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11.发明授权Oral care compositions comprising tropolone compounds and essential oils and methods of using the same 失效包含托普罗酮化合物和精油的口腔护理组合物及其使用方法公开(公告)号：US06689342B1
公开(公告)日：2004-02-10
申请号：US10207726
申请日：2002-07-29
IPC分类号： A61K716
摘要： The present invention relates to oral care compositions suitable for preventing or treating diseases or conditions of the oral cavity in warm-blooded animals including humans, comprising an oral care effective amount of at least one tropolone compound in combination with at least one essential oil, and a pharmaceutically acceptable oral carrier. This invention further relates to a method for preventing or treating diseases or conditions of the oral cavity in warm-blooded animals including humans, by applying an oral care effective amount of the oral care composition to the oral cavity.
摘要翻译： 本发明涉及适用于预防或治疗包括人类在内的温血动物的口腔疾病或病症的口腔护理组合物，其包含口服护理有效量的至少一种托乐芬化合物与至少一种精油的组合，和 药学上可接受的口服载体。 本发明还涉及通过将口腔护理有效量的口腔护理组合物应用于口腔来预防或治疗包括人在内的温血动物的口腔疾病或病症的方法。
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公开(公告)号：US5891422A
公开(公告)日：1999-04-06
申请号：US722450
申请日：1996-10-10
申请人： Pauline Pan , Edward Carlin , R. Michael Buch , Frank Volpe , Alain Martin
发明人： Pauline Pan , Edward Carlin , R. Michael Buch , Frank Volpe , Alain Martin
摘要： An antimicrobial composition containing an alcohol having 3 to 6 carbon atoms which effectively increases antimicrobial activity and particularly a mouthwash composition that is useful in the prevention and reduction of bad breath, plaque and related gum diseases having an antimicrobially effective amount of one or more active essential oils; from about 0.01% to about 30.0% v/v of an alcohol having 3 to 6 carbon atoms; optionally, ethanol; at least one surfactant; and water. The actives not only provide enhanced efficacy but are completely solubilized, thus providing an aesthetically appealing product.
摘要翻译： 一种抗微生物组合物，其含有具有3至6个碳原子的醇，其有效地增加了抗微生物活性，特别是漱口水组合物，其可用于预防和减少口臭，斑块和相关的牙龈疾病，其具有抗微生物有效量的一种或多种活性成分 油 约0.01％至约30.0％v / v的具有3至6个碳原子的醇; 任选地，乙醇; 至少一种表面活性剂; 和水。 活性物质不仅提供增强的功效，而且完全溶解，从而提供美观的产品。
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