公开(公告)号：US20120215175A1

公开(公告)日：2012-08-23

申请号：US13360485

申请日：2012-01-27

申请人： Clifton A. Alferness ,  John M. Adams

发明人： Clifton A. Alferness ,  John M. Adams

IPC分类号： A61M5/142

CPC分类号： A61M5/1424 ,  A61M5/1454 ,  A61M2005/1405

摘要： A fully manually powered infusion device provides both basal and bolus delivery of a liquid medicament to a patient. In some embodiments, the device includes a main reservoir that supplies the liquid medicament, an outlet port that delivers the liquid medicament to the patient, a basal dispenser that delivers a substantially constant flow of the liquid medicament to the outlet port, and a manually actuated bolus pump that delivers a bolus dose of the liquid medicament from the main reservoir to the outlet when actuated. The basal medicament supply delivers a volume of the liquid medicament from the main reservoir to the basal dispenser consonant with each actuation of the bolus pump.

摘要翻译： 完全手动输液装置提供液体药物到患者的基础和推注。 在一些实施例中，该装置包括供给液体药物的主储存器，将液体药物输送给患者的出口端口，将液体药物的基本上恒定的流量输送到出口的基础分配器，以及手动致动 推动泵，其在致动时将液体药物从主容器输送到出口。 基础药物供应器通过每次推动推注泵将一定体积的液体药物从主储存器输送到基础分配器辅助器。

公开(公告)号：US08246581B2

公开(公告)日：2012-08-21

申请号：US13150395

申请日：2011-06-01

申请人： John M. Adams ,  Brett J. Carter

发明人： John M. Adams ,  Brett J. Carter

IPC分类号： A61M1/00

CPC分类号： A61M5/14248 ,  A61M5/14244 ,  A61M5/1452 ,  A61M5/16881 ,  A61M39/22 ,  A61M39/223 ,  A61M2005/14252 ,  A61M2005/1426 ,  A61M2039/224

摘要： A wearable infusion device comprises a reservoir that holds a liquid medicament, an outlet port that delivers the liquid medicament to a patient, a pump that holds a volume of the liquid medicament received from the reservoir and displaces substantially all of the volume of the liquid medicament when actuated, and at least a first valve, a second valve, and a third valve. The valves establish fluid connection between the reservoir and the pump when in a first valve configuration and establish fluid connection between the pump and the outlet when in a second valve configuration. At least two of the valves isolate the outlet from the reservoir when the valves are in the first valve configuration.

摘要翻译： 一种可佩戴的输注装置包括容纳液体药物的储存器，将液体药物输送给患者的出口端口，其保持从储存器接收的液体药物的体积，并基本上移动液体药物的大部分体积 当被致动时，以及至少第一阀，第二阀和第三阀。 当处于第一阀构造时，阀在储存器和泵之间建立流体连接，并且当处于第二阀配置时，在泵和出口之间建立流体连接。 当阀处于第一阀配置中时，至少有两个阀将出口与储存器隔离。

公开(公告)号：US20120197389A1

公开(公告)日：2012-08-02

申请号：US13443709

申请日：2012-04-10

申请人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

发明人： Clifton A. Alferness ,  John M. Adams ,  Mark L. Mathis ,  David G. Reuter ,  Cruz Beeson ,  Leonard Kowalsky

IPC分类号： A61F2/24

CPC分类号： A61F2/2451 ,  A61F2250/001 ,  A61F2250/0059

摘要： An intravascular support device includes a support or reshaper wire, a proximal anchor and a distal anchor. The support wire engages a vessel wall to change the shape of tissue adjacent the vessel in which the intravascular support is placed. The anchors and support wire are designed such that the vessel in which the support is placed remains open and can be accessed by other devices if necessary. The device provides a minimal metal surface area to blood flowing within the vessel to limit the creation of thrombosis. The anchors can be locked in place to secure the support within the vessel.

摘要翻译： 血管内支持装置包括支撑件或再生线，近端锚和远端锚。 支撑线接合血管壁以改变邻近其中放置血管内支架的血管的组织的形状。 锚和支撑线被设计成使得放置支撑件的容器保持打开，并且如果需要可以被其他装置访问。 该装置为在血管内流动的血液提供最小的金属表面积，以限制血栓形成。 锚固件可以锁定到位以将支撑件固定在容器内。

公开(公告)号：US08226606B2

公开(公告)日：2012-07-24

申请号：US11906108

申请日：2007-09-28

申请人： John M. Adams ,  Brett J. Carter

发明人： John M. Adams ,  Brett J. Carter

IPC分类号： A61M1/00

CPC分类号： A61M5/1424 ,  A61M5/14248 ,  A61M5/1684 ,  A61M2039/009

摘要： A wearable infusion device comprises a reservoir that holds a liquid medicament, an outlet port that delivers the liquid medicament to a patient, a pump that delivers a volume of the liquid medicament from the reservoir to the outlet when actuated, and a tactile indicator representing the volume of the liquid medicament delivered to the outlet with each actuation of the pump.

