公开(公告)号：US08143385B2

公开(公告)日：2012-03-27

申请号：US12353812

申请日：2009-01-14

Applicant: Viia Valge-Archer ,  Andrew James Williams ,  Deborah A. Young ,  Matthew J. Whitters ,  Mary Collins ,  Joann Witek

Inventor： Viia Valge-Archer ,  Andrew James Williams ,  Deborah A. Young ,  Matthew J. Whitters ,  Mary Collins ,  Joann Witek

IPC: C07H21/04 ,  A61K39/00 ,  C12N5/16 ,  H01N33/53

CPC classification number: C07K16/2866 ,  A61K2039/505 ,  C07K2317/56 ,  C07K2317/622

Abstract: The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-21 receptor (IL-21R). The antibodies can act as antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, transplant rejection, cancer, and other immune system disorders.

Abstract translation: 本申请提供了特异性结合人白细胞介素-21受体（IL-21R）的人抗体及其抗原结合片段。 抗体可以作为IL-21R活性的拮抗剂，从而调节一般的免疫应答，特别是由IL-21R介导的那些。 所公开的组合物和方法可用于例如诊断，治疗或预防炎性疾病，自身免疫疾病，过敏，移植排斥，癌症和其他免疫系统疾病。

公开(公告)号：US20090298167A1

公开(公告)日：2009-12-03

申请号：US12472209

申请日：2009-05-26

Applicant: Laird BLOOM ,  Davinder GILL ,  Yulia VUGMEYSTER ,  Deborah A. YOUNG ,  David LOWE ,  Viia VALGE-ARCHER

Inventor： Laird BLOOM ,  Davinder GILL ,  Yulia VUGMEYSTER ,  Deborah A. YOUNG ,  David LOWE ,  Viia VALGE-ARCHER

IPC: C12N5/10 ,  C07K14/00 ,  C07K16/18 ,  C07H21/00 ,  C12N15/74

CPC classification number: C07K14/54 ,  C07K16/2866 ,  C07K2317/21 ,  C07K2317/52 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/92

Abstract: The present invention provides binding proteins and antigen-binding fragments thereof that specifically bind to the human interleukin-21 receptor (IL-21R). The binding proteins can act as, e.g., antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used, e.g., in diagnosing and/or treating IL-21R-associated disorders, e.g., inflammatory disorders, autoimmune diseases, allergies, transplant rejection, cancer, and other immune system disorders.

Abstract translation: 本发明提供与人白细胞介素-21受体（IL-21R）特异性结合的结合蛋白及其抗原结合片段。 结合蛋白可以作为例如IL-21R活性的拮抗剂，从而调节一般的免疫应答，特别是由IL-21R介导的那些。 所公开的组合物和方法可用于例如诊断和/或治疗IL-21R相关疾病，例如炎症性疾病，自身免疫疾病，过敏反应，移植排斥反应，癌症和其他免疫系统疾病。

公开(公告)号：US10861104B1

公开(公告)日：2020-12-08

申请号：US13620460

申请日：2012-09-14

Applicant: Deborah A. Young

Inventor： Deborah A. Young

IPC: G06Q20/14 ,  G06Q40/00

Abstract: A computer-implemented system and method configure a payment processing system to interpret image data from scanned payment coupons. A screen display is generated for presentation to a recipient of payments, such as a business. The screen display shows a sample payment coupon. Configuration information is received that is generated based on user inputs. The user inputs designate a region of the sample payment coupon and define how scanned information in the designated region is to be interpreted.

公开(公告)号：US20120276102A1

公开(公告)日：2012-11-01

申请号：US13470500

申请日：2012-05-14

Applicant: Laird BLOOM ,  Davinder GILL ,  Yulia VUGMEYSTER ,  Deborah A. YOUNG ,  Margot O'TOOLE ,  Heath M. GUAY ,  Karissa K. ADKINS ,  Amy Arlene WEAVER ,  Sadhana JAIN ,  Maya ARAI

Inventor： Laird BLOOM ,  Davinder GILL ,  Yulia VUGMEYSTER ,  Deborah A. YOUNG ,  Margot O'TOOLE ,  Heath M. GUAY ,  Karissa K. ADKINS ,  Amy Arlene WEAVER ,  Sadhana JAIN ,  Maya ARAI

IPC: A61K39/395 ,  A61P29/00 ,  A61P37/08 ,  A61P35/00 ,  C12Q1/68 ,  A61P17/06 ,  A61P19/02 ,  G01N33/566 ,  G01N21/76 ,  A61P37/06 ,  A61P25/00

CPC classification number: G01N33/6869 ,  A61K38/00 ,  A61K2039/505 ,  C07K16/2866 ,  C07K2317/21 ,  C07K2317/56 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2319/30 ,  G01N2333/54

Abstract: The present invention provides binding proteins and antigen-binding fragments thereof, including human antibodies, that specifically bind to the human interleukin-21 receptor (IL-21R), and methods of using them. The binding proteins can act as, e.g., antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used, e.g., in diagnosing, treating, and/or preventing IL-21R-associated disorders, e.g., inflammatory disorders, autoimmune diseases, allergies, transplant rejection, and other immune system disorders.

