公开(公告)号：US08690826B2

公开(公告)日：2014-04-08

申请号：US13666233

申请日：2012-11-01

Applicant: Zoll Circulation, Inc.

Inventor： Wayne A. Noda ,  Stelica Stelea

IPC: A61F7/12

CPC classification number: F04C2/18 ,  A61F7/0085 ,  A61F7/12 ,  A61F2007/0054 ,  A61F2007/0093 ,  A61F2007/0096 ,  A61F2007/126 ,  F04C15/0069 ,  F04C29/0064 ,  F04D13/024 ,  F04D29/606 ,  F25B2400/01 ,  F25B2600/0253 ,  F25B2700/1351 ,  F25D17/02

Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.

Abstract translation: 用于留置热交换导管的冷却系统包括热交换浴，其被配置为接收将导管和/或从该导管携带的导管。 加热/冷却液在浴中，与盐水交换热量。 加热/冷却流体流过包括制冷剂的热交换器和用于从制冷剂中除去热量的两个变速直流压缩机。 齿轮泵将工作流体循环到导管和从导管流出并且可移除地与泵支撑平台接合。

公开(公告)号：US20130158480A1

公开(公告)日：2013-06-20

申请号：US13771447

申请日：2013-02-20

Applicant: Zoll Circulation, Inc. ,  The Regents of the University of California

Inventor： Wayne A. Noda ,  Mike L. Jones ,  Scott M. Evans ,  Blair D. Walker ,  William J. Worthen ,  Yves Pierre Gobin

IPC: A61F7/12 ,  A61M5/44

CPC classification number: A61F7/12 ,  A61B2018/00011 ,  A61F7/123 ,  A61F2007/0054 ,  A61F2007/126 ,  A61M1/369 ,  A61M5/44 ,  A61M25/0009 ,  A61M25/1011

Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.

Abstract translation: 导管适于与诸如血管的体导管中流动的体液（例如血液）进行热交换。 导管包括设置在其远端处具有热交换区域的轴。 该区域可以包括中空纤维，其适于接收远离冷却的热交换流体，优选地在与体液相反的方向上流动。 中空纤维增强了接触的表面积，以及两种热交换流体和体液的混合。 导管可以定位成在身体的选择性区域产生低体温，或者定位成系统地冷却整个身体系统。

公开(公告)号：US20130296985A1

公开(公告)日：2013-11-07

申请号：US13934798

申请日：2013-07-03

Applicant: The Regents of the University of California ,  Zoll Circulation, Inc.

Inventor： Wayne A. Noda ,  Mike L. Jones ,  Scott M. Evans ,  Blair D. Walker ,  William J. Worthen ,  Yves Pierre Gobin

IPC: A61F7/12

CPC classification number: A61F7/12 ,  A61B2018/00011 ,  A61F7/123 ,  A61F2007/0054 ,  A61F2007/126 ,  A61M1/369 ,  A61M5/44 ,  A61M25/0009 ,  A61M25/1011

Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.

公开(公告)号：US20130060311A1

公开(公告)日：2013-03-07

申请号：US13666233

申请日：2012-11-01

Applicant: Zoll Circulation, Inc.

Inventor： Wayne A. Noda ,  Stelica Stelea

IPC: A61F7/12

CPC classification number: F04C2/18 ,  A61F7/0085 ,  A61F7/12 ,  A61F2007/0054 ,  A61F2007/0093 ,  A61F2007/0096 ,  A61F2007/126 ,  F04C15/0069 ,  F04C29/0064 ,  F04D13/024 ,  F04D29/606 ,  F25B2400/01 ,  F25B2600/0253 ,  F25B2700/1351 ,  F25D17/02

Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.

公开(公告)号：US20130046365A1

公开(公告)日：2013-02-21

申请号：US13659123

申请日：2012-10-24

Applicant: Zoll Circulation, Inc.

Inventor： Wayne A. Noda ,  Stelica Stelea

IPC: A61F7/12

CPC classification number: F04C2/18 ,  A61F7/0085 ,  A61F7/12 ,  A61F2007/0054 ,  A61F2007/0093 ,  A61F2007/0096 ,  A61F2007/126 ,  F04C15/0069 ,  F04C29/0064 ,  F04D13/024 ,  F04D29/606 ,  F25B2400/01 ,  F25B2600/0253 ,  F25B2700/1351 ,  F25D17/02

Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.

