公开(公告)号：US20180134808A1

公开(公告)日：2018-05-17

申请号：US15865479

申请日：2018-01-09

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Irit SAGI ,  Tamar DANON ,  Netta SELA ,  Abraham SHANZER ,  Rina ARAD-YELLIN ,  Raghavendra KIKKERI

IPC: C07K16/44 ,  C07F3/06 ,  C07D233/61 ,  C07K16/40

CPC classification number: C07K16/44 ,  C07D233/61 ,  C07F3/06 ,  C07K16/40 ,  C07K2317/565 ,  C07K2317/76

Abstract: An antibody comprising an antigen recognition region which comprises CDR amino acid sequences set forth in SEQ ID NO: 7, 8, 9, 10, 11 and 12.

公开(公告)号：US20160002269A1

公开(公告)日：2016-01-07

申请号：US14766996

申请日：2014-02-13

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Abraham SHANZER ,  Galina MELMAN ,  Yaniv BARDA ,  Raghavendra KIKKERI ,  Boris KRAIZ ,  Larissa GINAT

IPC: C07F5/00 ,  C09D11/38 ,  G01N21/64 ,  C09K11/06 ,  A61K49/10

CPC classification number: C07F5/003 ,  A61K49/106 ,  C09D11/38 ,  C09K11/06 ,  C09K2211/182 ,  G01N21/6428 ,  G01N21/6486 ,  G01N2021/6432

Abstract: The present invention is directed to multinuclear lanthanides chiral clusters, based on phenyl-oxazoline-amide (POxA) ligands, and to methods of use thereof. The chiral clusters of this invention are highly fluorescent with high stability.

Abstract translation: 本发明涉及基于苯基 - 恶唑啉 - 酰胺（POxA）配体的多核镧系元素手性簇及其使用方法。 本发明的手性簇是具有高稳定性的高度荧光。

公开(公告)号：US20160257765A1

公开(公告)日：2016-09-08

申请号：US15161375

申请日：2016-05-23

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Irit SAGI ,  Tamar DANON ,  Netta SELA ,  Abraham SHANZER ,  Rina ARAD-YELLIN ,  Raghavendra KIKKERI

IPC: C07K16/44 ,  C07K16/40 ,  C07F3/06

CPC classification number: C07K16/44 ,  C07D233/61 ,  C07F3/06 ,  C07K16/40 ,  C07K2317/565 ,  C07K2317/76

Abstract: An antibody comprising an antigen recognition region which comprises CDR amino acid sequences set forth in SEQ ID NO: 7, 8, 9, 10, 11 and 12.