公开(公告)号：US08135468B2

公开(公告)日：2012-03-13

申请号：US12853157

申请日：2010-08-09

申请人： Dan E. Gutfinger ,  Fujian Qu ,  Alex Soriano ,  Ryan Rooke ,  Yelena Nabutovsky ,  Riddhi Shah

发明人： Dan E. Gutfinger ,  Fujian Qu ,  Alex Soriano ,  Ryan Rooke ,  Yelena Nabutovsky ,  Riddhi Shah

IPC分类号： A61N1/00

CPC分类号： A61N1/36585 ,  A61B5/0215 ,  A61B5/02158 ,  A61N1/36521 ,  A61N1/36564 ,  A61N1/36578 ,  A61N1/37235 ,  A61N1/37258 ,  A61N1/3962

摘要： Various techniques are provided for use with an implantable medical device for estimating cardiac pressure within a patient based on admittance (or related electrical values such as impedance or conductance) that takes into account the presence of acute MR within the patient. Briefly, the device detects an indication of acute MR, if occurring within the patient. The device also applies electrical fields to tissues of the patient and measures electrical parameters influenced by the electrical field, such as admittance, impedance or conductance. The device then estimates cardiac pressure within the patient based on the measured electrical parameter and the indication of acute MR. In one example, different linear correlation functions are used to convert admittance values to left atrial pressure (LAP) values depending upon the presence or absence of acute MR within the patient.

摘要翻译： 提供了与植入式医疗装置一起使用的各种技术，其基于考虑到患者内急性MR的存在的导纳（或相关的电气值，例如阻抗或电导）来估计患者内的心脏压力。 简而言之，如果在患者体内发生，则该装置检测到急性MR的指示。 该装置还对患者的组织施加电场并测量受电场影响的电参数，例如导纳，阻抗或电导。 然后，该装置基于测量的电参数和急性MR的指示来估计患者内的心脏压力。 在一个示例中，不同的线性相关函数用于根据患者内存在或不存在急性MR将导纳值转换为左心房压（LAP）值。

公开(公告)号：US20120035681A1

公开(公告)日：2012-02-09

申请号：US12853157

申请日：2010-08-09

申请人： Dan E. Gutfinger ,  Fujian Qu ,  Alex Soriano ,  Ryan Rooke ,  Yelena Nabutovsky ,  Riddhi Shah

发明人： Dan E. Gutfinger ,  Fujian Qu ,  Alex Soriano ,  Ryan Rooke ,  Yelena Nabutovsky ,  Riddhi Shah

IPC分类号： A61N1/36

CPC分类号： A61N1/36585 ,  A61B5/0215 ,  A61B5/02158 ,  A61N1/36521 ,  A61N1/36564 ,  A61N1/36578 ,  A61N1/37235 ,  A61N1/37258 ,  A61N1/3962

摘要： Various techniques are provided for use with an implantable medical device for estimating cardiac pressure within a patient based on admittance (or related electrical values such as impedance or conductance) that takes into account the presence of acute MR within the patient. Briefly, the device detects an indication of acute MR, if occurring within the patient. The device also applies electrical fields to tissues of the patient and measures electrical parameters influenced by the electrical field, such as admittance, impedance or conductance. The device then estimates cardiac pressure within the patient based on the measured electrical parameter and the indication of acute MR. In one example, different linear correlation functions are used to convert admittance values to left atrial pressure (LAP) values depending upon the presence or absence of acute MR within the patient.

摘要翻译： 提供了与植入式医疗装置一起使用的各种技术，其基于考虑到患者内急性MR的存在的导纳（或相关的电气值，例如阻抗或电导）来估计患者内的心脏压力。 简而言之，如果在患者体内发生，则该装置检测到急性MR的指示。 该装置还对患者的组织施加电场并测量受电场影响的电参数，例如导纳，阻抗或电导。 然后，该装置基于测量的电参数和急性MR的指示来估计患者内的心脏压力。 在一个示例中，不同的线性相关函数用于根据患者内存在或不存在急性MR将导纳值转换为左心房压（LAP）值。

公开(公告)号：US08706239B2

公开(公告)日：2014-04-22

申请号：US13485404

申请日：2012-05-31

申请人： Rupinder Bharmi ,  Taraneh Ghaffari Farazi ,  Ryan Rooke ,  Stuart Rosenberg ,  Kritika Gupta ,  Riddhi Shah ,  Gene A. Bornzin ,  Wenbo Hou ,  Laurence S. Sloman

发明人： Rupinder Bharmi ,  Taraneh Ghaffari Farazi ,  Ryan Rooke ,  Stuart Rosenberg ,  Kritika Gupta ,  Riddhi Shah ,  Gene A. Bornzin ,  Wenbo Hou ,  Laurence S. Sloman

IPC分类号： A61N1/00

CPC分类号： A61N1/36071 ,  A61B5/029 ,  A61B5/042 ,  A61B5/0538 ,  A61B5/1116 ,  A61B5/4836 ,  A61B5/686 ,  A61B5/7239 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/36185

摘要： Techniques are provided for controlling neurostimulation such as spinal cord stimulation (SCS) using a cardiac rhythm management device (CRMD). In various examples described herein, neurostimulation is delivered to a patient while regional cardiac performance of the heart of the patient is assessed by the CRMD. The delivery of further neurostimulation is adjusted or controlled based, at least in part, on the regional cardiac performance, preferably to enhance positive effects on the heart due to the neurostimulation or to mitigate any negative effects. Regional cardiac performance is assessed based on parameters derived from cardiogenic impedance signals detected along various vectors through the heart.

摘要翻译： 提供了使用心律管理装置（CRMD）来控制神经刺激如脊髓刺激（SCS）的技术。 在本文描述的各种示例中，神经刺激被递送给患者，同时通过CRMD来评估患者心脏的区域心脏性能。 至少部分地基于区域心脏性能来调整或控制进一步神经刺激的递送，优选地由于神经刺激而增强对心脏的积极作用或减轻任何负面影响。 基于通过心脏沿着各种载体检测到的心源性阻抗信号的参数来评估区域心脏性能。