Abstract translation: 用于留置热交换导管的冷却系统包括热交换浴，其被配置为接收将导管和/或从该导管携带的导管。 加热/冷却液在浴中，与盐水交换热量。 加热/冷却流体流过包括制冷剂的热交换器和用于从制冷剂中除去热量的两个变速直流压缩机。 齿轮泵将工作流体循环到导管和从导管流出并且可移除地与泵支撑平台接合。

公开(公告)号：US20170284390A1

公开(公告)日：2017-10-05

申请号：US15490643

申请日：2017-04-18

Applicant: Zoll Circulation, Inc.

Inventor： Wayne A. Noda ,  Stelica Stelea

IPC: F04C2/18 ,  F04C15/00

Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.

公开(公告)号：US09624926B2

公开(公告)日：2017-04-18

申请号：US13659123

申请日：2012-10-24

Applicant: Zoll Circulation, Inc.

Inventor： Wayne A. Noda ,  Stelica Stelea

IPC: F04C2/18 ,  F04C15/00 ,  F04C29/00 ,  F04D13/02 ,  F04D29/60 ,  A61F7/00 ,  A61F7/12 ,  F25D17/02

CPC classification number: F04C2/18 ,  A61F7/0085 ,  A61F7/12 ,  A61F2007/0054 ,  A61F2007/0093 ,  A61F2007/0096 ,  A61F2007/126 ,  F04C15/0069 ,  F04C29/0064 ,  F04D13/024 ,  F04D29/606 ,  F25B2400/01 ,  F25B2600/0253 ,  F25B2700/1351 ,  F25D17/02

Abstract: A cooling system for an indwelling heat exchange catheter includes a heat exchange bath that is configured to receive a conduit that carries saline to and from the catheter. A heating/cooling fluid is in the bath and exchanges heat with the saline. The heating/cooling fluid flows through a heat exchanger that includes a refrigerant and two variable speed DC compressor for removing heat from the refrigerant. A gear pump circulates the working fluid to and from the catheter and is removably engaged with a pump support platform.

公开(公告)号：US08888729B2

公开(公告)日：2014-11-18

申请号：US13934798

申请日：2013-07-03

Applicant: Zoll Circulation, Inc. ,  The Regents of the University of California

Inventor： Wayne A. Noda ,  Mike L. Jones ,  Scott M. Evans ,  Blair D. Walker ,  William J. Worthen ,  Yves Pierre Gobin

IPC: A61M37/00 ,  A61F7/00 ,  A61F7/12 ,  A61M5/44 ,  A61B18/00 ,  A61M1/36 ,  A61M25/00 ,  A61M25/10

CPC classification number: A61F7/12 ,  A61B2018/00011 ,  A61F7/123 ,  A61F2007/0054 ,  A61F2007/126 ,  A61M1/369 ,  A61M5/44 ,  A61M25/0009 ,  A61M25/1011

Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.

Abstract translation: 导管适于与诸如血管的体导管中流动的体液（例如血液）进行热交换。 导管包括设置在其远端处具有热交换区域的轴。 该区域可以包括中空纤维，其适于接收远离冷却的热交换流体，优选地在与体液相反的方向上流动。 中空纤维增强了接触的表面积，以及两种热交换流体和体液的混合。 导管可以定位成在身体的选择性区域产生低体温，或者定位成系统地冷却整个身体系统。

公开(公告)号：US08753302B2

公开(公告)日：2014-06-17

申请号：US13771447

申请日：2013-02-20

Applicant: Zoll Circulation, Inc. ,  The Regents of the University of California

Inventor： Wayne A. Noda ,  Mike L. Jones ,  Scott M. Evans ,  Blair D. Walker ,  William J. Worthen ,  Yves Pierre Gobin

IPC: A61M37/00

CPC classification number: A61F7/12 ,  A61B2018/00011 ,  A61F7/123 ,  A61F2007/0054 ,  A61F2007/126 ,  A61M1/369 ,  A61M5/44 ,  A61M25/0009 ,  A61M25/1011

Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.