公开(公告)号：US20250019461A1

公开(公告)日：2025-01-16

申请号：US18886464

申请日：2024-09-16

Applicant: Hummingbird Bioscience Pte. Ltd.

Inventor： Jerome Douglas Boyd-Kirkup ,  Piers Ingram ,  Dipti Thakkar ,  Zhihao Wu ,  Konrad Paszkiewicz ,  Vicente Sancenon ,  Siyu Guan

IPC: C07K16/32 ,  A61K39/00 ,  A61P35/00 ,  C07K14/725 ,  C07K16/28 ,  C12N15/62 ,  C12N15/85

Abstract: HER3 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the HER3 antigen-binding molecules.

公开(公告)号：US20240279340A1

公开(公告)日：2024-08-22

申请号：US18570423

申请日：2022-06-13

Applicant: Hummingbird Bioscience Pte. Ltd.

Inventor： Jerome Douglas Boyd-Kirkup ,  Piers Ingram ,  Dipti Thakkar ,  Siyu Guan ,  Akila Sadasivam

IPC: C07K16/28 ,  A61K39/00 ,  A61P35/00

CPC classification number: C07K16/2827 ,  A61P35/00 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/73 ,  C07K2317/92 ,  C07K2317/94

Abstract: Cells expressing VISTA antigen-binding molecules are disclosed. Also disclosed are compositions comprising such cells, methods for producing VISTA antigen-binding molecules using such cells, and compositions comprising and methods using the VISTA antigen-binding molecules expressed by such cells.

公开(公告)号：US20240270871A1

公开(公告)日：2024-08-15

申请号：US18570460

申请日：2022-06-13

Applicant: Hummingbird Bioscience Pte. Ltd.

Inventor： Jerome Douglas Boyd-Kirkup ,  Piers Ingram ,  Dipti Thakkar ,  Siyu Guan ,  Akila Sadasivam

IPC: C07K16/32 ,  G01N33/574

CPC classification number: C07K16/32 ,  G01N33/5748 ,  C07K2317/14 ,  C07K2317/73 ,  C07K2317/732 ,  C07K2317/76 ,  C07K2317/92 ,  G01N2333/71

Abstract: Cells expressing HER3 antigen-binding molecules are disclosed. Also disclosed are compositions comprising such cells, methods for producing HER3 antigen-binding molecules using such cells, and compositions comprising and methods using the HER3 antigen-binding molecules expressed by such cells.

公开(公告)号：US11873346B2

公开(公告)日：2024-01-16

申请号：US16823280

申请日：2020-03-18

Applicant: Hummingbird Bioscience Pte. Ltd.

Inventor： Jerome Douglas Boyd-Kirkup ,  Piers Ingram ,  Dipti Thakkar ,  Zhihao Wu ,  Konrad Paszkiewicz ,  Vicente Sancenon ,  Siyu Guan

IPC: A61K39/00 ,  C07K16/46

CPC classification number: C07K16/464 ,  C07K16/468 ,  C07K2317/522 ,  C07K2317/524 ,  C07K2317/526 ,  C07K2317/565 ,  C07K2317/567 ,  C07K2317/72

Abstract: VISTA antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the VISTA antigen-binding molecules.