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131.
公开(公告)号:US20210220379A1
公开(公告)日:2021-07-22
申请号:US16642989
申请日:2018-08-30
Applicant: MOR RESEARCH APPLICATIONS LTD.
Inventor: Marina VOROBIOV , Amos DOUVDEVANI , Yosef HAVIV , Boris ROGCHEV
IPC: A61K31/7034 , A61M1/28
Abstract: Peritoneal dialysis fluid (PDF) comprising at least one inhibitor of glucose transport and compositions comprising same are provided. Use of a PDF and a glucose transport inhibitor such as a sodium-glucose co-transporter (SGLT) inhibitor decreases glucose absorption into the circulation of patients treated with peritoneal dialysis and, therefore, provides improved means for treating renal failure diseases.
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公开(公告)号:US11045489B2
公开(公告)日:2021-06-29
申请号:US16567233
申请日:2019-09-11
Applicant: MOR RESEARCH APPLICATIONS LTD.
Inventor: Smadar Avigad , Isaac Yaniv , Keren Shichrur
IPC: C12Q1/68 , A61K31/7105 , G01N33/574 , C12N15/113 , C12Q1/6886 , A61K31/4025 , A61K39/395
Abstract: Described herein are methods for determining the prognosis of a patient diagnosed with Acute Lymphoblastic Leukemia (ALL), and particularly determining the risk of disease relapse following standard treatment. Also described are systems of treatment that are directed by a health care provider, and which include the described prognostic methods and the treatments recommended for patients determined to have a specific relapse risk.
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公开(公告)号:US20210000492A1
公开(公告)日:2021-01-07
申请号:US16975953
申请日:2019-02-27
Applicant: MOR RESEARCH APPLICATIONS LTD.
Inventor: Nimrod ROZEN , Aharon AMIR
Abstract: A device for guiding a surgical instrument at a surgical site, comprising: at least one guide channel sized and fitted to slidingly accommodate a surgical instrument, said guide channel defining a guide longitudinal axis; and at least one guide support leg coupled to said guide and defining a support leg longitudinal axis, wherein an angle (a) of said guide longitudinal axis in respect to a surface of a surgical site is defined by at least one of (i) a length (L) of said support leg, and (ii) an angle (β) between said guide longitudinal axis and said support leg longitudinal axis.
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公开(公告)号:US20200222359A1
公开(公告)日:2020-07-16
申请号:US16491197
申请日:2018-03-05
Applicant: The State of Israel, Ministry of Agriculture & Rural Development, Agricultural Research Organization , Mor Research Applications Ltd.
Inventor: Hinanit KOLTAI , Yoram KAPULNIK , Moran MAZUZ , Timna NAFTALI
IPC: A61K31/352 , A61K36/185 , A61K31/05 , A61P1/00 , A61P29/00
Abstract: A method of treating an inflammatory disease in a subject in need thereof is provided. The method comprising administering to the subject a therapeutically effective amount of a liquid chromatography fraction of a cannabis extract comprising at least 75% tetrahydrocannabinolic acid (THCA), wherein the fraction comprises cannabis derived active ingredients other than the THCA.
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公开(公告)号:US20200093423A1
公开(公告)日:2020-03-26
申请号:US16316454
申请日:2017-07-11
Applicant: B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY , MOR RESEARCH APPLICATIONS LTD.
Inventor: Eliran DAFNA , Yaniv ZIGEL , Dvir BEN OR , Matan HALEVI , Ariel TARASIUK
Abstract: The present invention relates to a system and method for determining sleep quality parameters according to audio analyses, comprising: obtaining an audio recorded signal comprising sleep sounds of a subject; segmenting the signal into epochs; generating a feature vector for each epoch, wherein each of said feature vectors comprises one or more feature parameters that are associated with a particular characteristic of the signal and that are calculated according to the epoch signal or according to a signal generated from the epoch signal; inputting the generated feature vectors into a machine learning classifier and applying a preformed classifying model on the feature vectors that outputs a probabilities vector for each epoch, wherein each of the probabilities vectors comprises the probabilities of the epoch being each of the sleep quality parameters; inputting the probabilities vectors for each epoch into a machine learning time series model and applying a preformed sleep quality time series pattern function on said probabilities vectors that outputs an enhanced probabilities vector for each epoch; determining a final sleep quality parameter for each epoch by calculating the most probable sleep quality parameters sequence.
