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公开(公告)号:US20190300610A1
公开(公告)日:2019-10-03
申请号:US16180949
申请日:2018-11-05
Inventor: Jerome Douglas Boyd-Kirkup , Piers Ingram , Dipti Thakkar , Zhihao Wu , Konrad Paszkiewicz , Vicente Sancenon , Siyu Guan
Abstract: V-type immunoglobulin domain-containing suppressor of T-cell activation (VISTA) antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the VISTA antigen-binding molecules.
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公开(公告)号:US20240158538A1
公开(公告)日:2024-05-16
申请号:US18518192
申请日:2023-11-22
Applicant: Hummingbird Bioscience Pte. Ltd.
Inventor: Jerome Boyd-Kirkup , Piers Ingram , Dipti Thakkar , Zhihao Wu , Konrad Paszkiewicz , Vicente Sancenon , Siyu Guan
IPC: C07K16/46
CPC classification number: C07K16/464 , C07K16/468 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/565 , C07K2317/567 , C07K2317/72
Abstract: VISTA antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the VISTA antigen-binding molecules.
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公开(公告)号:US20190300624A1
公开(公告)日:2019-10-03
申请号:US16170370
申请日:2018-10-25
Applicant: Hummingbird Bioscience Pte. Ltd.
Inventor: Jerome Douglas Boyd-Kirkup , Siyu Guan , Piers Ingram , Konrad Paszkiewicz , Vicente Sancenon , Dipti Thakkar , Zhihao Wu
IPC: C07K16/32 , A61P35/00 , C07K14/725 , C12N15/62 , C12N15/85
Abstract: HER3 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the HER3 antigen-binding molecules.
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公开(公告)号:US20240092937A1
公开(公告)日:2024-03-21
申请号:US18458997
申请日:2023-08-30
Applicant: Hummingbird Bioscience Pte. Ltd.
Inventor: Jerome Douglas Boyd-Kirkup , Piers Ingram , Dipti Thakkar , Zhihao Wu , Konrad Paszkiewicz , Vicente Sancenon , Siyu Guan
CPC classification number: C07K16/32 , A61P35/00 , C07K14/7051 , C07K16/28 , C12N15/62 , C12N15/85 , A61K2039/505
Abstract: HER3 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the HER3 antigen-binding molecules.
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公开(公告)号:US20250122303A1
公开(公告)日:2025-04-17
申请号:US18688576
申请日:2022-09-02
Inventor: Nigel Westwood , Harriet Walters , Gavin Halbert , Jennifer L. Craigen , Siyu Guan , Jerome Boyd-Kirkup , Piers Ingram , Dipti Thakkar
IPC: C07K16/32 , A61K31/4166 , A61K39/00 , A61P35/00
Abstract: The present disclosure provides antigen-binding molecules that bind to HER3 for the treatment or prevention of cancers, compositions comprising said molecules, and therapeutic and prophylactic methods using said molecules.
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公开(公告)号:US11780933B2
公开(公告)日:2023-10-10
申请号:US16805620
申请日:2020-02-28
Applicant: Hummingbird Bioscience Pte. Ltd.
Inventor: Jerome Douglas Boyd-Kirkup , Piers Ingram , Dipti Thakkar , Zhihao Wu , Konrad Paszkiewicz , Vicente Sancenon , Siyu Guan
IPC: A61K39/395 , C07K16/32 , C07K16/28 , A61P35/00 , C07K14/725 , C12N15/62 , C12N15/85 , A61K39/00
CPC classification number: C07K16/32 , A61P35/00 , C07K14/7051 , C07K16/28 , C12N15/62 , C12N15/85 , A61K2039/505 , C07K2317/24 , C07K2317/33 , C07K2317/522 , C07K2317/524 , C07K2317/526 , C07K2317/565 , C07K2317/622 , C07K2317/72 , C07K2317/76 , C07K2317/77 , C07K2317/92
Abstract: HER3 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the HER3 antigen-binding molecules.
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公开(公告)号:US11685789B2
公开(公告)日:2023-06-27
申请号:US17847020
申请日:2022-06-22
Applicant: Hummingbird Bioscience Pte. Ltd.
Inventor: Jerome Boyd-Kirkup , Dipti Thakkar , Piers Ingram , Zhihao Wu , Konrad Paszkiewicz , Peter Brauer , Siyu Guan
CPC classification number: C07K16/2896 , A61K39/39558 , A61P35/00 , C07H21/00 , C07K16/2803 , C12N15/09 , C12N15/62 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/55 , C07K2317/565 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C12N15/11
Abstract: CD47 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the CD47 antigen-binding molecules.
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公开(公告)号:US20250019461A1
公开(公告)日:2025-01-16
申请号:US18886464
申请日:2024-09-16
Applicant: Hummingbird Bioscience Pte. Ltd.
Inventor: Jerome Douglas Boyd-Kirkup , Piers Ingram , Dipti Thakkar , Zhihao Wu , Konrad Paszkiewicz , Vicente Sancenon , Siyu Guan
Abstract: HER3 antigen-binding molecules are disclosed. Also disclosed are nucleic acids and expression vectors encoding, compositions comprising, and methods using, the HER3 antigen-binding molecules.
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公开(公告)号:US20240279340A1
公开(公告)日:2024-08-22
申请号:US18570423
申请日:2022-06-13
Applicant: Hummingbird Bioscience Pte. Ltd.
Inventor: Jerome Douglas Boyd-Kirkup , Piers Ingram , Dipti Thakkar , Siyu Guan , Akila Sadasivam
CPC classification number: C07K16/2827 , A61P35/00 , A61K2039/505 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , C07K2317/94
Abstract: Cells expressing VISTA antigen-binding molecules are disclosed. Also disclosed are compositions comprising such cells, methods for producing VISTA antigen-binding molecules using such cells, and compositions comprising and methods using the VISTA antigen-binding molecules expressed by such cells.
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公开(公告)号:US20240270871A1
公开(公告)日:2024-08-15
申请号:US18570460
申请日:2022-06-13
Applicant: Hummingbird Bioscience Pte. Ltd.
Inventor: Jerome Douglas Boyd-Kirkup , Piers Ingram , Dipti Thakkar , Siyu Guan , Akila Sadasivam
IPC: C07K16/32 , G01N33/574
CPC classification number: C07K16/32 , G01N33/5748 , C07K2317/14 , C07K2317/73 , C07K2317/732 , C07K2317/76 , C07K2317/92 , G01N2333/71
Abstract: Cells expressing HER3 antigen-binding molecules are disclosed. Also disclosed are compositions comprising such cells, methods for producing HER3 antigen-binding molecules using such cells, and compositions comprising and methods using the HER3 antigen-binding molecules expressed by such cells.
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