公开(公告)号：US5693081A

公开(公告)日：1997-12-02

申请号：US540864

申请日：1995-10-11

申请人： Eric S. Fain ,  Drew A. Hoffman ,  Benjamin D. Pless

发明人： Eric S. Fain ,  Drew A. Hoffman ,  Benjamin D. Pless

IPC分类号： A61N1/04 ,  A61N1/05

CPC分类号： A61N1/0573 ,  A61N1/0563

摘要： A lead system for use with an implantable cardioverter/defibrillator is disclosed. The lead system includes a fixation hook positioned approximately half-way between the distal tip of the lead and the tricuspid valve. The distal tip of the lead is positioned at the apex of the right ventricle and may or may not be secured there by a second fixation means such as a screw tip or tines. The fixation hook allows the defibrillation electrode to be accurately positioned by the patient's surgeon and maintained in contact with the septum wall of the patient's heart. By providing such intimate contact between the defibrillation electrode and the septum wall, defibrillation thresholds are reduced.

摘要翻译： 公开了一种与植入式心律转复除颤器一起使用的引导系统。 引导系统包括定位在引线的远端和三尖瓣之间大致中途的固定钩。 引线的远端位于右心室的顶点处，并且可以通过第二固定装置（例如螺钉尖端或尖齿）固定或不固定。 固定钩允许除颤电极被患者的外科医生精确地定位并保持与患者心脏的隔膜壁接触。 通过在除颤电极和隔膜壁之间提供这种紧密接触，降低了除颤阈值。

公开(公告)号：US5425748A

公开(公告)日：1995-06-20

申请号：US102437

申请日：1993-08-05

申请人： Benjamin D. Pless

发明人： Benjamin D. Pless

IPC分类号： A61N1/39 ,  A61N1/36

CPC分类号： A61N1/3956

摘要： An implantable defibrillator and method for its use are disclosed. Amplified heart signals are fed back to a fibrillating heart to cause defibrillation by creating consistent enhancement and/or interference between the natural electrical signals in the heart and the coherent defibrillation signal. A unipolar endocardial sensing lead positioned in the right ventricular apex provides sensed electrical signals from the heart to a differential amplifier located in an implantable defibrillator. The amplified signal is provided to a sample and hold circuit which is disconnected from the amplifier by a switch during delivery of a defibrillation signal. The amplified heart signal from the sample and hold circuit is conditioned in a linear or non-linear manner and then further amplified by an isolation amplifier. The signal from the isolation amplifier is applied to the heart for periods of on the order of hundreds to thousands of milliseconds. A detector senses the amplitude of the signal at a point between the differential amplifier and the isolation amplifier and discontinues the defibrillation pulses upon detection of reduced cardiac activity for a predetermined period of time.

摘要翻译： 公开了一种植入式除颤器及其使用方法。 放大的心脏信号通过在心脏中的自然电信号和相干除颤信号之间产生一致的增强和/或干扰而被反馈到原纤维心脏引起除颤。 定位在右心室顶点的单极心内膜感测引线提供从心脏到位于可植入除颤器中的差分放大器的感测电信号。 放大的信号被提供给采样和保持电路，其在除颤信号的传送期间由开关与放大器断开连接。 来自采样和保持电路的放大心脏信号以线性或非线性方式调节，然后由隔离放大器进一步放大。 来自隔离放大器的信号被施加到心脏数百到数千毫秒级的时间段。 检测器感测差分放大器和隔离放大器之间的信号的幅度，并且在预定时间段内检测到心脏活动降低时，中断除颤脉冲。

公开(公告)号：US5411544A

公开(公告)日：1995-05-02

申请号：US145839

申请日：1993-11-02

申请人： Craig E. Mar ,  M. Elizabeth Bush ,  Benjamin D. Pless

发明人： Craig E. Mar ,  M. Elizabeth Bush ,  Benjamin D. Pless

IPC分类号： A61N1/04 ,  A61N1/05

CPC分类号： A61N1/0563

摘要： An implantable cardiac defibrillation lead is provided in which surface modification and deposition techniques are utilized to provide improved electrical and mechanical characteristics. The surface of an electrode can thereby be matched to the heart tissue for biocompatibility while at the same time providing for the appropriate electrical and mechanical characteristics of the electrode material.

摘要翻译： 提供了可植入的心脏除颤引线，其中使用表面改性和沉积技术来提供改善的电气和机械特性。 因此，电极的表面可以与心脏组织匹配以用于生物相容性，同时提供电极材料的适当的电气和机械特性。

公开(公告)号：US5027814A

公开(公告)日：1991-07-02

申请号：US354625

申请日：1989-05-19

申请人： Kenneth J. Carroll ,  Benjamin D. Pless

发明人： Kenneth J. Carroll ,  Benjamin D. Pless

IPC分类号： A61N1/37 ,  A61N1/39

CPC分类号： A61N1/3956 ,  A61N1/3702

摘要： An implantable medical device includes electrodes coupled to a patient's heart and sensing circuitry having inputs connected to the electrodes for sensing analog cardiac electrical signals from one of the atrial or ventricular channels. The sensing circuitry includes waveform digitization network means for converting the analog atrial or ventricular electrical signals into a parallel output format sign/magnitude digitized output signal.

