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11.Novel Cyclic Urea Derivatives, Preparation Thereof and Pharmaceutical Use Thereof as Kinase Inhibitors 有权
Title translation: 新型环状尿素衍生物,其制备方法及其药物用途作为激酶抑制剂公开(公告)号:US20090082379A1
公开(公告)日:2009-03-26
申请号:US12173380
申请日:2008-07-15
Applicant: Frank HALLEY , Youssef El-Ahmad , Victor Certal , Corinne Venot , Anne Dagallier , Hartmut Strobel , Kurt Ritter , Sven Ruf
Inventor: Frank HALLEY , Youssef El-Ahmad , Victor Certal , Corinne Venot , Anne Dagallier , Hartmut Strobel , Kurt Ritter , Sven Ruf
IPC: A61K31/506 , C07D401/14 , C07D403/06 , C07D401/06 , C12N5/00 , A61P35/00 , A61K31/444 , C07D403/14 , A61P43/00
CPC classification number: C07D401/14 , C07D401/06 , C07D403/06 , C07D403/14
Abstract: Compounds of formula (I): wherein Ra, Rb, R, X1 and X2 are as defined in the disclosure, pharmaceutical compositions comprising said compounds, processes for making and methods of using the same are provided.
Abstract translation: 式(I)化合物:其中Ra,Rb,R,X1和X2如本公开所定义,提供包含所述化合物的药物组合物,制备方法和使用方法。