公开(公告)号：US11957762B2

公开(公告)日：2024-04-16

申请号：US15577998

申请日：2016-05-27

Applicant: University of Utah Research Foundation

Inventor： Mingnan Chen ,  Hyung Jin Cho ,  Peng Wang ,  Shuyun Dong ,  Peng Zhao

IPC: A61K47/64 ,  A61K31/337 ,  A61K31/35 ,  A61K38/00 ,  A61K39/00 ,  A61P35/00 ,  A61P35/04 ,  C07K14/77 ,  C07K14/78

CPC classification number: A61K47/6435 ,  A61K31/337 ,  A61K31/35 ,  A61K39/0005 ,  A61K47/64 ,  A61P35/00 ,  A61P35/04 ,  C07K14/77 ,  C07K14/78 ,  A61K38/00 ,  A61K2039/6031 ,  C07K2319/00

Abstract: Disclosed herein, are recombinant polypeptides comprising one or more homologous amino acid repeats; and, non-immunogenic bioconjugates comprising recombinant polypeptides comprising one or more homologous amino acid repeats and one or more therapeutic agents. Also, disclosed herein are pharmaceutical compositions including the recombinant polypeptides; and methods of administering the recombinant polypeptides to patients for the treatment of cancer or infections.

公开(公告)号：US20180289830A1

公开(公告)日：2018-10-11

申请号：US15577998

申请日：2016-05-27

Applicant: University of Utah Research Foundation

Inventor： Mingnan Chen ,  Hyung Jin Cho ,  Peng Wang ,  Shuyun Dong ,  Peng Zhao

IPC: A61K47/64 ,  C07K14/78 ,  A61K31/35 ,  A61K31/337 ,  C07K14/77 ,  A61P35/00 ,  A61P35/04 ,  A61K39/00

Abstract: Disclosed herein, are recombinant polypeptides comprising one or more homologous amino acid repeats; and, non-immunogenic bioconjugates comprising recombinant polypeptides comprising one or more homologous amino acid repeats and one or more therapeutic agents. Also, disclosed herein are pharmaceutical compositions including the recombinant polypeptides; and methods of administering the recombinant polypeptides to patients for the treatment of cancer or infections.