公开(公告)号：US20200345495A1

公开(公告)日：2020-11-05

申请号：US16888322

申请日：2020-05-29

申请人： University of Maryland, Baltimore ,  University of Maryland Medical System LLC

发明人： James Gammie ,  Rachael Quinn ,  Chetan Pasrija

IPC分类号： A61F2/24 ,  A61L27/36

摘要： The present invention provides devices for treating functional mitral regurgitation and methods of use thereof. The devices translocate a subject's mitral valve in an apical direction. The devices thereby treat mitral regurgitation while preserving a subject's original mitral valve and chordae tendinae.

公开(公告)号：US20200306440A1

公开(公告)日：2020-10-01

申请号：US16754382

申请日：2018-10-10

申请人： UNIVERSITY OF MARYLAND, BALTIMORE ,  UNIVERSITY OF MARYLAND MEDICAL SYSTEM, LLC

发明人： Zachary KON ,  Mehrdad GHOREISHI ,  Chetan PASRIJA ,  Bartley GRIFFITH ,  Gregory BITTLE

IPC分类号： A61M1/36 ,  A61M25/00

摘要： Disclosed herein is a bidirectional intravascular cannula, or catheter, that is configured to provide and return blood in a patient bidirectionally. The bidirectional intravascular cannula is configured to reduce or obviate the need for a second cannula, such as currently available unidirectional cannulae, to be placed in a second or opposite direction of flow. Users would include cardiac surgeons, intensivists, vascular surgeons, ER doctors, IR doctors and cardiologist who use peripheral cannulation for ECLS or cardiopulmonary bypass. The cannula allows continued flow to a patient's limb even with the cannula proximally in the vessel. The cannula further allows larger size cannula to be placed without the need for additional distal catheter placement.

公开(公告)号：US20200229805A1

公开(公告)日：2020-07-23

申请号：US16787747

申请日：2020-02-11

申请人： University of Maryland, Baltimore ,  University of Maryland Medical System, LLC

发明人： James S. GAMMIE ,  Rachael QUINN ,  Chetan PASRIJA

IPC分类号： A61B17/00 ,  A61B17/34

摘要： The present invention provides transseptal puncture devices configured to access structures on the left side of the heart from the right side of the heart without requiring open-heart surgery. The devices have adjustable stiffness to enter the vasculature in a flexible, atraumatic fashion, then become rigid once in place to provide a stable platform for penetration of the fossa ovalis. The devices are further configured to controllably and stably extend a needle to puncture the FO. The devices include an indwelling blunt stylus that can extend perpendicularly from the device to increase the accuracy of placement near the fossa ovalis.

公开(公告)号：US20200155132A1

公开(公告)日：2020-05-21

申请号：US16577345

申请日：2019-09-20

申请人： University of Maryland, Baltimore ,  University of Maryland Medical System, LLC

发明人： James S. GAMMIE ,  Rachael QUINN ,  Chetan PASRIJA

IPC分类号： A61B17/00 ,  A61B17/34

摘要： The present invention provides transseptal puncture devices configured to access structures on the left side of the heart from the right side of the heart without requiring open-heart surgery. The devices have adjustable stiffness to enter the vasculature in a flexible, atraumatic fashion, then become rigid once in place to provide a stable platform for penetration of the fossa ovalis. The devices are further configured to controllably and stably extend a needle to puncture the FO. The devices include an indwelling blunt stylus that can extend perpendicularly from the device to increase the accuracy of placement near the fossa ovalis.

公开(公告)号：US20240033082A1

公开(公告)日：2024-02-01

申请号：US17816080

申请日：2022-07-29

申请人： University of Maryland, Baltimore ,  University of Maryland Medical System LLC

发明人： James Gammie ,  Rachael Quinn ,  Chetan Pasrija

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2454 ,  A61F2/2463

摘要： The present invention provides devices for treating functional mitral regurgitation and methods of use thereof. The devices translocate a subject's mitral valve in an apical direction. The devices thereby treat mitral regurgitation while preserving a subject's original mitral valve and chordae tendinae.

公开(公告)号：US11872133B1

公开(公告)日：2024-01-16

申请号：US17816080

申请日：2022-07-29

申请人： University of Maryland, Baltimore ,  University of Maryland Medical System LLC

发明人： James Gammie ,  Rachael Quinn ,  Chetan Pasrija

IPC分类号： A61F2/24

CPC分类号： A61F2/2445 ,  A61F2/2454 ,  A61F2/2463

摘要： The present invention provides devices for treating functional mitral regurgitation and methods of use thereof. The devices translocate a subject's mitral valve in an apical direction. The devices thereby treat mitral regurgitation while preserving a subject's original mitral valve and chordae tendinae.

公开(公告)号：US20190224456A1

公开(公告)日：2019-07-25

申请号：US16256499

申请日：2019-01-24

申请人： University of Maryland, Baltimore ,  University of Maryland Medical System, LLC

发明人： Zachary Kon ,  Bartley P. Griffith ,  Mehrdad Ghoreishi ,  Chetan Pasrija ,  Gregory Bittle

IPC分类号： A61M25/09

摘要： Disclosed herein is a guidewire configured for placement of large bore catheters and cannulae inside of a patient's blood vessels without fluoroscopic guidance. The guidewire, in accordance with certain aspects of an embodiment of the invention, comprises sections of varying stiffness throughout optimally fixed length portions of the guidewire that particularly ease placement of such large bore catheters and cannulae in ECMO applications.