摘要翻译： 一种可佩戴的输注装置包括容纳液体药物的储存器，将液体药物输送给患者的出口端口;当被致动时将液体药物从容器输送到出口的泵，以及表示 在泵的每个致动下输送到出口的液体药物的体积。

公开(公告)号：US08114064B2

公开(公告)日：2012-02-14

申请号：US11705812

申请日：2007-02-12

申请人： Clifton A. Alferness ,  John M. Adams ,  Daniel Hawkins

发明人： Clifton A. Alferness ,  John M. Adams ,  Daniel Hawkins

IPC分类号： A61K9/22 ,  A61M5/20 ,  A61M1/00

CPC分类号： A61M5/1452 ,  A61M5/1408 ,  A61M5/14248 ,  A61M5/14526 ,  A61M5/1454 ,  A61M5/16881 ,  A61M2005/1405 ,  A61M2005/1426 ,  A61M2005/1585 ,  A61M2005/1587 ,  A61M2025/0266

摘要： A disposable infusion device comprises a base, a cannula arranged to extend from the base to beneath the patient's skin to deliver a liquid medicament to the patient, and a source arranged to provide the cannula with a liquid medicament. The source comprises a piston pump.

摘要翻译： 一次性输注装置包括基部，套管，其布置成从基部延伸到患者皮肤下方，以将液体药物递送到患者;以及源，布置成为套管提供液体药物。 源包括活塞泵。

公开(公告)号：US20100286602A1

公开(公告)日：2010-11-11

申请号：US12435996

申请日：2009-05-05

申请人： Brett J. Carter ,  John M. Adams

发明人： Brett J. Carter ,  John M. Adams

IPC分类号： A61M5/168 ,  A61M5/145

CPC分类号： A61M5/14244 ,  A61M5/1424 ,  A61M5/1452 ,  A61M5/16854 ,  A61M2039/0205

摘要： A wearable infusion device comprises a reservoir that holds a liquid medicament, an outlet that delivers the liquid medicament to a patient, and a pump that displaces a volume of the liquid medicament to the outlet when actuated. The device further includes a lock-out that disables actuation of the device responsive to a predetermined condition of the device. The lock-out is resettable.

摘要翻译： 可穿戴输注装置包括容纳液体药物的储存器，将液体药物输送给患者的出口，以及在致动时使一定体积的液体药物移动到出口的泵。 该装置还包括锁定，其响应于装置的预定条件禁用装置的致动。 锁定可重置。

公开(公告)号：US07713258B2

公开(公告)日：2010-05-11

申请号：US12205655

申请日：2008-09-05

申请人： John M. Adams ,  Clifton A. Alferness

发明人： John M. Adams ,  Clifton A. Alferness

IPC分类号： A61M31/00

CPC分类号： A61M5/14248 ,  A61M5/425 ,  A61M2005/1405 ,  A61M2005/1585

摘要： A device and method facilitates the forming of a skin fold during deployment of a cannula. The device may be a disposable infusion device and the method comprises adhering, to a skin surface, a base member having a port for receiving a cannula, forming a skin fold having skin surfaces sloping away from opposite sides of the base member, driving a cannula through the port of the base member while maintaining the skin fold, and releasing the skin fold. To facilitate the forming of the skin fold, the device comprises a base having a base surface and a flexible layer member. The flexible layer member has a first surface adjacent the base surface and a second surface adapted to be adhered to a patient's skin. The first surface has a first portion adhered to a portion of the base surface and a second portion adherable to the base surface.

