公开(公告)号：US20240350258A1

公开(公告)日：2024-10-24

申请号：US18682622

申请日：2021-08-10

Applicant: VSY BIYOTEKNOLOJI VE ILAC SANAYI ANONIM SIRKETI

Inventor： Faruk OYTUN

IPC: A61F2/16 ,  A61L27/34

CPC classification number: A61F2/1675 ,  A61F2/1678 ,  A61L27/34 ,  A61L2400/10 ,  A61L2420/02 ,  A61L2420/08 ,  A61L2430/16

Abstract: Spin-assisted layer-by-layer polymer coatings are used as the inner surface coating material for intraocular lens cartridges and facilitate the implantation of intraocular lenses.

公开(公告)号：US12121628B2

公开(公告)日：2024-10-22

申请号：US16713168

申请日：2019-12-13

Applicant: INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY

Inventor： Ho Jun Song ,  Yeong Joon Park ,  Hye Won Lee ,  Moon Jin Hwang ,  Hyun Joo Moon ,  Woon Young Lee

IPC: A61L27/06 ,  B82Y5/00 ,  B82Y40/00

CPC classification number: A61L27/06 ,  A61L2400/18 ,  A61L2420/02 ,  A61L2430/02 ,  B82Y5/00 ,  B82Y40/00

Abstract: The present disclosure provides a method for surface modification of a titanium implant material and a titanium implant obtained by the method for surface treatments. A titanium implant according to one embodiment of the present disclosure has high bond strength between implant and bone and its corrosion resistance.

公开(公告)号：US12109332B2

公开(公告)日：2024-10-08

申请号：US18386896

申请日：2023-11-03

Applicant: The Regents of the University of California ,  Silq Technologies Corporation

Inventor： Brian T. McVerry ,  Ethan Rao ,  Richard B. Kaner ,  Na He

IPC: A61L31/00 ,  A61L29/08 ,  C08F220/30 ,  C08F220/34 ,  C08F220/38 ,  C08F293/00 ,  C09D5/00 ,  C09D153/00

CPC classification number: A61L31/00 ,  A61L29/085 ,  C08F220/30 ,  C08F220/34 ,  C08F220/382 ,  C08F293/005 ,  C09D5/00 ,  C09D153/00 ,  A61L2420/02 ,  C08F2438/01

Abstract: Disclosed herein are compositions to use in biofouling-resistant coatings, biofouling-resistant coatings, methods of making biofouling-resistant coatings, biofouling-resistant devices, and methods of making biofouling-resistant devices.

公开(公告)号：US12109331B2

公开(公告)日：2024-10-08

申请号：US17467637

申请日：2021-09-07

Applicant: OLYMPUS CORPORATION

Inventor： Takashi Magara

IPC: A61L29/04 ,  A61B1/005 ,  A61L29/16 ,  C08L27/18 ,  C08L27/20 ,  C08L63/00

CPC classification number: A61L29/16 ,  A61B1/005 ,  A61L29/049 ,  A61L2420/02 ,  C08L27/18 ,  C08L27/20 ,  C08L63/00

Abstract: A medical device includes a resin base including one or more than one material selected from a group consisted by an ethylene propylene resin containing fluorine, a styrene resin containing fluorine, an olefin resin containing fluorine, a vinyl chloride resin containing fluorine, a polyester resin containing fluorine, a polyurethane resin containing fluorine, and a nylon resin containing fluorine; an underlayer formed on the resin base, the underlayer including an oxazolidone ring; and an epoxy resin layer formed on the underlayer.

公开(公告)号：US20240325605A1

公开(公告)日：2024-10-03

申请号：US18623287

申请日：2024-04-01

Applicant: BVW Holding AG

Inventor： Lukas Bluecher ,  Michael Milbocker

IPC: A61L27/50 ,  A61L27/36 ,  A61L27/38 ,  G03F7/20

CPC classification number: A61L27/50 ,  A61L27/3633 ,  A61L27/3886 ,  A61L2420/02 ,  G03F7/2002

Abstract: Provided herein is a tissue scaffold that may include microstructure patterns on one or more surfaces that can modify the physical properties of the tissue scaffold. The microstructure patterns may be cell-directing across a larger spatial range than the prior art which uses chemically modified substrates. The present disclosure further includes tissue scaffold configured such that cells may infiltrate the tissue scaffold by responding to patterns of surface energy gradients on the tissue scaffold and the cells may not be constrained into patterns by physical means. As the cells proliferate, they associate and orient in response to long-range patterns to form confluent monolayers of cells while constructing functional macro-structure across the tissue scaffold surface.

公开(公告)号：US12104136B2

公开(公告)日：2024-10-01

申请号：US17326041

申请日：2021-05-20

Applicant: Merit Medical Ireland Limited

Inventor： Martin Moran ,  Emmanouil Kasotakis

IPC: C10M107/44 ,  A61L29/08 ,  A61M25/00 ,  C10M107/28 ,  C10N40/00 ,  C10N50/00

CPC classification number: C10M107/44 ,  A61L29/085 ,  A61M25/0045 ,  C10M107/28 ,  A61L2400/10 ,  A61L2420/02 ,  A61L2420/06 ,  A61L2420/08 ,  A61M2025/0046 ,  C10M2209/0845 ,  C10M2209/0863 ,  C10M2217/0453 ,  C10N2040/50 ,  C10N2050/023

Abstract: Coatings for medical devices having selectable levels of durability and lubricity are disclosed. The coatings include polymeric material components, the characteristics and relative amounts of which can be selected to provide target levels of durability and lubricity. Methods of making the coatings for medical devices are also disclosed.

