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    PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR NON-ALCOHOLIC STEATOHEPATITIS
    111.
    发明申请
    PROPHYLACTIC AND/OR THERAPEUTIC AGENT FOR NON-ALCOHOLIC STEATOHEPATITIS 审中-公开
    非酒精性止痛药的预防和/或治疗药物

    公开(公告)号：US20140221390A1

    公开(公告)日：2014-08-07

    申请号：US14162181

    申请日：2014-01-23

    Applicant: Kowa Company, Ltd.

    Inventor： Haruki Shibata ,  Yasunobu Yoshinaka ,  Kimiyuki Shibuya

    IPC: C07D401/12

    CPC classification number: C07D401/12 ,  A61K31/496

    Abstract: Provided is a compound useful in the prevention and treatment of non-alcoholic steatohepatitis. A prophylactic and/or therapeutic agent for non-alcoholic steatohepatitis which contains, as the active ingredient, 2-[4-[2-(benzimidazol-2-ylthio)ethyl]piperazin-1-yl]-N-[2,4-bis(methylthio)-6-methyl-3-pyridyl]acetamide, an acid-addition salt thereof, or a solvate of the same.

    Abstract translation: 提供了用于预防和治疗非酒精性脂肪性肝炎的化合物。 含有作为活性成分的2- [4- [2-（苯并咪唑-2-基硫基）乙基]哌嗪-1-基] -N- [2,4（ⅰ））的非酒精性脂肪性肝炎的预防和/或治疗剂 - 双（甲硫基）-6-甲基-3-吡啶基]乙酰胺，其酸加成盐或其溶剂合物。

    Novel cyclic diamine compounds and medicine containing the same
    112.
    发明申请
    Novel cyclic diamine compounds and medicine containing the same 失效
    新型环状二胺化合物及其含有药物

    公开(公告)号：US20040038987A1

    公开(公告)日：2004-02-26

    申请号：US10371234

    申请日：2003-02-20

    Applicant: Kowa Company, Ltd.

    Inventor： Kimiyuki Shibuya ,  Katsumi Kawamine ,  Yukihiro Sato ,  Toru Miura ,  Chiyoka Ozaki ,  Toshiyuki Edano ,  Mitsuteru Hirata ,  Tadaaki Ohgiya

    IPC: A61K031/496 ,  C07D417/02 ,  C07D413/02 ,  C07D43/02

    CPC classification number: C07D263/58 ,  C07D235/28 ,  C07D277/74 ,  C07D401/12 ,  C07D413/12 ,  C07D417/12 ,  C07F9/650952 ,  C07F9/65583

    Abstract: The present invention offers novel cyclic diamine compounds and a pharmaceutical composition containing the same. The present invention relates to a compound represented by the formula (I) or salt(s) or solvate(s) thereof. 1 (In the formula, 2 is an optionally substituted divalent residue of benzene, pyridine, cyclohexane or naphthalene or is a vinylene group where Ar is an optionally substituted aryl group; X is nullNHnull, oxygen atom or sulfur atom; Y is nullNR1null, oxygen atom, sulfur atom, sulfoxide or sulfone; Z is a single bond or nullNR2null; R1 is hydrogen atom, optionally substituted lower alkyl group, optionally substituted aryl group or optionally substituted silyl lower alkyl group; R2 is hydrogen atom, optionally substituted lower alkyl group, optionally substituted aryl group or optionally substituted silyl lower alkyl group; l is an integer of from 0 to 15; m is an integer of 2 or 3; and n is an integer of from 0 to 3). The compound of the present invention is useful as a pharmaceutical composition, particuarly as an inhibitor of acyl coenzyme A cholesterol acyltransferase (ACAT).

