公开(公告)号：US6146357A

公开(公告)日：2000-11-14

申请号：US307092

申请日：1999-05-07

Applicant: Bruce Addis

Inventor： Bruce Addis

IPC: A61F2/958 ,  A61M29/00

CPC classification number: A61M25/10184 ,  A61M25/1018 ,  A61M25/10187 ,  A61M2025/0001 ,  A61M2025/1059 ,  A61M2025/1068

Abstract: The invention provides a device having first and second balloons. Each of the first and second balloons communicates with an inflation lumen. A differential pressure gauge communicates with both inflation lumens. Each of the inflation lumens also communicates independently with a pump for inflating the balloon. The pressure gauge may include a shut-off valve for terminating inflation in the second balloon when the pressure within the first balloon exceeds the pressure in the second balloon. The pressure gauge may also include a pressure limiter. Methods of using the devices for measuring diameter and pressure of a balloon occluder deployed in a vessel or body cavity are disclosed.

公开(公告)号：US20240074764A1

公开(公告)日：2024-03-07

申请号：US18241582

申请日：2023-09-01

Applicant: Bruce Addis

Inventor： Bruce Addis

IPC: A61B17/12

CPC classification number: A61B17/12136 ,  A61B17/12109

Abstract: Exemplary occlusion and molding devices and methods involve the use of an expandable balloon. Methods of sealing an aortic side branch in a patient can include advancing an occlusion device within the aorta, positioning a toroidal balloon of the occlusion device adjacent to the aortic side branch, and inflating the balloon to prevent peripheral blood flow from the aorta into the aortic side branch while a central aperture of the balloon allows descending aortic blood flow therethrough. Methods of molding a stent against an interior surface of a vessel of a patient can include advancing a molding device within the vessel, positioning a toroidal balloon of the molding device at least partially withing the stent, and inflating the balloon to exert force to the stent thus dilating the stent and molding it to the interior of the vessel while a central aperture of the balloon allows blood flow therethrough.

公开(公告)号：US08409249B2

公开(公告)日：2013-04-02

申请号：US12079049

申请日：2008-03-24

Applicant: Olexander Hnojewyj ,  Bruce Addis ,  Daniel Browne ,  David Cheung

Inventor： Olexander Hnojewyj ,  Bruce Addis ,  Daniel Browne ,  David Cheung

IPC: A61B17/08

CPC classification number: A61B17/0057 ,  A61B17/00491 ,  A61B2017/00004 ,  A61B2017/00495 ,  A61B2017/00637 ,  A61B2017/0065 ,  A61B2017/00654 ,  A61B2017/00663

Abstract: Systems and methods employ functional instruments to close incisions and wounds using a suture knot in combination with a biocompatible material composition. The systems and methods are well suited for use, for example, at a vascular puncture site following a vascular access procedure.

公开(公告)号：US06676683B1

公开(公告)日：2004-01-13

申请号：US09721151

申请日：2000-11-17

Applicant: Bruce Addis

Inventor： Bruce Addis

IPC: A61M2900

CPC classification number: A61F2/013 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0067 ,  A61F2230/0093

Abstract: A filter device for temporary placement of a filter in an artery or vein is disclosed. The device includes an expandable filter mounted on a distal end of a catheter. The filter comprises a plurality of circumferentially adjacent porous segments that are arranged generally about the surface of a cone having an open base, and the segments are engaged to one another by means, such as a hook. The filter conforms to the interior of a vessel wall when expanded and contracts to a consistent diameter without bunching when stowed. Methods of using the filter device to entrap and remove embolic material from a vessel during endovascular procedures are also disclosed.

Abstract translation: 公开了一种用于将过滤器临时放置在动脉或静脉中的过滤装置。 该装置包括安装在导管的远端上的可扩张过滤器。 过滤器包括多个周向相邻的多孔段，其通常围绕具有开放底座的锥体的表面布置，并且通过诸如钩的装置将段彼此接合。 过滤器在膨胀时符合血管壁的内部，并收缩到一致的直径，而不会在收起时聚束。 还公开了使用过滤装置在血管内手术期间从血管中捕获和去除栓塞物质的方法。

公开(公告)号：US06626866B1

公开(公告)日：2003-09-30

申请号：US09614425

申请日：2000-07-12

Applicant: Bruce Addis

Inventor： Bruce Addis

IPC: A61M100

CPC classification number: A61B5/0084 ,  A61M1/008 ,  A61M1/3653 ,  A61M1/3659 ,  A61M1/3666 ,  A61M25/003 ,  A61M2025/0031 ,  A61M2025/0037

