公开(公告)号：US11230520B2

公开(公告)日：2022-01-25

申请号：US17142751

申请日：2021-01-06

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Robert H. Grubbs ,  Alexey Fedorov ,  Anton Toutov ,  Kerry N. Betz

IPC: C07C209/28 ,  C07C209/62 ,  C07C37/50 ,  C07C37/055 ,  C07C1/22 ,  C07C319/06 ,  C07F7/08

Abstract: The present disclosure describes methods for silylating aromatic organic substrates, and associated chemical systems, said methods comprising or consisting essentially of contacting the aromatic organic substrate with a mixture of (a) at least one organosilane and (b) at least one strong base, under conditions sufficient to silylate the aromatic substrate.

公开(公告)号：US20210323983A1

公开(公告)日：2021-10-21

申请号：US17332394

申请日：2021-05-27

Applicant: California Institute Of Technology

Inventor： Anton Toutov ,  Wenbo Liu ,  David P. Schuman ,  Brian M. Stoltz ,  Robert H. Grubbs

IPC: C07F7/08 ,  C07F7/18

Abstract: The present disclosure is directed to methods of silylating organic substrates containing C—H or O—H bonds. In some embodiments, the methods use compositions that are derived from the preconditioning of mixtures of hydrosilanes or organodisilanes with bases, including metal hydroxide, metal alkoxide, metal silanoates, potassium amides, and/or graphitic potassium bases.

公开(公告)号：US11104693B2

公开(公告)日：2021-08-31

申请号：US16384178

申请日：2019-04-15

Applicant: California Institute Of Technology

Inventor： Anton Toutov ,  Kerry Betz ,  Andrew M. Romine ,  Robert H. Grubbs

IPC: C07F7/21 ,  C07D235/08 ,  C07F7/18 ,  C07F7/08

Abstract: The present disclosure is directed to methods for dehydrogenatively coupled hydrosilanes and alcohols, the methods comprising contacting an organic substrate having at least one organic alcohol moiety with a mixture of at least one hydrosilane and sodium and/or potassium hydroxide, the contacting resulting in the formation of a dehydrogenatively coupled silyl ether. The disclosure further described associated compositions and methods of using the formed products.

公开(公告)号：US11069921B2

公开(公告)日：2021-07-20

申请号：US16897771

申请日：2020-06-10

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY ,  HONDA MOTOR CO., LTD.

Inventor： Simon C. Jones ,  Victoria K. Davis ,  Christopher M. Bates ,  Nebojsa Momcilovic ,  Brett M. Savoie ,  Michael A. Webb ,  Thomas F. Miller, III ,  Robert H. Grubbs ,  Christopher Brooks ,  Kaoru Omichi

IPC: H01M10/0568 ,  H01M10/0525 ,  H01M10/0569 ,  H01M10/054 ,  C07C209/68

Abstract: Electrolyte solutions including at least one anhydrous fluoride salt and at least one non-aqueous solvent are presented. The fluoride salt includes an organic cation having a charge center (e.g., N, P, S, or O) that does not possess a carbon in the β-position or does not possess a carbon in the β-position having a bound hydrogen. This salt structure facilitates its ability to be made anhydrous without decomposition. Example anhydrous fluoride salts include (2,2-dimethylpropyl)trimethylammonium fluoride and bis(2,2-dimethylpropyl)dimethylammonium fluoride. Combining these fluoride salts with at least one fluorine-containing non-aqueous solvent (e.g., bis(2,2,2-trifluoroethyl)ether; (BTFE)) promotes solubility of the salt within the non-aqueous solvents. The solvent may be a mixture of at least one non-aqueous, fluorine-containing solvent and at least one other non-aqueous, fluorine or non-fluorine containing solvent (e.g., BTFE and propionitrile or dimethoxyethane). The electrolyte solutions may be employed in electrochemical cells, such as batteries, fuel cells, electrolysis systems, and capacitors.

公开(公告)号：US10927065B2

公开(公告)日：2021-02-23

申请号：US15889295

申请日：2018-02-06

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Robert H. Grubbs ,  Alexey Fedorov ,  Anton Toutov ,  Kerry N. Betz

IPC: C07C209/28 ,  C07C209/62 ,  C07C1/22 ,  C07C37/055 ,  C07C319/06 ,  C07C37/50 ,  C07F7/08

Abstract: The present disclosure describes methods for silylating aromatic organic substrates, and associated chemical systems, said methods comprising or consisting essentially of contacting the aromatic organic substrate with a mixture of (a) at least one organosilane and (b) at least one strong base, under conditions sufficient to silylate the aromatic substrate.