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136.
公开(公告)号:US20200022805A1
公开(公告)日:2020-01-23
申请号:US16483752
申请日:2018-03-01
Applicant: MOR RESEARCH APPLICATIONS LTD.
Inventor: Gonen OMER , Ori MAHLER
Abstract: Embodiments concern an intraocular implantable device operable comprising a disk-shaped body having a symmetry axis and which further comprises a light-transmissive portion and an opaque portion wherein the light-transmissive portion is decentered with respect to the symmetry axis.
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公开(公告)号:US20190388457A1
公开(公告)日:2019-12-26
申请号:US16567233
申请日:2019-09-11
Applicant: MOR RESEARCH APPLICATIONS LTD.
Inventor: Smadar AVIGAD , Isaac YANIV , Keren SHICHRUR
IPC: A61K31/7105 , G01N33/574 , C12Q1/6886 , A61K31/4025 , A61K39/395
Abstract: Described herein are methods for determining the prognosis of a patient diagnosed with Acute Lymphoblastic Leukemia (ALL), and particularly determining the risk of disease relapse following standard treatment. Also described are systems of treatment that are directed by a health care provider, and which include the described prognostic methods and the treatments recommended for patients determined to have a specific relapse risk.
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公开(公告)号:US20190167711A1
公开(公告)日:2019-06-06
申请号:US16272352
申请日:2019-02-11
Applicant: MOR RESEARCH APPLICATIONS LTD.
Inventor: Smadar AVIGAD , Isaac YANIV , Keren SHICHRUR
IPC: A61K31/7105 , C12Q1/6886 , A61P35/02
Abstract: Provided herein is the use of miR-451 as a biomarker in prognosis of anti-ALL treatment modalities, in early diagnosis of ALL relapse risk, and/or in identifying an ALL patient that can benefit from a treatment modality that affects one or more miR-451-related metabolic pathways.
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公开(公告)号:US10147185B2
公开(公告)日:2018-12-04
申请号:US15509925
申请日:2015-09-08
Applicant: B.G. NEGEV TECHNOLOGIES AND APPLICATIONS LTD., AT BEN-GURION UNIVERSITY , MOR RESEARCH APPLICATIONS LTD.
Inventor: Tamar Riklin Raviv , Ilan Shelef , Itzhak Hershkovich , Ohad Chitrit
Abstract: A method for three-dimensional interactive segmentation, including: receiving a three-dimensional medical image of an interior volume of a patient's body; automatically performing three dimensional segmentation on the three dimensional medical image to detect and define a region of interest, wherein the performing of the three dimensional segmentation comprises automatically determining a boundary defining the region of interest; receiving from a user spatial information indicating one or more regions of disagreement in the three-dimensional medical image with respect to the determined boundary; and updating the three dimensional segmentation of the three dimensional medical image based on the spatial information received from the user, wherein the updating comprises updating the determined boundary based on the spatial information to redefine the area of interest.
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公开(公告)号:US10058515B2
公开(公告)日:2018-08-28
申请号:US15877665
申请日:2018-01-23
Applicant: MOR RESEARCH APPLICATIONS LTD.
Inventor: Moshe Yeshurun
CPC classification number: A61K31/05 , A61K9/0014 , A61K9/0053 , A61K9/0095 , A61K45/06
Abstract: The invention provides methods for preventing, ameliorating and treating the acute and chronic forms of graft-versus-host disease (GVHD) by using Cannabidiol compositions.
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