公开(公告)号：US20100160349A1

公开(公告)日：2010-06-24

申请号：US11813973

申请日：2006-01-13

申请人： Christopher John Love ,  Ludwig Paul Cooymans ,  Nele Vandermaesen

发明人： Christopher John Love ,  Ludwig Paul Cooymans ,  Nele Vandermaesen

IPC分类号： A61K31/519 ,  C07D487/04 ,  A61P7/12 ,  A61P25/28 ,  A61P25/16 ,  A61P25/18 ,  A61P25/24 ,  A61P37/06 ,  A61P17/00 ,  A61P3/10 ,  A61P35/00

CPC分类号： C07D487/04

摘要： This invention concerns a compound of formula a N-oxide, a pharmaceutically acceptable addition salt, a quaternary amine and a stereochemically isomeric form thereof, wherein ring A represents phenyl, pyridyl, pyrimidinyl, pyridazinyl or pyrazinyl; R1 represents hydrogen; aryl; formyl; C1-6alkylcarbonyl; C1-6alkyl; C1-6alkyloxycarbonyl; C1-6alkyl substituted with formyl, C1-6alkylcarbonyl, C1-6alkyloxycarbonyl or C1-6alkylcarbonyloxy; X represents a direct bond; —(CH2)n3— or —(CH2)n4—X1a—X1b—; R2 represents an optionally substituted cyclic system; provided that N,3-diphenyl-3H-1,2,3-triazolo[4,5-d]pyrimidin-5-amine is not included; their use, pharmaceutical compositions comprising them and processes for their preparation.

摘要翻译： 本发明涉及下式的化合物：N-氧化物，药学上可接受的加成盐，季胺及其立体化学异构形式，其中环A表示苯基，吡啶基，嘧啶基，哒嗪基或吡嗪基; R1表示氢; 芳基; 甲酰基 C 1-6烷基羰基; C 1-6烷基; C 1-6烷氧基羰基; 被甲酰基，C 1-6烷基羰基，C 1-6烷氧基羰基或C 1-6烷基羰氧基取代的C 1-6烷基; X表示直接键; - （CH 2）n3-或 - （CH 2）n4-X1a-X1b-; R2表示任选取代的环状体系; 条件是不包括N，3-二苯基-3H-1,2,3-三唑并[4,5-d]嘧啶-5-胺; 其用途，包含它们的药物组合物及其制备方法。

公开(公告)号：US20090295468A1

公开(公告)日：2009-12-03

申请号：US12154913

申请日：2008-05-28

申请人： John Love

发明人： John Love

IPC分类号： G05F1/00

CPC分类号： H02J9/005 ,  Y10T307/297 ,  Y10T307/391 ,  Y10T307/406

摘要： A system is disclosed for reducing power drain of a component when the component is in a powered down state. The system comprises a power input configured to receive power, a power output to the component, monitor logic configured to monitor a level of power moving between the input and output, and control logic configured to control power transfer between the input and output. The control logic may be in communication with the monitor logic and configured to selectively restrict power flow between the input and output when the monitor logic senses that power flow between the input and output falls below a threshold level. A method comprises checking a power level between the input and output, and if the power level exceeds a threshold, then permitting substantially unrestricted power flow. If the power level is less than the threshold, then restricting the power level between the input and output.

摘要翻译： 公开了一种用于当组件处于掉电状态时减少组件的功率消耗的系统。 该系统包括被配置为接收功率的功率输入，到组件的功率输出，被配置为监视在输入和输出之间移动的功率水平的监视逻辑，以及被配置为控制输入和输出之间的功率传输的控制逻辑。 控制逻辑可以与监视器逻辑通信，并且被配置为当监视器逻辑检测到输入和输出之间的功率流低于阈值水平时选择性地限制输入和输出之间的功率流。 一种方法包括检查输入和输出之间的功率电平，并且如果功率电平超过阈值，则允许基本上不受限制的功率流。 如果功率电平小于阈值，则限制输入和输出之间的功率电平。

公开(公告)号：US07560458B2

公开(公告)日：2009-07-14

申请号：US10564844

申请日：2004-07-12

申请人： Eddy Jean Edgard Freyne ,  Christopher John Love ,  Ludwig Paul Cooymans ,  Nele Vandermaesen ,  Peter Jacobus Johannes Antonius Buijnsters ,  Marc Willems ,  Werner Constant Johan Embrechts