公开(公告)号：US10857530B2

公开(公告)日：2020-12-08

申请号：US16060466

申请日：2016-12-09

Applicant: Umicore AG & Co. KG ,  California Institute of Technology

Inventor： Adam M. Johns ,  T. Patrick Montgomery ,  Tonia S. Ahmed ,  Robert H. Grubbs ,  Richard L. Pederson

IPC: B01J31/22 ,  C07C6/06 ,  C07C6/04

Abstract: This invention relates generally to metathesis catalysts and the use of such catalysts in the metathesis of olefins and olefin compounds, more particularly, in the use of such catalysts in Z and E selective olefin metathesis reactions. The invention has utility in the fields of organometallics and organic synthesis.

公开(公告)号：US20200377528A1

公开(公告)日：2020-12-03

申请号：US16997226

申请日：2020-08-19

Applicant: California Institute Of Technology

Inventor： Anton A. Toutov ,  Kerry N. Betz ,  Andrew M. Romine ,  Robert H. Grubbs

IPC: C07F7/10

Abstract: The present disclosure is directed at methods of forming an N—Si silyl bond, the method comprising contacting an organic substrate comprising an aromatic amine having at least one N—H bond with a mixture comprising of (a) at least one hydrosilane and (b) at least one hydroxide or alkoxide, under conditions sufficient to form the N—Si bond. The disclosure is further directed to the compositions involved in these methods and the products that result therefrom.

公开(公告)号：US10827950B2

公开(公告)日：2020-11-10

申请号：US15061984

申请日：2016-03-04

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY

Inventor： Hyuck Choo ,  Frank L. Brodie ,  Robert H. Grubbs

IPC: A61B5/11 ,  A61B5/00 ,  A61B5/107

Abstract: A position sensing apparatus includes a position sensor, a voltage/current detector, and an alarm. The position sensor is coupled to the body part and includes a capsule, and first and second electrodes. The capsule has an interior volume configured to contain a liquid with a first density, and a contact member having a second density different from the first density. The first and second electrodes are fixed to the capsule to define a sensor meridian that is coupled to a tilt angle of the body part, with each electrode having a distal portion in the interior volume of the capsule, and the distal portions being configured to form a circuit with the liquid or the contact member. The voltage/current detector is configured to detect a change in a state of the circuit, and the alarm is configured to respond to the voltage/current detector.

公开(公告)号：US10732321B2

公开(公告)日：2020-08-04

申请号：US15243788

申请日：2016-08-22

Applicant: California Institute of Technology

Inventor： Garret M. Miyake ,  Raymond Weitekamp ,  Robert H. Grubbs ,  Victoria Piunova

IPC: C08L87/00 ,  G02B1/00 ,  G02F1/00 ,  C08F222/40 ,  C08F293/00 ,  C08F299/00 ,  C08F222/04 ,  C08G81/00

Abstract: The invention provides a class of block copolymers having a plurality of chemically different blocks, at least a portion of which incorporating polymer side chain groups having a helical secondary structure. The invention also provides structures generated by self-assembly of polymer blends including at least one block copolymer component, such as a brush block polymer or wedge-type block polymer. The invention provides, for example, periodic nanostructures and microstructures generated by self-assembly of block copolymers and polymer blends comprising a mixture of at least one block copolymer component, such as a brush block copolymer, and at least a second component.

公开(公告)号：US10720666B2

公开(公告)日：2020-07-21

申请号：US15228876

申请日：2016-08-04

Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY ,  HONDA MOTOR CO., LTD.

Inventor： Simon C. Jones ,  Victoria K. Davis ,  Christopher M. Bates ,  Nebojsa Momcilovic ,  Brett M. Savoie ,  Michael A. Webb ,  Thomas F. Miller, III ,  Robert H. Grubbs ,  Christopher Brooks ,  Kaoru Omichi

IPC: H01M10/0568 ,  H01M10/0525 ,  H01M10/0569 ,  H01M10/054 ,  C07C209/68

Abstract: Electrolyte solutions including at least one anhydrous fluoride salt and at least one non-aqueous solvent are presented. The fluoride salt includes an organic cation having a charge center (e.g., N, P, S, or O) that does not possess a carbon in the β-position or does not possess a carbon in the β-position having a bound hydrogen. This salt structure facilitates its ability to be made anhydrous without decomposition. Example anhydrous fluoride salts include (2,2-dimethylpropyl)trimethylammonium fluoride and bis(2,2-dimethylpropyl)dimethylammonium fluoride. Combining these fluoride salts with at least one fluorine-containing non-aqueous solvent (e.g., bis(2,2,2-trifluoroethyl)ether; (BTFE)) promotes solubility of the salt within the non-aqueous solvents. The solvent may be a mixture of at least one non-aqueous, fluorine-containing solvent and at least one other non-aqueous, fluorine or non-fluorine containing solvent (e.g., BTFE and propionitrile or dimethoxyethane). The electrolyte solutions may be employed in electrochemical cells, such as batteries, fuel cells, electrolysis systems, and capacitors.