摘要翻译： 可植入医疗装置包括耦合到患者心脏的电极和感测电路，感测电路具有连接到电极的输入，用于感测来自心房或心室通道之一的模拟心电信号。 感测电路包括用于将模拟心房或心室电信号转换为并行输出格式符号/幅度数字化输出信号的波形数字化网络装置。

公开(公告)号：US4972835A

公开(公告)日：1990-11-27

申请号：US353955

申请日：1989-05-19

申请人： Kenneth J. Carroll ,  Benjamin D. Pless

发明人： Kenneth J. Carroll ,  Benjamin D. Pless

IPC分类号： A61N1/365 ,  A61N1/39

CPC分类号： A61N1/365 ,  A61N1/3931

摘要： An implantable cardiac defibrillator includes electrodes coupled to a patient's heart, a sensing system having inputs connected to the electrodes for sensing cardiac electrical signals from the atrial and/or ventricular channels, means for storing a charge, and means for delivering a shock to the heart. The sensing system includes switched capacitor means for amplifying the cardiac electrical signal with non-binary gain changing steps.

摘要翻译： 可植入心脏除颤器包括耦合到患者心脏的电极，具有连接到电极的输入的感测系统，用于感测来自心房和/或心室通道的心脏电信号，用于存储电荷的装置，以及用于向心脏递送震动的装置 。 感测系统包括用于以非二进制增益改变步骤放大心脏电信号的开关电容器装置。

公开(公告)号：US4967747A

公开(公告)日：1990-11-06

申请号：US353952

申请日：1989-05-19

申请人： Kenneth J. Carroll ,  Benjamin D. Pless

发明人： Kenneth J. Carroll ,  Benjamin D. Pless

IPC分类号： A61N1/362 ,  A61N1/39

CPC分类号： A61N1/3622 ,  A61N1/3931

摘要： An implantable cardiac defibrillator includes electrodes coupled to a patient's heart, sensing circuitry having inputs connected to the electrodes for sensing cardiac electrical signals, charging means for storing a charge, and discharge means for delivering a shock to the heart. The sensing circuitry includes switched capacitor gain/filter means for providing an output signal which is transient-free during a gain change operation and which maintains a constant filter bandwidth for each gain setting.

摘要翻译： 可植入心脏除颤器包括耦合到患者心脏的电极，具有连接到用于感测心脏电信号的电极的输入的感测电路的感测电路，用于存储电荷的充电装置和用于向心脏递送震动的放电装置。 感测电路包括开关电容器增益/滤波器装置，用于在增益改变操作期间提供无瞬变的输出信号，并且为每个增益设置保持恒定的滤波器带宽。

公开(公告)号：US4964406A

公开(公告)日：1990-10-23

申请号：US354467

申请日：1989-05-19

申请人： Kenneth J. Carroll ,  Benjamin D. Pless

发明人： Kenneth J. Carroll ,  Benjamin D. Pless

IPC分类号： A61N1/362 ,  A61N1/39

CPC分类号： A61N1/3622 ,  A61N1/3931

摘要： An implantable cardiac defibrillator employing a switched capacitor stage wherein the switches are clocked in a non-50%/50% ratio such that an operational amplifier has greater than 50% of the clock period to acquire the desired voltage and less than 50% of the clock period to hold the acquired voltage, thereby allowing the circuit to run at an overall lower current drain.

摘要翻译： 一种可植入心脏除颤器，其采用开关电容器级，其中开关以非50％/ 50％的比率被计时，使得运算放大器具有大于时钟周期的50％以获得期望电压并小于50％ 时钟周期以保持获取的电压，从而允许电路在整体较低的电流消耗下运行。

公开(公告)号：US4599523A

公开(公告)日：1986-07-08

申请号：US580898

申请日：1984-02-16

申请人： Benjamin D. Pless ,  Lawrence J. Stotts

发明人： Benjamin D. Pless ,  Lawrence J. Stotts

IPC分类号： A61N1/362 ,  H02J7/00 ,  H02J1/14 ,  A61N1/378

CPC分类号： A61N1/362 ,  H02J7/0068 ,  Y10T307/406 ,  Y10T307/461 ,  Y10T307/484

摘要： A priority switching circuit for providing a minimum voltage to a voltage sensitive load while charging a second load drawing a high current includes a battery, comparator, capacitor, and a voltage regulator. The output of the comparator causes the battery to be connected to the capacitor whenever the voltage across the capacitor drops below a predetermined minimum and causes the battery to be connected to the high current load when the voltage across the capacitor rises to a predetermined maximum. The circuit provides a varied switching frequency as the internal impedance of the battery increases with age. The voltage regulator provides a constant reference voltage which is used by the comparator to provide the switching control signals.

摘要翻译： 用于在对施加大电流的第二负载充电的同时向电压敏感负载提供最小电压的优先切换电路包括电池，比较器，电容器和电压调节器。 当电容器两端的电压下降到预定的最小值以下时，比较器的输出使得电池连接到电容器，并且当电容器两端的电压上升到预定的最大值时，使电池连接到高电流负载。 该电路随着电池的内部阻抗随着年龄的增长而提供不同的开关频率。 电压调节器提供恒定的参考电压，由比较器用来提供开关控制信号。