发明人： Eddy Jean Edgard Freyne ,  Christopher John Love ,  Ludwig Paul Cooymans ,  Nele Vandermaesen ,  Peter Jacobus Johannes Antonius Buijnsters ,  Marc Willems ,  Werner Constant Johan Embrechts

IPC分类号： A61K31/535 ,  A61K31/501 ,  A61K31/519 ,  A01N43/90 ,  C07D413/00 ,  C07D401/00 ,  C07D403/00 ,  C07D405/00 ,  C07D409/00 ,  C07D239/00 ,  C07D471/00 ,  C07D487/00 ,  C07D491/00

CPC分类号： C07D487/04

摘要： This invention concerns compounds of formula N-oxides, pharmaceutically acceptable addition salts, quaternary amines and stereochemically isomeric forms thereof, their use, pharmaceutical compositions comprising them, and processes for their preparation.

摘要翻译： 本发明涉及式N-氧化物的化合物，药学上可接受的加成盐，季胺及其立体化学异构形式，其用途，包含它们的药物组合物及其制备方法。

公开(公告)号：US20080308429A1

公开(公告)日：2008-12-18

申请号：US11764263

申请日：2007-06-18

申请人： BRUCE JOHN LOVE

发明人： BRUCE JOHN LOVE

IPC分类号： C25C1/08 ,  C25C7/02 ,  H01M6/04

CPC分类号： C25C1/08 ,  C25C7/02 ,  H01M4/0438 ,  H01M4/045 ,  H01M2004/028

摘要： An acidic aqueous electrolyte solution for production of a nickel cathode is provided which includes nickel ions, and 2,5-dimethyl-3-hexyne-2,5-diol. The 2,5-dimethyl-3-hexyne-2,5-diol may be present in the acidic aqueous electrolyte solution in an amount ranging from about 5 ppm to about 300 ppm. Also provided is a process for electrowinning or electrorefining a nickel cathode which includes providing an acidic aqueous electrolyte solution including nickel ions, and 2,5-dimethyl-3-hexyne-2,5-diol; and electrolytically depositing nickel to form a nickel cathode. Addition of 2,5-dimethyl-3-hexyne-2,5-diol results in a reduction of striations and other defects which may occur on the surface of cathodes made by electrowinning or electrorefining.

摘要翻译： 提供了一种用于生产镍阴极的酸性电解质水溶液，其包括镍离子和2,5-二甲基-3-己炔-2,5-二醇。 2,5-二甲基-3-己炔-2,5-二醇可以以约5ppm至约300ppm的量存在于酸性电解质水溶液中。 还提供了一种镍电解电解冶炼或电解精炼方法，其包括提供包含镍离子的酸性电解质溶液和2,5-二甲基-3-己炔-2,5-二醇; 并电解沉积镍以形成镍阴极。 加入2,5-二甲基-3-己炔-2,5-二醇可以减少由电解冶金或电解精炼制成的阴极表面上可能发生的条纹和其他缺陷。

公开(公告)号：US07449465B2

公开(公告)日：2008-11-11

申请号：US10565065

申请日：2004-07-12

申请人： Eddy Jean Edgard Freyne ,  Christopher John Love ,  Ludwig Paul Cooymans ,  Nele Vandermaesen ,  Peter Jacobus Johannes Antonius Buijnsters ,  Marc Willems ,  Werner Constant Johan Embrechts

发明人： Eddy Jean Edgard Freyne ,  Christopher John Love ,  Ludwig Paul Cooymans ,  Nele Vandermaesen ,  Peter Jacobus Johannes Antonius Buijnsters ,  Marc Willems ,  Werner Constant Johan Embrechts

IPC分类号： A61K31/501 ,  A61K31/4965 ,  A61K31/519 ,  A01N43/90 ,  C07D401/00 ,  C07D403/00 ,  C07D405/00 ,  C07D409/00 ,  C07D239/00 ,  C07D471/00 ,  C07D487/00 ,  C07D491/00

CPC分类号： C07D487/04

摘要： This invention concerns compounds of formula N-oxides, pharmaceutically acceptable addition salts, quaternary amines and stereochemically isomeric forms thereof, their use, pharmaceutical compositions comprising them, and processes for their preparation.

