Imidazopyridine derivatives as phosphodiesterase VII inhibitors
    161.
    发明授权
    Imidazopyridine derivatives as phosphodiesterase VII inhibitors 失效
    咪唑并吡啶衍生物作为磷酸二酯酶VII抑制剂

    公开(公告)号:US06613778B1

    公开(公告)日:2003-09-02

    申请号:US10129274

    申请日:2002-05-03

    CPC classification number: C07D471/04

    Abstract: Compounds of the formula I in which R1 denotes CONR4R5, R2 denotes H or A, R4 and R5, independently of one another, each denote H or A1, R3 denotes Hal, Hal denotes F, Cl, Br or I, A denotes alkyl having 1-4 carbon atoms, A1 denotes alkyl having 1-10 carbon atoms, X denotes alkylene having 1-4 carbon atoms, in which an ethylene group may also be replaced by a double or triple bond, and their physiologically acceptable salts and/or solvates, as phosphodiesterase VII inhibitors, and their use for the preparation of a medicament.

    Abstract translation: R1表示CONR4R5的式Iin的化合物,R2表示H或A,R4和R5彼此独立地表示H或A1,R3表示Hal,Hal表示F,Cl,Br或I,A表示具有1- 4个碳原子,A1表示具有1-10个碳原子的烷基,X表示具有1-4个碳原子的亚烷基,其中亚乙基也可以被双键或三键替代,以及它们的生理上可接受的盐和/或溶剂合物, 作为磷酸二酯酶VII抑制剂,及其用于制备药物的用途。

    Arylalkanoylpyridazines
    162.
    发明授权
    Arylalkanoylpyridazines 失效
    芳基烷酰基哒嗪

    公开(公告)号:US06417188B1

    公开(公告)日:2002-07-09

    申请号:US09719467

    申请日:2000-12-13

    CPC classification number: C07D405/04 C07D237/04

    Abstract: Arylalkanoylpyridazine derivatives of the formula I and their physiologically acceptable salts and solvates, in which R1, R2, Q and B have the meanings indicated in Claim 1, show an inhibition of phosphodiesterase IV and can be employed for the treatment of asthma, chronic bronchitis, atopic dermatitis, psoriasis and other skin diseases, inflammatory diseases, autoimmune disorders, such as, for example, rheumatoid arthritis, multiple sclerosis, Crohn's disease, diabetes mellitus or ulcerative colitis, osteoporosis, transplant rejection reactions, cachexia, tumor growth or tumor metastases, sepsis, memory disorders, atherosclerosis and AIDS.

    Abstract translation: 式I的芳基烷酰基哒嗪衍生物及其生理上可接受的盐和溶剂合物,其中R 1,R 2,Q和B具有权利要求1所示的含义,显示了磷酸二酯酶IV的抑制,并且可用于治疗哮喘,慢性支气管炎,特应性皮炎 ,牛皮癣和其它皮肤疾病,炎性疾病,自身免疫性疾病,例如类风湿性关节炎,多发性硬化,克罗恩病,糖尿病或溃疡性结肠炎,骨质疏松症,移植排斥反应,恶病质,肿瘤生长或肿瘤转移,败血症, 记忆障碍,动脉粥样硬化和艾滋病。

    Clock generator and synchronizing method
    163.
    发明授权
    Clock generator and synchronizing method 失效
    时钟发生器和同步方法

    公开(公告)号:US06181175B2

    公开(公告)日:2001-01-30

    申请号:US09340673

    申请日:1999-06-29

    Applicant: Michael Wolf

    Inventor: Michael Wolf

    Abstract: Network elements of a synchronous digital communications system have a clock generator for generating a clock signal locked to an input signal. Such a clock generator comprises a tunable oscillator (OSC) and a phase comparator (PK) for comparing the phase of the input signal (IN) with the phase of the clock signal (CLK) and for generating a correction signal which serves to tune the oscillator (OSC). To avoid phase transients due to interruptions and disturbances in the input signal (IN), means (WD) are provided for determining an expectancy window, for deciding whether the correction signal lies within the expectancy window, and for tuning the oscillator with the correction signal if the correction signal lies within the expectancy window.

