elimination of the initial burst of drug and hence irritation, and to provide for delayed onset of therapeutic effect along with delivery of a therapeutic agent at an optimum rate. The therapeutic agent in a first form which is suitable for storage, and the anhydrous activating means are inert when in an anhydrous environment. Moisture activates the system whereby the activating means provides an acidic or basic solution and the first form of the therapeutic agent is converted to a second form which is suitable for absorption through the skin or mucosa.

    Transdermal drug delivery device
    9.
    发明授权
    Transdermal drug delivery device 失效
    透皮给药装置

    公开(公告)号：US4917895A

    公开(公告)日：1990-04-17

    申请号：US219115

    申请日：1988-07-14

    申请人： Eun S. Lee ,  David Edgren ,  Su I. Yum

    发明人： Eun S. Lee ,  David Edgren ,  Su I. Yum

    IPC分类号： A61K9/70 ,  A61L31/00

    CPC分类号： A61K9/703 ,  A61K9/7053 ,  A61K9/7084

    摘要： A diffusional drug delivery device is described which can provide shelf life stability of the system components, elimination of the initial burst of drug and hence irritation, delayed onset of therapeutic effect and delivery of a therapeutic agent at an optimum rate. A metal layer and an activating means are inert when dry. Moisture activates the system whereby the activating means provides release of an eroding agent which erodes the metal layer through which the therapeutic agent diffuses and is subsequently delivered.

    摘要翻译： 描述了扩散药物递送装置，其可以提供系统组件的保质期稳定性，消除药物的初始爆发，因此刺激，治疗效果的延迟开始和治疗剂以最佳速率递送。 当干燥时，金属层和激活装置是惰性的。 水分激活系统，由此激活装置提供侵蚀剂的释放，侵蚀剂侵蚀治疗剂扩散并随后递送的金属层。

    Transdermal drug delivery device
    10.
    发明授权
    Transdermal drug delivery device 失效
    透皮给药装置

    公开(公告)号：US4837027A

    公开(公告)日：1989-06-06

    申请号：US230211

    申请日：1988-08-09

    申请人： Eun S. Lee ,  Su I. Yum

    发明人： Eun S. Lee ,  Su I. Yum

    IPC分类号： A61K9/70

    CPC分类号： A61K9/7053 ,  A61K9/7084

    摘要： A diffusional drug delivery device is described which can provide for stability of the adhesive and system components, elimination of the initial burst of drug and hence irritation, and to provide for delayed onset of therapeutic effect along with delivery of a therapeutic agent at an optimum rate. The therapeutic agent in a first form which is suitable for storage, and the anhydrous activating means are inert when in an anhydrous environment. Moisture activates the system whereby the activating means provides an acidic or basic solution and the first form of the therapeutic agent is converted to a second form which is suitable for absorption through the skin or mucosa.

    摘要翻译： 描述了扩散药物递送装置，其可以提供粘合剂和系统组分的稳定性，消除药物的初始爆发并因此刺激，并且提供治疗效果的延迟开始以及以最佳速率递送治疗剂 。 适于储存的第一种形式的治疗剂和无水活化装置在无水环境中是惰性的。 水分激活系统，由此激活装置提供酸性或碱性溶液，并且将第一形式的治疗剂转化为适合于通过皮肤或粘膜吸收的第二种形式。