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    Device with Chamber and First and Second Valves in Communication Therewith, and Related Method
    131.
    发明申请
    Device with Chamber and First and Second Valves in Communication Therewith, and Related Method 有权
    具有腔室和第一和第二阀的通信装置及相关方法

    公开(公告)号：US20080121668A1

    公开(公告)日：2008-05-29

    申请号：US11938103

    申请日：2007-11-09

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: B65D35/38

    CPC classification number: B65D47/205 ,  A45D40/26 ,  B65D35/06 ,  B65D35/08 ,  B65D35/38 ,  B65D83/0055

    Abstract: A container including a nozzle and body depending therefrom. The body is preferably tubular and defines an interior which retains a product to be dispensed. A cap engages the nozzle to prevent inadvertent release of the product. In order to dispense the product, the cap is removed and pressure is applied to the body and the nozzle allows release of the product. The nozzle releases the product without exposing the remaining product to the external atmosphere, thus the sterility of the interior of the body is maintained and the shelf life of the product is increased. The nozzle includes an inner body, coupled to the tubular body, surrounded by a flexible outer cover. A seam between the inner body and flexible outer cover forms a one-way release valve wherein a portion of the seam remains closed during dispensing the product.

    Abstract translation: 一种容器，其包括从其排出的喷嘴和主体。 主体优选地是管状的并且限定保持要分配的产品的内部。 盖子与喷嘴接合以防止产品的意外释放。 为了分配产品，盖被去除并且压力施加到主体上，并且喷嘴允许释放产品。 喷嘴释放产品而不将剩余的产品暴露于外部大气，从而维持身体内部的不整洁性并且提高了产品的保质期。 该喷嘴包括一个连接到管状主体的内部主体，被一个柔性的外盖包围。 内体和柔性外盖之间的接缝形成单向释放阀，其中在分配产品期间，接缝的一部分保持关闭。

    Needle penetrable and laser resealable lyophilization device and related method
    134.
    发明申请
    Needle penetrable and laser resealable lyophilization device and related method 有权

    公开(公告)号：US20080039773A1

    公开(公告)日：2008-02-14

    申请号：US11789498

    申请日：2007-04-24

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: A61M1/00

    CPC classification number: F26B5/06

    Abstract: A device and related method are provided for lyophilizing a substance within the device and storing therein the lyophilized substance. The device is penetrable by a needle for filling the device with the substance to be lyophilized, and a resulting needle hole in the device is laser resealable by transmitting thereon laser radiation from a laser source. The device defines a chamber for receiving therein the substance to be lyophilized. A needle penetrable and laser resealable portion of the device is pierceable with a needle to form a needle aperture therethrough to fill the chamber with the substance to be lyophilized through the needle, and is laser resealable to hermetically seal the needle aperture by applying laser radiation thereto. A filter is connectable in fluid communication between an interior and exterior of the chamber for permitting fluid to flow therethrough in a direction from the interior to the exterior of the chamber, and for substantially preventing contaminants from flowing therethrough in a direction from the exterior to the interior of the chamber.

    Dispenser with sealed chamber, one-way valve and needle penetrable and laser resealable stopper
    137.
    发明授权
    Dispenser with sealed chamber, one-way valve and needle penetrable and laser resealable stopper 有权
    分配器带密封腔，单向阀和针头可穿透，激光可重复密封塞子

    公开(公告)号：US07290573B2

    公开(公告)日：2007-11-06

    申请号：US11195520

    申请日：2005-08-01

    Applicant: Daniel Py ,  Norbert M. Assion ,  Julian V. Chan

    Inventor： Daniel Py ,  Norbert M. Assion ,  Julian V. Chan

    IPC: B65B1/04

    CPC classification number: B65D47/2031 ,  A45D40/26 ,  A61M5/31586 ,  A61M5/31595 ,  A61M5/50 ,  A61M5/502 ,  B65D35/06 ,  B65D35/08 ,  B65D35/38 ,  B65D35/44 ,  G01F11/027

    Abstract: A syringe is provided for the delivery of controlled, metered amounts of any of numerous different substances to humans or animals, such as medicaments, pharmaceuticals, cosmetics, and food products, or to deliver materials which may react upon exposure to air, such as glue. The syringes include a body and a plunger. Means are provided in the syringe body and the plunger to effect controlled movement of the plunger into the syringe to permit delivery of a pre-determined amount of the substance contained in the syringe. A one-way valve is provided at the dispensing tip of the syringe to hermetically seal the portion of the syringe containing the substance to be dispensed.

