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公开(公告)号：US20150306275A1
公开(公告)日：2015-10-29
申请号：US14713307
申请日：2015-05-15
发明人： Jeffrey M. Gross , Steve Peckham , Jeffrey L. Scifert , Jeffrey Badura , Nelson Scarborough , Scott Vickers
IPC分类号： A61L27/22
CPC分类号： A61L27/227 , A61K38/00 , A61L27/46 , A61L27/48 , A61L27/54 , A61L2300/414 , A61L2300/602 , A61L2400/18 , A61L2420/02 , A61L2430/02
摘要： In certain described embodiments, implantable medical materials comprise a scaffolding material, a liquid organic binder, and entrapped calcium-containing particles. The medical materials can incorporate an osteoinductive factor such as a protein. The scaffolding material can bind the factor. In additional described embodiments, implantable medical materials include an osteoconductive scaffolding material, an incorporated osteoinductive factor, and a biodegradable barrier material effective to delay release of the factor from the scaffolding material. The scaffolding material can bind the factor. Also described a methods for preparing and implanting the described medical materials.
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公开(公告)号：US10441679B2
公开(公告)日：2019-10-15
申请号：US16128784
申请日：2018-09-12
发明人： Jeffrey M. Gross , Steve Peckham , Jeffrey L. Scifert , Jeffrey Badura , Nelson Scarborough , Scott Vickers
摘要： In certain described embodiments, implantable medical materials comprise a scaffolding material, a liquid organic binder, and entrapped calcium-containing particles. The medical materials can incorporate an osteoinductive factor such as a protein. The scaffolding material can bind the factor. In additional described embodiments, implantable medical materials include an osteoconductive scaffolding material, an incorporated osteoinductive factor, and a biodegradable barrier material effective to delay release of the factor from the scaffolding material. The scaffolding material can bind the factor. Also described a methods for preparing and implanting the described medical materials.
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公开(公告)号：US20190009001A1
公开(公告)日：2019-01-10
申请号：US16128784
申请日：2018-09-12
发明人： Jeffrey M. Gross , Steve Peckham , Jeffrey L. Scifert , Jeffrey Badura , Nelson Scarborough , Scott Vickers
CPC分类号： A61L27/227 , A61K38/00 , A61L27/46 , A61L27/48 , A61L27/54 , A61L2300/414 , A61L2300/602 , A61L2400/18 , A61L2420/02 , A61L2430/02
摘要： In certain described embodiments, implantable medical materials comprise a scaffolding material, a liquid organic binder, and entrapped calcium-containing particles. The medical materials can incorporate an osteoinductive factor such as a protein. The scaffolding material can bind the factor. In additional described embodiments, implantable medical materials include an osteoconductive scaffolding material, an incorporated osteoinductive factor, and a biodegradable barrier material effective to delay release of the factor from the scaffolding material. The scaffolding material can bind the factor. Also described a methods for preparing and implanting the described medical materials.
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公开(公告)号：US10080819B2
公开(公告)日：2018-09-25
申请号：US14713307
申请日：2015-05-15
发明人： Jeffrey M. Gross , Steve Peckham , Jeffrey L. Scifert , Jeffrey Badura , Nelson Scarborough , Scott Vickers
CPC分类号： A61L27/227 , A61K38/00 , A61L27/46 , A61L27/48 , A61L27/54 , A61L2300/414 , A61L2300/602 , A61L2400/18 , A61L2420/02 , A61L2430/02
摘要： In certain described embodiments, implantable medical materials comprise a scaffolding material, a liquid organic binder, and entrapped calcium-containing particles. The medical materials can incorporate an osteoinductive factor such as a protein. The scaffolding material can bind the factor. In additional described embodiments, implantable medical materials include an osteoconductive scaffolding material, an incorporated osteoinductive factor, and a biodegradable barrier material effective to delay release of the factor from the scaffolding material. The scaffolding material can bind the factor. Also described a methods for preparing and implanting the described medical materials.
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