公开(公告)号：US12102547B2

公开(公告)日：2024-10-01

申请号：US16865242

申请日：2020-05-01

Applicant: Obalon Therapeutics, Inc.

Inventor： Mark C. Brister ,  Kaushik A. Patel ,  Andrew P. Rasdal ,  Nelson Quintana ,  Neil R. Drake ,  Antonio C. Llevares ,  Dubravka Markovic ,  Amy D. L. VandenBerg

IPC: A61F5/00 ,  A61B90/00 ,  A61L31/08 ,  A61L31/10 ,  A61M25/10 ,  A61M31/00 ,  A61B17/12

CPC classification number: A61F5/003 ,  A61B90/39 ,  A61F5/0036 ,  A61F5/0073 ,  A61F5/0083 ,  A61L31/088 ,  A61L31/10 ,  A61M25/10185 ,  A61M25/1029 ,  A61M31/002 ,  A61B17/1204 ,  A61B17/12099 ,  A61B2090/3966 ,  A61L2400/16 ,  A61L2420/02 ,  A61L2420/08 ,  A61M25/1027 ,  A61M2025/1031 ,  A61M2025/105 ,  Y10T156/1051

Abstract: Intragastric volume-occupying devices and methods for treating obesity are provided. The devices, which are inflated by carbon dioxide, include an aluminum or silicon oxide barrier layer providing carbon dioxide retention and an alkylene vinyl alcohol polymer layer providing structural integrity in vivo.

公开(公告)号：US20240307593A1

公开(公告)日：2024-09-19

申请号：US18634452

申请日：2024-04-12

Applicant: Ension, Inc.

Inventor： Patrick Cahalan ,  Linda Cahalan

IPC: A61L29/04 ,  A61L29/14 ,  C08L5/10 ,  C08L27/18 ,  C08L63/00 ,  C08L79/02

CPC classification number: A61L29/049 ,  A61L29/145 ,  C08L5/10 ,  C08L27/18 ,  C08L63/00 ,  C08L79/02 ,  A61L2420/02 ,  A61L2420/06

Abstract: A manufacturing method fora pipeline flow diverter or stent includes activating a blood-contacting metal surface of the medical device via i) propene plasma treatment or ii) contacting the surface with an organic solution comprising a silane functional compound having an ethylenically unsaturated functional group, wherein the organic solution follows a blood flow path through the medical device; grafting a polymeric hydrogel to the activated surface; bonding a positively charged spacer molecule to the polymeric hydrogel by contacting the polymeric hydrogel with a first wet chemistry treatment composition comprising an aqueous solution containing a cationic polymer, wherein the first wet chemistry treatment follows a blood flow path through the medical device; and covalently bonding heparin to the spacer molecule by contacting the spacer molecule with a second wet chemistry treatment composition comprising heparin, wherein the second wet chemistry treatment follows a blood flow path through the medical device.

公开(公告)号：US20240299630A1

公开(公告)日：2024-09-12

申请号：US18120330

申请日：2023-03-10

Applicant: Bard Access Systems, Inc.

Inventor： Ejaz Sajedul Haque ,  Nicholas P. Papadopoulos ,  Brendan Laine ,  James L. Freasier

IPC: A61L29/08 ,  A61L29/16

CPC classification number: A61L29/085 ,  A61L29/16 ,  A61L2300/404 ,  A61L2300/442 ,  A61L2300/608 ,  A61L2420/02

Abstract: Coated medical devices include coated catheters. For example, a coated catheter can include a catheter tube of a tubular substrate and a coating thereover. The tubular substrate can be of a first polymeric material transparent to electromagnetic radiation in a range of visible light. The coating can be of a second polymeric material anchored to the tubular substrate by chain ends of the second polymeric material impregnated in the first polymeric material by way of a spent visible-light photoinitiator. Methods of coating can include methods of coating medical devices such as the coated catheter. For example, a method of coating can include irradiating a tubular substrate impregnated with a visible-light photoinitiator with the foregoing electromagnetic radiation while the tubular substrate is disposed in an aqueous solution of a monomer, thereby initiating a radical polymerization of the monomer and coating the tubular substrate with the coating of the second polymer material.

公开(公告)号：US12064524B2

公开(公告)日：2024-08-20

申请号：US17574697

申请日：2022-01-13

Applicant: Soane Materials LLC

Inventor： David S. Soane ,  Juan Sebastian Colmenares ,  Allison Greene ,  Alexander Soane

IPC: A61L15/22 ,  A61F13/15 ,  A61L15/42 ,  A61L15/44 ,  A61L15/46 ,  A61L15/60

CPC classification number: A61L15/225 ,  A61F13/15642 ,  A61L15/425 ,  A61L15/44 ,  A61L15/46 ,  A61L15/60 ,  A61L2420/02

Abstract: The invention encompasses composite materials having a fibrous core that is at least partially covered by a water-swellable coating layer in which the water-swellable coating layer includes a water-swellable polymer. The invention also encompasses methods for manufacturing such a composite material, and further encompasses articles of manufacture made from such composite materials and methods for manufacturing such articles.