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公开(公告)号：US20130011471A1
公开(公告)日：2013-01-10
申请号：US13614111
申请日：2012-09-13
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号： A61K9/48 , A61P9/00 , A61P9/10 , A61P9/06 , A61P7/02 , A61P3/10 , A61P9/12 , A61P1/16 , A61P3/06 , A61K31/232 , A61P9/04
CPC分类号： A61K31/202 , A61K9/48 , A61K9/4825 , A61K9/4858 , A61K31/232 , A61K45/06
摘要： The present invention relates to, inter alia, pharmaceutical compositions comprising a polyunsaturated fatty acid and to methods of using the same to treat or prevent cardiovascular-related diseases.
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142.发明申请公开(公告)号：US20130005757A1
公开(公告)日：2013-01-03
申请号：US13540319
申请日：2012-07-02
申请人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号： A61K31/232 , A61K31/225 , A61K31/40 , A61P3/06 , A61K31/505
CPC分类号： A61K31/202 , A61K9/48 , A61K31/222 , A61K31/232 , A61K31/40 , A61K31/505 , A61K31/74 , A61K45/06 , A61K47/22 , A61K47/26 , A61K47/34 , A61K2300/00
摘要： The present invention relates to, inter alia, pharmaceutical compositions comprising EPA and one or more cardiovascular agents, and to therapeutic methods for treating various diseases and disorders using the same.
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公开(公告)号：US20130004568A1
公开(公告)日：2013-01-03
申请号：US13610247
申请日：2012-09-11
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
IPC分类号： A61K31/232 , A61K9/48 , A61P3/06
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号：US08318715B2
公开(公告)日：2012-11-27
申请号：US13282145
申请日：2011-10-26
申请人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
发明人： Mehar Manku , Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni
CPC分类号： A61K31/232 , A61K31/202 , A61K45/06 , G06F19/00
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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145.发明公开公开(公告)号：US20240024269A1
公开(公告)日：2024-01-25
申请号：US18168958
申请日：2023-02-14
发明人： Mehar Manku
IPC分类号： A61K31/202 , A61K31/232 , A61K31/455 , A61K45/06
CPC分类号： A61K31/202 , A61K31/232 , A61K31/455 , A61K45/06
摘要： The present invention relates to, inter alia, pharmaceutical compositions comprising eicosapentaenoic acid and/or derivatives thereof and nicotinic acid, to methods of manufacturing such compositions, and to therapeutic methods for treating carious diseases and disorders.
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146.发明公开公开(公告)号：US20230310372A1
公开(公告)日：2023-10-05
申请号：US18174345
申请日：2023-02-24
发明人： Rene Braeckman , William Stirtan , Paresh Soni
IPC分类号： A61K31/40 , A61K31/232
CPC分类号： A61K31/40 , A61K31/232
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of reducing triglycerides in a subject on atorvastatin therapy, the method comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号：US11712429B2
公开(公告)日：2023-08-01
申请号：US17097555
申请日：2020-11-13
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Jonathan Rowe
IPC分类号： A61K31/232 , A61K31/202 , A61K31/355 , A61K45/06 , A61P3/06 , A61P9/12 , A61P9/14 , A61K9/48
CPC分类号： A61K31/232 , A61K31/202 , A61K31/355 , A61K45/06 , A61P3/06 , A61P9/12 , A61P9/14 , A61K9/4875
摘要： In various embodiments, the present invention provides pharmaceutical compositions and methods for treating cardiovascular-related disease.
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148.发明申请公开(公告)号：US20220362200A1
公开(公告)日：2022-11-17
申请号：US17275576
申请日：2019-08-15
发明人： Craig Granowitz , Sephy Philip
IPC分类号： A61K31/232 , A61P9/10
摘要： In various embodiments, the present disclosure provides methods of diagnosing a need for peripheral arterial revascularization and/or reducing a need for peripheral arterial revascularization in a subject by administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
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公开(公告)号：US20220323395A1
公开(公告)日：2022-10-13
申请号：US17746625
申请日：2022-05-17
发明人： Rene Braeckman , William Stirtan , Paresh Soni
IPC分类号： A61K31/232 , A61K31/505 , A61K31/366 , A61K45/06 , A61K31/40
摘要： In various embodiments, the present invention provides methods of treating and/or preventing cardiovascular-related disease and, in particular, a method of blood lipid therapy comprising administering to a subject in need thereof a pharmaceutical composition comprising eicosapentaenoic acid or a derivative thereof.
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公开(公告)号：US11464757B2
公开(公告)日：2022-10-11
申请号：US17148409
申请日：2021-01-13
发明人： Ian Osterloh , Pierre Wicker , Rene Braeckman , Paresh Soni , Mehar Manku
IPC分类号： A61K31/202 , A61K31/232 , A61P9/10 , C07C57/03 , A61P3/06 , A61K31/366 , A61K31/40 , A61K31/505 , A61K9/48
摘要： In various embodiments, the present invention provides compositions and methods for treating and/or preventing cardiovascular-related diseases in subject in need thereof.
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