    Abstract translation: 同步数字通信系统的网络元件具有用于产生锁定到输入信号的时钟信号的时钟发生器。 这种时钟发生器包括可调谐振荡器(OSC)和用于将输入信号(IN)的相位与时钟信号(CLK)的相位进行比较的相位比较器(PK),并用于产生用于调谐 振荡器(OSC)。 为了避免由于输入信号(IN)中的中断和干扰引起的相位瞬变,提供了用于确定预期窗口的装置(WD),用于确定校正信号是否在预期窗口内,以及用校正信号调谐振荡器 如果校正信号位于预期窗口内。

    Process and device for determining a pressure value
    164.
    发明授权
    Process and device for determining a pressure value 失效
    用于确定压力值的过程和装置

    公开(公告)号:US6123395A

    公开(公告)日:2000-09-26

    申请号:US11487

    申请日:1998-02-02

    CPC classification number: B60T8/40 B60T8/4059

    Abstract: A method and a device for determining a pressure variable, in particular in a braking system having a delivery pump. The differential pressure between a first line and a second line is determined using as a baseline a variable which represents a measure for the speed of the delivery pump.

    Abstract translation: PCT No.PCT / DE96 / 01246 Sec。 371日期1998年2月2日 102(e)1998年2月2日PCT PCT 1996年7月11日PCT公布。 公开号WO97 / 06038 日期1997年2月20日一种用于确定压力变量的方法和装置,特别是在具有输送泵的制动系统中。 使用代表输送泵速度的量度的变量作为基准来确定第一线和第二线之间的压差。

    Device for printing to stock standing on edge
    165.
    发明授权
    Device for printing to stock standing on edge 失效
    用于打印的设备站在边缘

    公开(公告)号:US5880747A

    公开(公告)日:1999-03-09

    申请号:US791630

    申请日:1997-01-31

    CPC classification number: G07B17/00467 B41J13/12

    Abstract: A device for printing stock standing on one edge, in particular a piece of mail in a postage meter and/or addressing machine, includes a guide plate for the stock which is inclined relative to the vertical and has a recessed region for a printing device. A rotating conveyor has a conveying plane which extends orthogonal to the guide plate and on which the stock stands on one edge and is transported in one direction while resting against the guide plate. The recessed region includes at least one cutout and a region of the guide plate downstream of the cutout is so far recessed from a bearing surface for the stock that there is no contact with the latter in this location. This ensures sufficient penetration time for the ink and prevents smearing of the printed image. The printing device is an ink jet printing device which is stationary during printing and which has a nozzle plane that extends parallel to the guide plate. The guide plate is inclined a maximum of 45.degree. from vertical. The conveyor runs continuously. This structure simplifies transport of the piece of mail, improves the printing technology and ensures a clean printed image at high throughput.

    Abstract translation: 一种用于打印在一个边缘上的纸张的装置,特别是邮资计费器和/或寻址机中的邮件,包括一个相对于垂直方向倾斜并且具有用于打印装置的凹进区域的库存引导板。 旋转输送机具有与导板垂直延伸的输送平面,并且在一个边缘上放置坯料并沿着一个方向输送,同时靠在引导板上。 凹陷区域包括至少一个切口,并且在切口下游的引导板的区域远离用于库存的支承表面凹陷,在该位置处不与后者接触。 这确保了足够的油墨穿透时间并防止印刷图像的污迹。 打印装置是在打印期间静止的喷墨打印装置,并且具有平行于引导板延伸的喷嘴平面。 导板最大倾斜45度。 输送机连续运行。 这种结构简化了邮件的传输,改善了打印技术,并确保了高吞吐量的清晰打印图像。

    Receiver for bandspread signals, particularly GPS receiver
    169.
    发明授权
    Receiver for bandspread signals, particularly GPS receiver 失效
    接收机用于带宽信号,特别是GPS接收机

    公开(公告)号:US5016257A

    公开(公告)日:1991-05-14

    申请号:US323570

    申请日:1989-03-13

    Abstract: Receivers for bandspread signals have a carrier PLL (20) for the carrier frequency and phase and a code PLL (20, 30 . . . 34) for the code frequency and phase. To be able to receive even very noisy signals, the carrier PLL, in particular, must have a very narrow bandwidth. This results in a very narrow capture range.According to the invention, instead of employing a complicated search strategy, advantage is taken of the fact that the code PLL locks in more easily. A signal is taken from the code PLL which indicates the difference between the desired value and the actual value of the code frequency. This signal is fed as an additional control signal to the carrier PLL.

    Abstract translation: 用于带宽信号的接收机具有用于载波频率和相位的载波PLL(20)和用于码频率和相位的码PLL(20,30 ... 34)。 为了能够接收甚至非常嘈杂的信号,载波PLL特别地必须具有非常窄的带宽。 这导致非常窄的捕获范围。 根据本发明,代替使用复杂的搜索策略,优点在于代码PLL更容易锁定。 从代码PLL获取信号,该代码PLL指示期望值与代码频率的实际值之间的差。 该信号作为附加控制信号馈送到载波PLL。

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