Receptor antagonist
    11.
    发明申请
    Receptor antagonist 审中-公开
    受体拮抗剂

    公开(公告)号:US20070117840A1

    公开(公告)日:2007-05-24

    申请号:US10549889

    申请日:2004-03-16

    IPC分类号: A61K31/4704

    CPC分类号: A61K31/4704

    摘要: A compound represented by the formula (I): wherein ring A represents an aromatic ring; X represents a bond, oxygen, NR4 (R4 represents hydrogen, a hydrocarbon group, or a heterocyclic group), or alkylene; R1 represents a hydrocarbon group, or a heterocyclic group; R2 represents —COYR5 (Y represents a bond, alkylene, oxygen, sulfur, or NR6 (R6 represents hydrogen, a hydrocarbon group, or a heterocyclic group), and R5 represents a hydrocarbon group, or a heterocyclic group), a hydrocarbon group, or a heterocyclic group; and R3 represents a hydrocarbon group, a heterocyclic group, optionally substituted hydroxy, optionally substituted amino, or —S(O)nR7 (R7 represents a hydrocarbon group, or a heterocyclic group, and n is 0 to 2), a salt of the compound, or a prodrug or either is useful as an agent for modulating the function of an RFRP receptor.

    摘要翻译: 由式(I)表示的化合物:其中环A表示芳环; X表示键,氧,NR 4(R 4表示氢,烃基或杂环基)或亚烷基; R 1表示烃基或杂环基; R 2表示-COYR 5(Y表示键,亚烷基,氧,硫或NR 6(R 6) SUP>表示氢,烃基或杂环基),R 5表示烃基或杂环基),烃基或杂环基; 和R 3表示烃基,杂环基,任选取代的羟基,任选取代的氨基或-S(O)n R 7 (R 7表示烃基或杂环基,n为0〜2),化合物或前药的盐或其可用作调节其功能的试剂 RFRP受体。

    High-concentration talc masterbatch
    14.
    发明授权
    High-concentration talc masterbatch 有权
    高浓度滑石母料

    公开(公告)号:US06403691B1

    公开(公告)日:2002-06-11

    申请号:US09531448

    申请日:2000-03-20

    IPC分类号: C08K334

    摘要: Disclosed is a high-concentration talc masterbatch comprising: (A) 10 to 60 parts by weight of an elastomer having a melt flow rate of from 0.5 to 150 g/10 min; (B) 40 to 90 parts by weight of talc having an average particle diameter of from 1 to 15 &mgr;m; and (C) 0.01 to 5 parts by weight of a metal soap, based on 100 parts by weight of the sum of the ingredients (A) and (B).

    摘要翻译: 公开了一种高浓度滑石母料,其包含:(A)10至60重量份的熔体流动速率为0.5至150g / 10min的弹性体; (B)40〜90重量份平均粒径为1〜15微米的滑石; 和(C)基于100重量份的成分(A)和(B)的总和,0.01至5重量份的金属皂。