Abstract: A probe having the ability to deliver cardioplegia solution to the coronary sinus under direct visualization and to provide venous drainage from the right atrium for cardiopulmonary bypass. The probe has an elongate tubular member, including a distal end, a proximal end, and a lumen. A membrane, optionally perforated, mounted within the lumen of the tubular member partitions the lumen and is removable or penetrable by a cardioplegia catheter. The distal end comprises a toroidal balloon or a circumferential recessed vacuum manifold. A vacuum port communicates with the distal end of the tubular member or the vacuum manifold. Methods of using the cardioplegia access view probe for catheterization of the coronary sinus and for venous return as herein described are also disclosed.

Abstract translation: 探针具有在直接观察下将心麻痹液提供给冠状窦的能力，并为右心房提供心肺旁路静脉引流。 探针具有细长的管状构件，包括远端，近端和内腔。 安装在管状构件的内腔中的任选穿孔的隔膜分隔内腔并且可由心麻痹导管移除或穿透。 远端包括环形球囊或圆周凹陷的真空歧管。 真空口与管状部件或真空歧管的远端连通。 还公开了如本文所述的使用用于导管冠状动脉窦和静脉回流的心麻痹检视探针的方法。

公开(公告)号：US06494895B2

公开(公告)日：2002-12-17

申请号：US09844895

申请日：2001-04-26

Applicant: Bruce Addis

Inventor： Bruce Addis

IPC: A61M2900

CPC classification number: A61F2/013 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/221 ,  A61B2017/1205 ,  A61B2017/2215 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/008

Abstract: An expansion frame system for deploying medical devices in a patient's body cavity. The system typically includes an inner wire disposed within a lumen of an outer wire. Distal ends of the inner and outer wires are attached to a substantially circular frame at first and second points. During use, the outer wire is displaced relative to the inner wire, causing the circular frame to rotate about an axis perpendicular to the line defined by the first and second points. Medical devices, such as a filter, a stent, an occluder or a manometer, can be mounted on the circular frame. The diameter of the expansion frame can be varied to achieve optimal contact with the luminal wall of the body cavity. Methods of using the expansion frame system for temporary or permanent placement of a medical device is disclosed.

Abstract translation: 一种用于在患者体腔中部署医疗装置的扩展框架系统。 该系统通常包括设置在外部线的内腔内的内部线。 内部和外部电线的末端在第一和第二点附接到基本圆形的框架。 在使用期间，外部线材相对于内部线材移位，使得圆形框架围绕垂直于由第一和第二点限定的线条的轴线旋转。 诸如过滤器，支架，闭塞器或压力计的医疗装置可以安装在圆形框架上。 可以改变膨胀框架的直径以实现与体腔的腔壁的最佳接触。 公开了使用扩展框架系统临时或永久性地放置医疗装置的方法。

公开(公告)号：US5935135A

公开(公告)日：1999-08-10

申请号：US862422

申请日：1997-05-23

Applicant: John Bramfitt ,  Bruce Addis

Inventor： John Bramfitt ,  Bruce Addis

IPC: A61F2/82 ,  A61F11/00

CPC classification number: A61F2/958 ,  A61F2002/826 ,  A61F2002/9583

Abstract: A balloon delivery system for deploying stents including a balloon catheter, and a stent fixedly positioned on the balloon portion of the balloon catheter by at least one protrusion such as annular cuff formed around the balloon. The balloon can include two or more continuous or discontinuous cuffs formed along the balloon which maintain one or more stents in position on the balloon. The protrusion can be created from excess material of the balloon which is configured in a desired fashion around the balloon to form the protrusion. The protrusion improves the fixation of the stent on the balloon catheter until the balloon is inflated to deploy the stent within a body lumen. The protrusion restrains the movement of the stent without a significant change in the overall profile of the balloon delivery system. The protrusion or protrusions can be provided as a series of circumferentially spaced-apart projections, a C-shaped annular cuff, a continuous annular cuff or two or more axially spaced-apart projections or cuffs.