摘要翻译： 本发明涉及式N-氧化物的化合物，药学上可接受的加成盐，季胺及其立体化学异构形式，其用途，包含它们的药物组合物及其制备方法。

公开(公告)号：US20080121216A1

公开(公告)日：2008-05-29

申请号：US11604579

申请日：2006-11-27

申请人： Scott F. Shafer ,  Timur Trubnikov ,  William John Love ,  Heather Rebholz ,  Jianhua Zhang

发明人： Scott F. Shafer ,  Timur Trubnikov ,  William John Love ,  Heather Rebholz ,  Jianhua Zhang

IPC分类号： F02M37/06

CPC分类号： F04B1/0413 ,  F02M59/06 ,  F02M59/366 ,  F02M63/0295 ,  F02M2200/03 ,  F04B1/02 ,  F04B1/0538 ,  F04B9/042 ,  F04B49/24 ,  F04B2201/1202 ,  F04B2201/1207

摘要： A high volume high pressure common rail pump for a fuel system includes pairs of pump head assemblies in phase with each other but oriented in opposition to one another about a rotating cam shaft. Pump pistons in the pump head assemblies simultaneously undergo pumping strokes via a shared two lobe cam of the rotating cam shaft. The pump may include two pairs of pump head assemblies, and each head assembly may include two pump pistons. The cam shaft includes two cams sufficiently out of phase with one another that the cam shaft always has a positive torque even when the cam lobes are symmetrical. In addition, because the pumping is done simultaneously on opposite sides of the cam shaft, the forces on the cam shaft are balanced and its support bearings experience less wear and tear.

摘要翻译： 用于燃料系统的高容量高压共轨泵包括相互相位但相对于旋转的凸轮轴彼此相对定向的成对的泵头组件。 泵头组件中的泵活塞同时通过旋转凸轮轴的共享的两个凸角凸轮进行泵送冲程。 泵可以包括两对泵头组件，并且每个头组件可以包括两个泵活塞。 凸轮轴包括彼此完全不相位的两个凸轮，即使当凸轮凸角对称时，凸轮轴总是具有正转矩。 另外，由于在凸轮轴的相对侧同时进行泵送，所以凸轮轴上的力是平衡的，并且其支撑轴承经历较少的磨损。

公开(公告)号：US07362563B2

公开(公告)日：2008-04-22

申请号：US11284480

申请日：2005-11-22

申请人： John Love

发明人： John Love

IPC分类号： H05K7/12

CPC分类号： G06F1/1616 ,  G06F2200/1632

摘要： A system that includes an electronic device (such as a portable computer), a writing instrument, and a receptacle located on the device for removably receiving the writing instrument. The receptacle includes an opening on the device and a channel in communication with the opening and extending inwardly with respect to the device. The system further includes an adapter structure configured to change an effective width of the channel between at least two widths to thereby hold writing instruments of different widths in the receptacle.

摘要翻译： 一种包括电子设备（例如便携式计算机），书写工具和位于设备上用于可移除地接收书写工具的插座的系统。 插座包括设备上的开口和与开口连通且相对于装置向内延伸的通道。 该系统还包括适配器结构，其配置成在至少两个宽度之间改变通道的有效宽度，从而将不同宽度的书写工具保持在容器中。

公开(公告)号：US20070185659A1

公开(公告)日：2007-08-09

申请号：US11350456

申请日：2006-02-09

申请人： John Love

发明人： John Love

IPC分类号： G06F19/00

CPC分类号： G01N30/88 ,  G01N2030/8804

摘要： An apparatus for determining whether a mechanical component in a chemical composition analyzer is defective, the apparatus including a mechanical component, a transducer coupled to the mechanical component, the transducer configured to measure a mechanical component property, and a processor in communication with the transducer, the processor configured to determine whether the mechanical component is defective using the mechanical component property. In an embodiment, the processor is configured to compare the mechanical component property to a baseline to determine whether the mechanical component property is within a predetermined range of the baseline, and responsive to the determination that the mechanical component property is not within the predetermined range of the baseline, indicate that the mechanical component is defective. In other embodiments, the mechanical component is a valve and the apparatus is incorporated into a chemical composition analyzer. Also disclosed is a method for determining whether a mechanical component in a chemical composition analyzer is defective.