摘要翻译： 装置和方法有助于在插管期间形成皮肤褶皱。 该装置可以是一次性输注装置，并且该方法包括将具有用于接收套管的端口的基部构件粘附到皮肤表面，形成具有从基部构件的相对侧倾斜的皮肤表面的皮肤褶皱，驱动套管 通过基底构件的端口，同时保持皮肤折叠，并释放皮肤褶皱。 为了促进皮肤褶皱的形成，该装置包括具有基底表面和柔性层部件的基部。 柔性层构件具有邻近基底表面的第一表面和适于粘附到患者皮肤的第二表面。 第一表面具有粘附到基部表面的一部分的第一部分和可粘附到基底表面的第二部分。

公开(公告)号：US20100030243A1

公开(公告)日：2010-02-04

申请号：US12460510

申请日：2009-07-18

申请人： Steve G. Baker ,  Brett J. Carter ,  Stefan J.M. Kraemer ,  Clifton A. Alferness ,  John M. Adams

发明人： Steve G. Baker ,  Brett J. Carter ,  Stefan J.M. Kraemer ,  Clifton A. Alferness ,  John M. Adams

IPC分类号： A61B17/08

CPC分类号： A61B17/0401 ,  A61B17/0469 ,  A61B17/064 ,  A61B17/068 ,  A61B2017/00827 ,  A61B2017/0409 ,  A61B2017/0414 ,  A61B2017/0419

摘要： Tissue fasteners carried on a tissue piercing deployment wire fasten tissue layers of a mammalian body together. The fasteners include a first member, a second member, and a connecting member extending between the first and second members. The first and second members are substantially parallel to each other. The fasteners may be deployed in limited spaces and in various applications including the restoration of a gastroesophageal flap valve.

摘要翻译： 携带在组织穿刺部署线上的组织紧固件将哺乳动物身体的组织层紧固在一起。 紧固件包括第一构件，第二构件和在第一构件和第二构件之间延伸的连接构件。 第一和第二构件基本上彼此平行。 紧固件可以在有限的空间和各种应用中部署，包括恢复胃食管瓣阀。

公开(公告)号：US20080249538A1

公开(公告)日：2008-10-09

申请号：US12079414

申请日：2008-03-25

申请人： Stefan J.M. Kraemer ,  John M. Adams ,  Stephen T. Vincent

发明人： Stefan J.M. Kraemer ,  John M. Adams ,  Stephen T. Vincent

IPC分类号： A61B17/00

CPC分类号： A61B17/068 ,  A61B17/00234 ,  A61B17/0644 ,  A61B17/07207 ,  A61B2017/003 ,  A61B2017/00827 ,  A61B2017/00867 ,  A61B2017/07214 ,  A61B2017/2905 ,  A61B2017/2926 ,  A61B2017/306

摘要： The invention provides a device, assembly, and method for transoral endoscopic restoration of a gastroesophageal flap valve. The invention also provides a self-steering and self-closing tissue fixation device for tissue fixation, and an invaginator device for gripping and maneuvering tissue. The restoration device includes a longitudinal member arranged for transoral placement into a stomach, a tissue shaper carried on the longitudinal member that causes stomach tissue to assume a shape related to a gastroesophageal flap, and a tissue fixation device that maintains the shaped stomach tissue in a shape approximating a gastroesophageal flap. The tissue shaper may include a mold. The device may include the invaginator device for gripping and maneuvering esophageal tissue to aid restoration of the gastroesophageal flap, and may include the tissue fixation device.

公开(公告)号：US20080119790A1

公开(公告)日：2008-05-22

申请号：US11604166

申请日：2006-11-22

申请人： Daniel Hawkins ,  Brett J. Carter ,  John M. Adams

发明人： Daniel Hawkins ,  Brett J. Carter ,  John M. Adams

IPC分类号： A61M25/00

CPC分类号： A61M5/158 ,  A61M5/14248 ,  A61M2005/1585 ,  A61M2205/583 ,  A61M2209/045

摘要： An infusion system includes a disposable wearable infusion device and a filler device. The disposable infusion device has a body arranged to be adhered to a patient's skin and a reservoir for holding a liquid medicant to be infused into the patient. The filler device is arranged to detachably receive the infusion device body and to transfer a volume of the liquid medicant to the infusion device reservoir. The filler device may be part of a service device arranged to detachably receive the infusion device and which also includes a cannula driver and a cannula for providing the infusion device with a cannula and deploying the cannula to beneath a patient's skin.

摘要翻译： 输液系统包括一次性佩戴式输液装置和填充装置。 一次性输注装置具有被布置成粘附到患者皮肤的本体和用于保持待注入患者体内的液体药剂的储存器。 填充装置布置成可拆卸地接收输注装置主体并将一定体积的液体药剂输送到输注装置储存器。 填充装置可以是布置成可拆卸地接收输注装置并且还包括插管驱动器和套管的服务装置的一部分，用于为输注装置提供插管并将插管展开到患者皮肤下方。