公开(公告)号：US20090088784A1

公开(公告)日：2009-04-02

申请号：US12240101

申请日：2008-09-29

申请人： Charles DeBoer ,  Matthew McCormick ,  Prashant R. Bhadri ,  Aaron Barnes ,  Ralph Kerns ,  Mark S. Humayun

发明人： Charles DeBoer ,  Matthew McCormick ,  Prashant R. Bhadri ,  Aaron Barnes ,  Ralph Kerns ,  Mark S. Humayun

IPC分类号： A61B17/32

CPC分类号： A61B17/32002 ,  A61B17/22031 ,  A61B17/320783 ,  A61B2017/00544 ,  A61B2017/320028 ,  A61B2017/32004 ,  A61F9/007 ,  A61F9/00736

摘要： Apparatus, systems, and devices are described that utilize an adjustable biological tissue cutting handpiece that is based on selectable settings. The biological tissue cutting handpiece includes a cutter tip that allows multiple duty cycles as well as multiple port configurations. For example, when working next to the retina, the port could be adjusted to be a smaller size, allowing delicate membrane dissection. When working near or in less sensitive tissue, e.g. the center of the eye, the port could be wide open. The port aperture size can be independent of cut speed, allowing a surgeon to work at high speed both next to the retina and away from the retina. High speeds have been shown to have increased tissue (e.g., vitreous) removal, e.g., in 25 and 23-gauge instruments. Duty cycle is not necessarily dependent on cut speed, allowing high cutter performance and varied flow characteristics.

摘要翻译： 描述了使用基于可选择设置的可调节生物组织切割手持件的装置，系统和装置。 生物组织切割手持件包括允许多个占空比以及多个端口配置的切割器尖端。 例如，当在视网膜旁边工作时，可以将端口调整为更小的尺寸，从而允许精细的膜剥离。 当靠近或较不敏感的组织工作时，例如， 眼睛的中心，港口可以大开。 端口孔径尺寸可以独立于切割速度，允许外科医生在视网膜旁边和远离视网膜的高速下工作。 已经显示高速度具有增加的组织（例如，玻璃体）去除，例如在25和23号仪器中。 占空比不一定取决于切割速度，允许高切割性能和不同的流动特性。

公开(公告)号：US20050059956A1

公开(公告)日：2005-03-17

申请号：US10823089

申请日：2004-04-12

申请人： Signe Varner ,  Eugene Dejuan ,  Terry Shelley ,  Aaron Barnes ,  Mark Humayun

发明人： Signe Varner ,  Eugene Dejuan ,  Terry Shelley ,  Aaron Barnes ,  Mark Humayun

IPC分类号： A61F9/007 ,  A61B17/00 ,  A61F9/00 ,  A61K9/00 ,  A61K9/22 ,  A61K45/00 ,  A61L31/00 ,  A61P27/02 ,  A61M31/00

CPC分类号： A61K9/0051 ,  A61B2017/00867 ,  A61F9/0017

摘要： An therapeutic agent delivery device that can allows is particularly suitable for delivery of a therapeutic agent to limited access regions, such as the posterior chamber of the eye and inner ear. Preferred devices of the invention are minimally invasive, refillable and may be easily fixed to the treatment area. Preferred delivery devices of the invention also include those that comprise a non-linear shaped body member body housing one or more substances and a delivery mechanism for the sustained delivery of the one or more substances from the non-linear shaped body member to the patient.

摘要翻译： 可以允许的治疗剂递送装置特别适合于将治疗剂递送到有限的进入区域，例如眼睛的后室和内耳。 本发明的优选装置是微创的，可再填充的并且可以容易地固定到治疗区域。 本发明的优选输送装置还包括包含一个或多个物质的非线性形状的身体构件体和用于将一种或多种物质从非线性形状的身体构件持续递送至患者的输送机构的输送装置。