    Abstract translation: 本发明提供新的环状二胺化合物和含有它们的药物组合物。 本发明涉及由式（I）表示的化合物或其盐或溶剂化物。 （式中，是苯，吡啶，环己烷或萘的任意取代的二价残基，或者是亚乙烯基，其中Ar是任意取代的芳基; X是-NH-，氧原子或硫原子; Y是-NR1- ，氧原子，硫原子，亚砜或砜; Z是单键或-NR2-; R 1是氢原子，任选取代的低级烷基，任选取代的芳基或任选取代的甲硅烷基低级烷基; R 2是氢原子， 取代的低级烷基，任选取代的芳基或任选取代的甲硅烷基低级烷基; l为0至15的整数; m为2或3的整数; n为0至3的整数）。 本发明的化合物可用作药物组合物，特别是作为酰基辅酶A胆固醇酰基转移酶（ACAT）的抑制剂。

    MEDICAL PROGRAM AND MEDICAL EXAMINATION SYSTEM
    113.
    发明申请
    MEDICAL PROGRAM AND MEDICAL EXAMINATION SYSTEM 有权

    公开(公告)号：US20250030814A1

    公开(公告)日：2025-01-23

    申请号：US18569580

    申请日：2022-06-16

    Applicant: Kowa Company, Ltd.

    Inventor： Takahiro SUZUKI ,  Atsushi KAKUUCHI

    IPC: H04N5/91 ,  A61B3/00 ,  A61B3/14 ,  G06T7/00 ,  G16H30/20 ,  G16H40/67

    Abstract: Provided is a non-statutory computer-readable medium storing thereon a medical program for implementing various kinds of processing in a terminal device used together with a medical examination device including an imaging camera, in order to play a video live and record the video, while maintaining usability of the medical examination device including the imaging camera, the video being generated by imaging by the medical examination device. The medical program, when executed, causes a processor of the terminal device to perform: playing video data live and displaying the video data on a display unit of the terminal device, the video data being captured and simultaneously transmitted in real time by the medical examination device; and controlling start/stop of recording of the video data that is currently played live based on a predetermined operation.

    MULTIPLEXER AND IMAGING SYSTEM
    118.
    发明公开
    MULTIPLEXER AND IMAGING SYSTEM 审中-公开

    公开(公告)号：US20230370186A1

    公开(公告)日：2023-11-16

    申请号：US18030567

    申请日：2021-10-07

    Applicant: KOWA COMPANY, LTD.

    Inventor： Tomohisa AZEGAMI ,  Tomoya FUKUDA

    IPC: H04J3/06 ,  H04N5/073

    CPC classification number: H04J3/0652 ,  H04N5/0736

    Abstract: Multiplexer (100) according to the present invention includes: an input unit (11) to which a plurality of image signals based on a first data communication standard are input, the image signals being acquired by respective imaging devices (2); an output unit (14) that outputs an image signal based on a second data communication standard having a data transfer rate lower than that of the first data communication standard; and a storage unit (12) that temporarily buffers the image signals input from the input unit (11). With such a multiplexer 100, it is possible to collectively convert the image data acquired by a plurality of imaging devices adopting a certain data communication standard into another data communication standard and suppress the data transfer delay caused by the conversion.

    Telescope
    119.
    外观设计
    Telescope 有权

    公开(公告)号：USD1003963S1

    公开(公告)日：2023-11-07

    申请号：US35513105

    申请日：2021-06-08

    Applicant: KOWA COMPANY, LTD.

    Designer： Naoki Kambe ,  Takayuki Fujioka ,  Yasunari Oguchi

    Abstract: 1. Telescope
    2. Telescope
    1.1 : Perspective view 1
    1.2 : Perspective view 2
    1.3 : Front
    1.4 : Back
    1.5 : Right
    1.6 : Top
    1.7 : Bottom
    1.8 : Left
    2.1 : Perspective view 1
    2.2 : Perspective view 2
    2.3 : Front
    2.4 : Back
    2.5 : Right
    2.6 : Top
    2.7 : Bottom
    2.8 : Left
    The broken lines shown in the drawings depict portions of the telescope that form no part of the claimed design.

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