HEART VALVE PROSTHESIS AND METHODS OF MANUFACTURE AND USE

    公开(公告)号:US20210298895A1

    公开(公告)日:2021-09-30

    申请号:US17221895

    申请日:2021-04-05

    Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.

    INTEGRATED LOADING AND STORAGE SYSTEM FOR IMPLANTABLE MEDICAL DEVICES

    公开(公告)号:US20210153998A1

    公开(公告)日:2021-05-27

    申请号:US16697965

    申请日:2019-11-27

    Abstract: A loading device includes a locking collar assembly including a proximal end, a distal end, and a loading channel formed between the proximal end and the distal end. The device also includes a loading funnel coupled to the distal end of the locking collar assembly at a proximal end of the loading funnel. The loading funnel is configured to store a collapsible medical device in a partially collapsed state within a tapered interior volume of the loading funnel. The tapered interior volume decreases in volume from a distal end of the loading funnel to the proximal end of the loading funnel.

    VALVE DELIVERY SYSTEM INCLUDING FORESHORTENING COMPENSATOR FOR IMPROVED POSITIONING ACCURACY

    公开(公告)号:US20210106421A1

    公开(公告)日:2021-04-15

    申请号:US16596937

    申请日:2019-10-09

    Abstract: A system including a self-expanding prosthesis configured to foreshorten during deployment thereof and a delivery device configured to percutaneously deliver the self-expanding prosthesis. The delivery device includes a handle having an actuator thereon, an outer sheath including a proximal end coupled to the handle and a pusher shaft slidingly disposed within the outer sheath. The pusher shaft has a proximal end coupled to the handle and a distal end configured to releasably couple to the self-expanding prosthesis such that the self-expanding prosthesis axially moves therewith. The inner shaft has a distal portion of the inner shaft that is configured to receive a self-expanding prosthesis thereon. The outer sheath and the pusher shaft are configured to simultaneously move in opposing axial directions via actuation of the actuator on the handle to compensate for the foreshortening of the self-expanding prosthesis during deployment.

    DISTAL TIP ASSEMBLY FOR A HEART VALVE DELIVERY CATHETER

    公开(公告)号:US20200222184A1

    公开(公告)日:2020-07-16

    申请号:US16831905

    申请日:2020-03-27

    Inventor: John GALLAGHER

    Abstract: A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.

    HEART VALVE PROSTHESIS AND METHODS OF MANUFACTURE AND USE

    公开(公告)号:US20200046493A1

    公开(公告)日:2020-02-13

    申请号:US16600854

    申请日:2019-10-14

    Abstract: A heart valve prosthesis is provided having a self-expanding multi-level frame that supports a valve body comprising a skirt and plurality of coapting leaflets. The frame transitions between a contracted delivery configuration that enables percutaneous transluminal delivery, and an expanded deployed configuration having an asymmetric hourglass shape. The valve body skirt and leaflets are constructed so that the center of coaptation may be selected to reduce horizontal forces applied to the commissures of the valve, and to efficiently distribute and transmit forces along the leaflets and to the frame. Alternatively, the valve body may be used as a surgically implantable replacement valve prosthesis.

    Anti-paravalvular leakage component for a transcatheter valve prosthesis

    公开(公告)号:US10413401B2

    公开(公告)日:2019-09-17

    申请号:US13757380

    申请日:2013-02-01

    Abstract: A transcatheter valve prosthesis includes an expandable tubular stent, a prosthetic valve within the stent, and an anti-paravalvular leakage component coupled to and encircling the tubular stent. The anti-paravalvular leakage component includes a radially-compressible annular scaffold, which is a sinusoidal patterned ring of self-expanding material, and an impermeable membrane extending over the annular scaffold. The anti-paravalvular leakage component has an expanded configuration in which at least segments of the annular scaffold curve radially away from the tubular stent. Alternatively, the anti-paravalvular leakage component includes a plurality of self-expanding segments and an annular sealing element coupled to inner surfaces of the segments. The anti-paravalvular leakage component has an expanded configuration in which the segments curve radially away from the tubular stent and the annular sealing element is positioned between an outer surface of the tubular stent and inner surfaces of the segments.

    Delivery system for deployment of medical devices

    公开(公告)号:US10321997B2

    公开(公告)日:2019-06-18

    申请号:US15361617

    申请日:2016-11-28

    Abstract: A catheter that comprises a sheath that is connected at opposing ends to concentric tubes that move relative to each other in a manner that alternatively covers and exposes a medical device loaded onto the catheter. A portion of the sheath is arranged so as to invert upon itself so that axial movement of one tube relative to the other simultaneously moves the inversion point over or away from the device, alternatively covering or exposing the device.

    DISTAL TIP ASSEMBLY FOR A HEART VALVE DELIVERY CATHETER

    公开(公告)号:US20170100247A1

    公开(公告)日:2017-04-13

    申请号:US15387112

    申请日:2016-12-21

    Inventor: John Gallagher

    Abstract: A catheter assembly according to the present invention includes a handle assembly, an introducer sheath, and a distal tip assembly. The distal tip assembly can include first and second retaining sleeves and a slotted tip with a non-traumatic tip guard positioned at the proximal end of the slotted tip. The handle assembly can include a fixed main handle and two or more rotating handles that allow a user to control the distal tip assembly of the catheter. Each control knob on the handle assembly controls a portion of the components on the distal tip of the catheter by allowing for precise manipulation of various delivery shafts. Each delivery shaft extends from the handle assembly to respective positions towards the distal end of the catheter.

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