摘要翻译： 一种用于确定化学成分分析仪中的机械部件是否有缺陷的装置，所述装置包括机械部件，耦合到所述机械部件的换能器，被配置为测量机械部件特性的所述换能器以及与所述换能器通信的处理器， 所述处理器被配置为使用所述机械部件特性来确定所述机械部件是否有缺陷。 在一个实施例中，处理器被配置为将机械部件属性与基准值进行比较，以确定机械部件属性是否在基准线的预定范围内，并且响应于机械部件特性不在预定范围内的确定 基线表示机械部件有缺陷。 在其它实施例中，机械部件是阀，并且该装置被结合到化学成分分析器中。 还公开了一种用于确定化学成分分析仪中的机械组分是否有缺陷的方法。

公开(公告)号：US08620750B2

公开(公告)日：2013-12-31

申请号：US13277923

申请日：2011-10-20

申请人： Thomas DePasquale ,  John Love ,  Michael Lore ,  Michael Fredericks ,  Andrew Csontos

发明人： Thomas DePasquale ,  John Love ,  Michael Lore ,  Michael Fredericks ,  Andrew Csontos

IPC分类号： G06Q30/00

CPC分类号： G06Q30/0261 ,  G06Q10/02 ,  G06Q30/0205 ,  G06Q30/0271 ,  H04W4/025 ,  H04W4/06 ,  H04W4/21

摘要： A computer-implemented method of targeting electronic messages to travelers, comprising performing processing associated with: utilizing geographic information comprising itinerary information, to determine where the travelers are currently and/or are projected to be during a given time period; creating a list of travelers which categorizes the geographic information and/or traveler information about the travelers on the list; electronically notifying a merchant with information related to the list and the current geographic information and/or current traveler information of the travelers on the list; receiving an electronic request from the merchant to transmit an electronic targeted message to some or all of the travelers on the list; and transmitting the electronic targeted message to some or all of the travelers on the list.

摘要翻译： 一种针对电子消息到旅行者的计算机实现的方法，包括执行与以下相关联的处理的处理：利用包括行程信息的地理信息来确定旅行者当前和/或预定在给定时间段内的位置; 创建一份旅客名单，对列表上的旅客的地理信息和/或旅行者信息进行分类; 以电子方式向商家通报与列表相关的信息，以及当前地理信息和/或列表上的旅行者的当前旅行者信息; 接收来自商家的电子请求，以将电子目标消息发送到列表上的某些或全部旅行者; 并将电子目标消息发送到列表上的一些或全部旅行者。

公开(公告)号：US20120101858A1

公开(公告)日：2012-04-26

申请号：US13277916

申请日：2011-10-20

申请人： Thomas Depasquale ,  John Love ,  Michael Lore ,  Michael Fredericks ,  Andrew Csontos

发明人： Thomas Depasquale ,  John Love ,  Michael Lore ,  Michael Fredericks ,  Andrew Csontos

IPC分类号： G06Q10/02

CPC分类号： G06Q30/0261 ,  G06Q10/02 ,  G06Q30/0205 ,  G06Q30/0271 ,  H04W4/025 ,  H04W4/06 ,  H04W4/21

摘要： A computer-implemented system and method for targeting messages to a traveler, comprising processing information associated with: receiving a request from a device of the traveler for itinerary information; utilizing geographic information, comprising itinerary information, to determine where the traveler is currently and/or is projected to be during a given time period; categorizing the geographic information and traveler information about the traveler from a database of travel and expense activity into a category; matching the category for the geographical information and/or traveler information about the traveler against a category for available targeted messages to determine if there are any matches; and transmitting targeted messages that have a category that matches a category for the geographical information and/or traveler information to the device of the traveler; wherein traveler information from the database of travel and expense activity is utilized to help determine what products and/or services travelers purchase when they travel.

摘要翻译： 一种用于将消息定位到旅行者的计算机实现的系统和方法，包括处理与之相关联的信息：从所述旅行者的设备接收针对行程信息的请求; 利用地理信息，包括行程信息，以确定旅行者当前和/或预计在给定时间段内的位置; 将旅行者的地理信息和旅行者信息从旅行和费用活动数据库分类为一类; 将关于旅行者的地理信息和/或旅行者信息的类别与可用的目标消息的类别进行匹配，以确定是否存在任何匹配; 以及将具有与用于地理信息和/或旅行者信息的类别匹配的类别的目标消息传送到旅行者的设备; 来自旅行和费用活动数据库的旅行者信息用于帮助确定旅行者在旅行时购买什么产品和/或服务。