    Abstract translation: 提供注射器用于向人或动物（例如药物，药物，化妆品和食品）递送受控量的计量量的任何不同物质，或者输送在暴露于空气中可能反应的材料，例如胶 。 注射器包括身体和柱塞。 装置设置在注射器主体和柱塞中以实现柱塞到注射器中的受控运动，以允许输送预定量的包含在注射器中的物质。 在注射器的分配尖端处设置单向阀以气密地密封包含待分配物质的注射器的部分。

    Apparatus and method for needle filling and laser resealing
    139.
    发明授权
    Apparatus and method for needle filling and laser resealing 有权
    针刺和激光重新密封的装置和方法

    公开(公告)号：US07270158B2

    公开(公告)日：2007-09-18

    申请号：US11510961

    申请日：2006-08-28

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: B65B1/04

    CPC classification number: B65B7/161 ,  B65B3/003 ,  B65B7/00 ,  B65B37/06 ,  B65B43/54 ,  B65B51/22 ,  B65B55/04 ,  B65B55/08 ,  B65B57/00 ,  B65B65/02

    Abstract: An apparatus is provided for needle filling and thermally resealing containers having stoppers that are needle penetrable for filling the containers with a substance, and are thermally resealable for thermally sealing a needle hole in the stopper upon withdrawal of a needle therefrom. A container support of the apparatus supports at least one container having a resealable stopper in a substantially fixed position during needle filling and thermally resealing a needle hole in the stopper upon withdrawal of a needle therefrom. A manifold is drivingly mounted over the container support and comprises (1) a needle cartridge including a needle for penetrating the resealable stopper and introducing a substance through the needle and into the container, a needle mount for mounting the needle cartridge on the manifold, and a needle cover releasably coupled to the needle mount for covering the needle during transportation, installation and/or removal of the needle cartridge from the manifold, and that is removable from the needle cartridge upon mounting the needle cartridge to the manifold. The manifold further includes a thermal source for heating a needle penetrated region of the stopper and, in turn, sealing a needle hole in the stopper.

    Abstract translation: 提供了一种用于针头填充和热重新密封容器的装置，其具有用于针对物品填充容器的可穿刺的塞子，并且在从其中取出针时，可热再密封用于热封塞塞中的针孔。 装置的容器支撑件支撑至少一个具有可重新封闭的塞子的容器，该容器在针填充期间处于基本上固定的位置，并且在从针头中​​取出针时，在塞子中对针孔进行热再密封。 歧管被驱动地安装在容器支架上方，并且包括（1）针筒，其包括用于穿透可再密封塞子并将物质通过针引入容器的针，用于将针筒安装在歧管上的针座，以及 可拆卸地联接到针座的针罩，用于在从歧管运输，安装和/或移除针筒期间覆盖针头，并且当将针筒安装到歧管上时可从针筒上移除。 歧管还包括用于加热塞子的针穿入区域的热源，并且进而密封塞子中的针孔。

    Syringe and reconstitution syringe
    140.
    发明申请
    Syringe and reconstitution syringe 有权
    注射器和重建注射器

    公开(公告)号：US20070156102A1

    公开(公告)日：2007-07-05

    申请号：US11714004

    申请日：2007-03-05

    Applicant: Daniel Py

    Inventor： Daniel Py

    IPC: A61M5/315

    CPC classification number: A61M5/3129 ,  A61J1/2041 ,  A61J1/2044 ,  A61J1/2055 ,  A61J1/2093 ,  A61M5/1782 ,  A61M5/284 ,  A61M2005/3123

    Abstract: A syringe and a reconstitution syringe are provided for the delivery of controlled doses of any of numerous different sterile substances, such as vaccines, medicaments, pharmaceutical preparations, cosmetics, and food products. A plunger of the syringe defines a resealable stopper frictionally and slidably received within a hollow syringe body for dispensing the medicament or other substance through a dispensing tip of the syringe upon movement of the plunger. The resealable stopper defines a heat-sealable portion to allow the stopper to be penetrated by a needle or other filling device to fill the syringe with a medicament or other substance, and in turn allow the hole remaining upon withdrawal of the needle to be heat sealed by transmission of laser energy thereon. The plunger assembly further defines a plurality of cam-like members that each engage and cooperate with a respective helical path of steps formed on the inner wall of the syringe body to provide stepwise movement of the plunger and, in turn, precise metering of the substance dispensed therefrom. A reconstitution syringe defines within a syringe body plural compartments, wherein each compartment stores a respective component of a multi-component medicament or other preparation. An elastomeric plug is coupled to the plunger and connected between the two compartments to prevent intermixing of the components. Upon moving the plunger, the plug is released to thereby place the compartments in fluid communication with each other, and to facilitate intermixing of the components upon shaking the syringe.

    Abstract translation: 提供注射器和重组注射器用于递送受控剂量的许多不同的无菌物质，例如疫苗，药物，药物制剂，化妆品和食品中的任何一种。 注射器的柱塞限定了摩擦并可滑动地容纳在中空注射器主体内的可再密封塞子，用于在柱塞移动时通过注射器的分配尖端分配药物或其它物质。 可重新密封的止动件限定了可热封部分，以允许止动器被针或其他填充装置穿透，以用药物或其它物质填充注射器，并且进而允许在针头被热封时提供剩余的孔 通过在其上传输激光能量。 柱塞组件还限定多个凸轮状构件，每个凸轮状构件与形成在注射器主体的内壁上的步骤的相应螺旋路径接合并配合，以提供柱塞的逐步运动，并且进而精确地计量物质 从中分配。 重建注射器在注射器主体内限定多个隔室，其中每个隔室存储多组分药物或其它制剂的相应组分。 弹性塞连接到柱塞并连接在两个隔室之间以防止部件的混合。 在移动柱塞时，塞子被释放，从而将隔间彼此流体连通，并且有助于在振动注射器时组件的混合。

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