公开(公告)号：US20180134808A1

公开(公告)日：2018-05-17

申请号：US15865479

申请日：2018-01-09

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Irit SAGI ,  Tamar DANON ,  Netta SELA ,  Abraham SHANZER ,  Rina ARAD-YELLIN ,  Raghavendra KIKKERI

IPC: C07K16/44 ,  C07F3/06 ,  C07D233/61 ,  C07K16/40

CPC classification number: C07K16/44 ,  C07D233/61 ,  C07F3/06 ,  C07K16/40 ,  C07K2317/565 ,  C07K2317/76

Abstract: An antibody comprising an antigen recognition region which comprises CDR amino acid sequences set forth in SEQ ID NO: 7, 8, 9, 10, 11 and 12.

公开(公告)号：US20160002269A1

公开(公告)日：2016-01-07

申请号：US14766996

申请日：2014-02-13

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Abraham SHANZER ,  Galina MELMAN ,  Yaniv BARDA ,  Raghavendra KIKKERI ,  Boris KRAIZ ,  Larissa GINAT

IPC: C07F5/00 ,  C09D11/38 ,  G01N21/64 ,  C09K11/06 ,  A61K49/10

CPC classification number: C07F5/003 ,  A61K49/106 ,  C09D11/38 ,  C09K11/06 ,  C09K2211/182 ,  G01N21/6428 ,  G01N21/6486 ,  G01N2021/6432

Abstract: The present invention is directed to multinuclear lanthanides chiral clusters, based on phenyl-oxazoline-amide (POxA) ligands, and to methods of use thereof. The chiral clusters of this invention are highly fluorescent with high stability.

Abstract translation: 本发明涉及基于苯基 - 恶唑啉 - 酰胺（POxA）配体的多核镧系元素手性簇及其使用方法。 本发明的手性簇是具有高稳定性的高度荧光。

公开(公告)号：US20190127392A1

公开(公告)日：2019-05-02

申请号：US16168863

申请日：2018-10-24

Applicant: YEDA RESEARCH AND DEVELOPMENT CO. LTD.

Inventor： Barak DAYAN ,  Abraham SHANZER ,  Ori Ezrah MOR MARKOVSKY

IPC: C07F5/00 ,  G06N99/00

Abstract: A quantum device for interfacing Lanthanide ions with optical fields or microwave fields or both. The device includes waveguides or resonators or both for optical fields or microwave fields or for both. The device includes at least one surface to which a single customized Lanthanide molecular complex, or an ensemble, layer, multilayer or crystal of such, are attached or bonded. This places the Lanthanide ions within the optical or microwave fields or both. The ability to customize the molecular structure around each Lanthanide ion, and to control their orientation and position and nano-environment in general, enables minimizing the host lattice effects and non-radiative loss channels for each ion, and increasing their homogeneity. Accordingly, the advantages of the present invention include reduced inhomogeneities, narrower linewidths, extended fluorescence and coherence times, and higher operation temperatures. Devices which benefit from the present invention include lasers, amplifiers, sensors, quantum memories, repeaters and quantum information processing devices at optical fields, microwave fields, or both, including bi-directional optical-microwave convertors.

公开(公告)号：US20160257765A1

公开(公告)日：2016-09-08

申请号：US15161375

申请日：2016-05-23

Applicant: Yeda Research and Development Co. Ltd.

Inventor： Irit SAGI ,  Tamar DANON ,  Netta SELA ,  Abraham SHANZER ,  Rina ARAD-YELLIN ,  Raghavendra KIKKERI

IPC: C07K16/44 ,  C07K16/40 ,  C07F3/06

CPC classification number: C07K16/44 ,  C07D233/61 ,  C07F3/06 ,  C07K16/40 ,  C07K2317/565 ,  C07K2317/76

Abstract: An antibody comprising an antigen recognition region which comprises CDR amino acid sequences set forth in SEQ ID NO: 7, 8, 9, 10, 11 and 12.