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公开(公告)号：US4716120A
公开(公告)日：1987-12-29
申请号：US801649
申请日：1985-11-25
CPC分类号： A61K39/35 , Y10S436/809
摘要： A storage-stable, high potency allergenic extract is prepared by ultrafiltration, retaining fractions having molecular weights of from 1000 to 100,000, and treating the solution with gel polymer and/or carbon absorbents. The extract is dried to a moisture content of less than one weight percent water. The purified solution and aqueous reconstituted solutions of the dried extract provide a transparent, colorless solution which has greatly increased stability, remaining transparent and colorless for extended periods.
摘要翻译： 通过超滤制备储存稳定的高效力过敏原提取物，保留分子量为1000至100,000的级分，并用凝胶聚合物和/或碳吸收剂处理溶液。 将提取物干燥至含水量小于1重量％的水分。 干燥提取物的纯化溶液和水性重构溶液提供透明的无色溶液，其具有大大增加的稳定性，长时间保持透明和无色。
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公开(公告)号：US4963356A
公开(公告)日：1990-10-16
申请号：US40216
申请日：1987-04-20
IPC分类号： A61K39/35
CPC分类号： A61K39/35
摘要： A storage-stable, high potency allergenic extract is prepared by ultrafiltration, retaining fractions having molecular weights of from 1000 to 100,000, and drying the retained fraction to a moisture content of less than one weight percent. The extract can also be pretreated with amylase before ultrafiltration, treated with affinity chromatography before drying, and/or treated with gamma radiation after drying.
摘要翻译： 通过超滤制备储存稳定的高效力过敏原提取物，保留分子量为1000至100,000的级分，并将残留的级分干燥至小于1重量％的含水量。 提取物也可以在超滤之前用淀粉酶进行预处理，在干燥之前用亲和层析处理，和/或干燥后用γ辐射处理。
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