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    Hybrid bioreactor for cell culture
    11.
    发明授权
    Hybrid bioreactor for cell culture 失效
    用于细胞培养的混合生物反应器

    公开(公告)号：US07510866B2

    公开(公告)日：2009-03-31

    申请号：US10535141

    申请日：2003-10-29

    Applicant: Kuiwon Choi ,  Tae Soo Bae ,  Jung Kyu Kim ,  Chang Yang Lee

    Inventor： Kuiwon Choi ,  Tae Soo Bae ,  Jung Kyu Kim ,  Chang Yang Lee

    IPC: C12M1/00

    CPC classification number: C12M27/10 ,  C12M23/08 ,  C12M23/46 ,  Y10S623/911 ,  Y10S623/917 ,  Y10S623/924

    Abstract: A hybrid bioreactor for cell culture is disclosed. To simultaneously apply compressive strain for cell differentiation and shear strain for cell proliferation to cells, the hybrid bioreactor includes a plurality of reactor tube assemblies (100), a compressive strain motor (5), a shear strain motor (25), a lower anchor mount (20) having a plurality of toothed anchors (70) to respectively anchor the lower ends of the reactor tube assemblies (100) to the lower anchor mount (20), a ball screw (90) operated in conjunction with the compressive strain motor (5), an upper anchor mount (60) which engages with the ball screw (90) to vertically move upward and downward and having a plurality of compressive strain anchors (80) to anchor the upper ends of the reactor tube assemblies (100) to the upper anchor mount (60), a power transmission unit to transmit the rotating force of the shear strain motor (25) to the toothed anchors (70).

    Abstract translation: 公开了用于细胞培养的杂交生物反应器。 为了同时将细胞分化的压缩应变和细胞增殖的剪切应变施加到细胞，混合生物反应器包括多个反应器管组件（100），压缩应变马达（5），剪切应变马达（25），下锚 安装件（20）具有多个齿形锚固件（70），以将反应器管组件（100）的下端分别锚固到下部锚固件安装件（20）;滚珠丝杠（90），与压缩应变马达 （5），与所述滚珠丝杠（90）接合以垂直向上和向下移动并具有多个压缩应变锚（80）以锚固所述反应器管组件（100）的上端的上锚固支架（60） 到上锚固装置（60），用于将剪切应变马达（25）的旋转力传递到齿形锚杆（70）的动力传递单元。

    Hybrid bioreactor for cell culture
    12.
    发明申请
    Hybrid bioreactor for cell culture 失效
    用于细胞培养的混合生物反应器

    公开(公告)号：US20060068492A1

    公开(公告)日：2006-03-30

    申请号：US10535141

    申请日：2003-10-29

    Applicant: Kuiwon Choi ,  Jung Kim ,  Tae Bae ,  Chang Lee

    Inventor： Kuiwon Choi ,  Jung Kim ,  Tae Bae ,  Chang Lee

    IPC: C12M3/00

    CPC classification number: C12M27/10 ,  C12M23/08 ,  C12M23/46 ,  Y10S623/911 ,  Y10S623/917 ,  Y10S623/924

    Abstract: A hybrid bioreactor for cell culture is disclosed. To simultaneously apply compressive strain for cell differentiation and shear strain for cell proliferation to cells, the hybrid bioreactor includes a plurality of reactor tube assemblies (100), a compressive strain motor (5), a shear strain motor (25), a lower anchor mount (20) having a plurality of toothed anchors (70) to respectively anchor the lower ends of the reactor tube assemblies (100) to the lower anchor mount (20), a ball screw (90) operated in conjunction with the compressive strain motor (5), an upper anchor mount (60) which engages with the ball screw (90) to vertically move upward and downward and having a plurality of compressive strain anchors (80) to anchor the upper ends of the reactor tube assemblies (100) to the upper anchor mount (60), a power transmission unit to transmit the rotating force of the shear strain motor (25) to the toothed anchors (70).

    Abstract translation: 公开了用于细胞培养的杂交生物反应器。 为了同时将细胞分化的压缩应变和细胞增殖的剪切应变施加到细胞，混合生物反应器包括多个反应器管组件（100），压缩应变马达（5），剪切应变马达（25），下锚 安装件（20）具有多个齿形锚固件（70），以将反应器管组件（100）的下端分别锚固到下部锚固件安装件（20）;滚珠丝杠（90），与压缩应变马达 （5），与所述滚珠丝杠（90）接合以垂直向上和向下移动并具有多个压缩应变锚（80）以锚固所述反应器管组件（100）的上端的上锚固支架（60） 到上锚固装置（60），用于将剪切应变马达（25）的旋转力传递到齿形锚杆（70）的动力传递单元。

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