Abstract translation: 一种用于展开支架的气囊输送系统，所述支架包括气囊导管和固定地定位在气囊导管的球囊部分上的支架，所述支架通过至少一个突起例如形成在所述气囊周围的环形袖带。 气囊可以包括沿气囊形成的两个或更多个连续或不连续的袖口，其将一个或多个支架保持在气囊上的适当位置。 突起可以由围绕气球以期望的方式构造的气球的多余材料形成，以形成突起。 突起改善了支架在气囊导管上的固定，直到球囊膨胀以将支架展开在体腔内。 突出部限制了支架的运动，而球囊输送系统的整体轮廓没有显着变化。 突起或突起可以设置成一系列周向间隔开的突起，C形环形箍，连续环形箍或两个或更多个轴向间隔开的突起或箍。

公开(公告)号：US07608087B1

公开(公告)日：2009-10-27

申请号：US10293030

申请日：2002-11-12

Applicant: Bruce Addis

Inventor： Bruce Addis

IPC: A61M29/00

CPC classification number: A61F2/013 ,  A61B17/12022 ,  A61B17/12109 ,  A61B17/221 ,  A61B2017/1205 ,  A61B2017/2215 ,  A61F2002/018 ,  A61F2230/0006 ,  A61F2230/0008 ,  A61F2230/008

Abstract: An expansion frame system for deploying medical devices in a patient's body cavity. The system typically includes an inner wire disposed within a lumen of an outer wire. Distal ends of the inner and outer wires are attached to a substantially circular frame at first and second points. During use, the outer wire is displaced relative to the inner wire, causing the circular frame to rotate about an axis perpendicular to the line defined by the first and second points. Medical devices, such as a filter, a stent, an occluder or a manometer, can be mounted on the circular frame. The diameter of the expansion frame can be varied to achieve optimal contact with the luminal wall of the body cavity. Methods of using the expansion frame system for temporary or permanent placement of a medical device is disclosed.

公开(公告)号：US20080038313A1

公开(公告)日：2008-02-14

申请号：US11973526

申请日：2007-10-09

Applicant: Bruce Addis ,  Charles Milo ,  Olexander Hnojewyj

Inventor： Bruce Addis ,  Charles Milo ,  Olexander Hnojewyj

IPC: A61K31/74 ,  A61F2/06 ,  A61K9/00 ,  A61M31/00 ,  A61P17/02 ,  C07K1/107

CPC classification number: A61B17/0057 ,  A61B17/00491 ,  A61B2017/00004 ,  A61B2017/00495 ,  A61B2017/00637 ,  A61B2017/0065

Abstract: A method of treating tissue lyophilizes a biocompatible polymer having a functionality equal to or greater than three. The method provides a protein solution. The method mixes the protein solution with the lyophilized polymer to reconstitute the polymer and form a mixture, wherein, upon mixing, the protein solution and the polymer cross-link to form a material composition. The method applies the material composition to a tissue region. The biocompatible polymer can comprise, e.g., poly(ethylene glycol) PEG. The protein solution can comprise, e.g., albumin.

Abstract translation: 治疗组织的方法将具有等于或大于3的功能的生物相容性聚合物冻干。 该方法提供蛋白质溶液。 该方法将蛋白质溶液与冻干聚合物混合以重构聚合物并形成混合物，其中在混合时，蛋白质溶液和聚合物交联以形成材料组成。 该方法将材料组合物应用于组织区域。 生物相容性聚合物可以包括例如聚（乙二醇）PEG。 蛋白质溶液可以包含例如白蛋白。

公开(公告)号：US07279001B2

公开(公告)日：2007-10-09

申请号：US10141510

申请日：2002-05-08

Applicant: Bruce Addis ,  Charles Milo ,  Olexander Hnojewyj

Inventor： Bruce Addis ,  Charles Milo ,  Olexander Hnojewyj

IPC: A61B17/08 ,  A61D1/00

CPC classification number: A61B17/0057 ,  A61B17/00491 ,  A61B2017/00004 ,  A61B2017/00495 ,  A61B2017/00637 ,  A61B2017/0065

Abstract: Systems and methods convey a closure material into a catheter, e.g., to seal a puncture site in a blood vessel. The closure material comprises a mixture of first and second components, which, upon mixing, undergo a reaction to form solid closure material composition. The first component may be a lyophilized polyethylene glycol (PEG) material contained within a vial. The second component may be a buffered albumin solution plus water contained within a syringe. An applicator provides easy and effective mixing of the components and delivery of the mixture to the puncture site.

Abstract translation: 系统和方法将封闭材料输送到导管中，例如以密封血管中的穿刺部位。 封闭材料包括第一和第二组分的混合物，其在混合时经历反应以形成固体封闭材料组合物。 第一组分可以是包含在小瓶内的冻干聚乙二醇（PEG）材料。 第二组分可以是缓冲的白蛋白溶液和加在注射器内的水。 施用器提供容易且有效地混合组分并将混合物输送到穿刺部位。