Abstract translation: 本发明提供特异性结合人白细胞介素-21受体（IL-21R）的结合蛋白及其抗原结合片段，包括人抗体，以及使用它们的方法。 结合蛋白可以作为例如IL-21R活性的拮抗剂，从而调节一般的免疫应答，特别是由IL-21R介导的那些。 所公开的组合物和方法可以用于例如诊断，治疗和/或预防IL-21R相关疾病，例如炎性疾病，自身免疫疾病，过敏，移植排斥和其它免疫系统疾病。

公开(公告)号：US08163884B2

公开(公告)日：2012-04-24

申请号：US12472209

申请日：2009-05-26

Applicant: Laird Bloom ,  Davinder Gill ,  Yulia Vugmeyster ,  Deborah A. Young ,  David Lowe ,  Viia Valge-Archer

Inventor： Laird Bloom ,  Davinder Gill ,  Yulia Vugmeyster ,  Deborah A. Young ,  David Lowe ,  Viia Valge-Archer

IPC: C07K16/28 ,  A61K39/00 ,  A61K39/395 ,  C12P21/02

CPC classification number: C07K14/54 ,  C07K16/2866 ,  C07K2317/21 ,  C07K2317/52 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/92

Abstract: The present invention provides binding proteins and antigen-binding fragments thereof that specifically bind to the human interleukin-21 receptor (IL-21R). The binding proteins can act as, e.g., antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used, e.g., in diagnosing and/or treating IL-21R-associated disorders, e.g., inflammatory disorders, autoimmune diseases, allergies, transplant rejection, cancer, and other immune system disorders.

Abstract translation: 本发明提供与人白细胞介素-21受体（IL-21R）特异性结合的结合蛋白及其抗原结合片段。 结合蛋白可以作为例如IL-21R活性的拮抗剂，从而调节一般的免疫应答，特别是由IL-21R介导的那些。 所公开的组合物和方法可用于例如诊断和/或治疗IL-21R相关疾病，例如炎症性疾病，自身免疫疾病，过敏反应，移植排斥反应，癌症和其他免疫系统疾病。

公开(公告)号：US07495085B2

公开(公告)日：2009-02-24

申请号：US10798380

申请日：2004-03-12

Applicant: Viia Valge-Archer ,  Andrew James Williams ,  Deborah A. Young ,  Matthew J. Whitters ,  Mary Collins ,  Joann Witek

Inventor： Viia Valge-Archer ,  Andrew James Williams ,  Deborah A. Young ,  Matthew J. Whitters ,  Mary Collins ,  Joann Witek

IPC: C07K16/28 ,  A61K39/00 ,  A61K39/395 ,  C12P21/00

CPC classification number: C07K16/2866 ,  A61K2039/505 ,  C07K2317/56 ,  C07K2317/622

Abstract: The present application provides human antibodies and antigen binding fragments thereof that specifically bind to the human interleukin-21 receptor (IL-21R). The antibodies can act as antagonists of IL-21R activity, thereby modulating immune responses in general, and those mediated by IL-21R in particular. The disclosed compositions and methods may be used for example, in diagnosing, treating or preventing inflammatory disorders, autoimmune diseases, allergies, transplant rejection, cancer, and other immune system disorders.

Abstract translation: 本申请提供了特异性结合人白细胞介素-21受体（IL-21R）的人抗体及其抗原结合片段。 抗体可以作为IL-21R活性的拮抗剂，从而调节一般的免疫应答，特别是由IL-21R介导的那些。 所公开的组合物和方法可用于例如诊断，治疗或预防炎性疾病，自身免疫疾病，过敏，移植排斥，癌症和其他免疫系统疾病。

公开(公告)号：US07392935B2

公开(公告)日：2008-07-01

申请号：US11351457

申请日：2006-02-09

Applicant: Michael D. Byrne ,  Byron G. Chun ,  Art Molina ,  Frank S. Lee ,  Stephanie Sturgis-Griffith ,  Bipin M. Sahni ,  Gene Weisbord ,  Deborah A. Young

Inventor： Michael D. Byrne ,  Byron G. Chun ,  Art Molina ,  Frank S. Lee ,  Stephanie Sturgis-Griffith ,  Bipin M. Sahni ,  Gene Weisbord ,  Deborah A. Young

IPC: G06Q40/00

CPC classification number: G06Q20/042 ,  G06Q20/10 ,  G06Q20/102 ,  G06Q20/108 ,  G06Q20/1085 ,  G06Q40/00

Abstract: A browser plug-in to drive a device for securely transmitting documents in real-time over the Internet into an enterprise's computing environment is provided. Leveraging the Check Clearing for the 21st Century Act, a system and method for providing a browser plug-in that allows a bank customer to scan checks using a personal computer and deposit the checks via the browser to a bank account is provided.

Abstract translation: 提供了一种浏览器插件，用于驱动设备将文档通过Internet实时安全地传输到企业的计算环境中。 利用“21世纪检查清算法”，提供了一种提供浏览器插件的系统和方法，该插件允许银行客户使用个人计算机扫描支票，并通过浏览器将支票存入银行账户。