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公开(公告)号:US4288539A
公开(公告)日:1981-09-08
申请号:US16252
申请日:1979-02-28
IPC分类号: C12Q1/04 , C12Q1/12 , G01N33/569 , G01N33/571 , G01N33/00
CPC分类号: C12Q1/12 , C12Q1/04 , G01N33/56911 , G01N33/571 , Y10S435/81
摘要: Automated tests to evaluate the antibody titer of a sample by incubating a test sample, bacteria, and complement, and detecting bacterial growth in the incubated mixture, and to identify bacteria and its titer in a sample by incubating a test sample, bacterial antiserum, and complement, and detecting inhibition of bacterial growth in the incubated mixture. The automated tests lend themselves to diagnostic use and may be provided in the form of diagnostic test kits.
摘要翻译: 通过孵育测试样品,细菌和补体以及检测培养的混合物中的细菌生长来评估样品的抗体滴度的自动化测试,并通过孵育测试样品,细菌抗血清和样品来鉴定样品中的细菌及其滴度 补体,并检测孵育的混合物中细菌生长的抑制。 自动化测试适用于诊断用途,可以以诊断测试工具包的形式提供。
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公开(公告)号:US4147772A
公开(公告)日:1979-04-03
申请号:US880667
申请日:1978-02-23
IPC分类号: A61K39/12 , A61K39/165 , A61K39/20 , A61K39/16 , A61K39/34
CPC分类号: A61K39/165 , A61K39/12 , C12N7/00 , C12N2760/18434 , C12N2760/18451
摘要: A stabilized lyophlized or liquid live viral vaccine contains a live virus, partially hydrolyzed gelatin, a 6-carbon polyhydric alcohol, Medium 199 and acidic buffer.
摘要翻译: 稳定的冻干或液体活病毒疫苗含有活病毒,部分水解明胶,6-碳多元醇,培养基199和酸性缓冲液。
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公开(公告)号:US5888516A
公开(公告)日:1999-03-30
申请号:US969523
申请日:1997-10-22
申请人: Kathrin U. Jansen , James C. Cook, III , Hugh A. George , Kathryn J. Hofmann , Joseph G. Joyce , Ernest Dale Lehman , Henry Z. Markus , Mark Rosolowsky , Loren S. Schultz
发明人: Kathrin U. Jansen , James C. Cook, III , Hugh A. George , Kathryn J. Hofmann , Joseph G. Joyce , Ernest Dale Lehman , Henry Z. Markus , Mark Rosolowsky , Loren S. Schultz
IPC分类号: A61K38/00 , A61K39/00 , A61P31/00 , A61P37/04 , C07K14/025 , C12N15/81 , A61K39/12 , C12N7/04
CPC分类号: C07K14/005 , C12N15/81 , A61K38/00 , A61K39/00 , C12N2710/20022 , C12N2710/20023 , C12N2710/20034 , Y10S977/804 , Y10S977/915 , Y10S977/917 , Y10S977/918
摘要: Recombinant expression vectors encoding the L1 and L2 proteins of papillomavirus, methods of making and using the recombinant proteins and purified virus-like particles comprised of the recombinant proteins are provided.
摘要翻译: 提供了编码乳头瘤病毒的L1和L2蛋白的重组表达载体,制备和使用由重组蛋白组成的重组蛋白和纯化的病毒样颗粒的方法。
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公开(公告)号:US5024836A
公开(公告)日:1991-06-18
申请号:US423658
申请日:1989-10-19
IPC分类号: A61K39/245 , A61K39/295
CPC分类号: A61K39/245 , A61K39/12 , A61K2039/5254 , A61K2039/70 , A61K39/0015 , C12N2710/16734
摘要: The invention comprises a lyophilized live herpes virus vaccine that comprises from about 0.5% to about 8% moisture.
摘要翻译: 本发明包括冻干的活疱疹病毒疫苗,其包含约0.5%至约8%的水分。
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公开(公告)号:US4337242A
公开(公告)日:1982-06-29
申请号:US242195
申请日:1981-03-10
IPC分类号: A61K39/12 , A61K39/165 , A61K39/13 , A61K39/245
CPC分类号: A61K39/12 , A61K47/183 , A61K47/26 , A61K47/42 , A61K9/0019 , A61K2039/525 , C12N2760/18434
摘要: An improved stabilized liquid live viral vaccine contains a live virus, partially hydrolyzed gelatin, a monosaccharide or disaccharide, a cell culture medium, L-glutamic acid, L-arginine and sufficient physiologically acceptable acidic buffer to maintain the pH at from about 6.0 to about 6.5.
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