公开(公告)号：US20100168366A1

公开(公告)日：2010-07-01

申请号：US12666482

申请日：2008-06-24

申请人： Taiichi Usui ,  Takeomi Murata ,  Takashi Suzuki ,  Ilpal Jwa ,  Yusuke Ohba ,  Tomoki Hamamoto ,  Toshitada Noguchi

发明人： Taiichi Usui ,  Takeomi Murata ,  Takashi Suzuki ,  Ilpal Jwa ,  Yusuke Ohba ,  Tomoki Hamamoto ,  Toshitada Noguchi

IPC分类号： C08F251/00

CPC分类号： C08G69/48 ,  A61K31/7012 ,  A61K47/645 ,  C08G69/04 ,  C08G69/10 ,  C08G69/40

摘要： A polymer containing an N-linked sialo-glycan wherein a sialo-glycan is condensed to a γ-polyglutamic acid using a chemical compound having an amino group on one end and a carboxyl group on another end and represented by the structural formula (I). Formula (I) (In the formula, Z means a hydroxy group or a residue represented by the formula (II), and n represents an integer of 10 or more, with the proviso that any one or more of the Z's is represented by the formula in (II).) Formula (II) (In the formula, X means a hydroxy group or an acetylamino group, Y1 and Y2 mean a hydroxyl group or an N-acetylneuraminic acid residue, L means a hydrocarbon, an m represents 0 or an integer of 1 or 2, with the proviso that Y1 and Y2 are not the same.)

摘要翻译： 一种含有N-连接的唾液酸聚糖的聚合物，其中唾液酸聚糖用一端具有氨基和另一端的羧基并由结构式（I）表示的化合物缩合成γ-聚谷氨酸， 。 式（I）（式中，Z表示羟基或式（II）表示的残基，n表示10以上的整数，条件是Z中的任一个以上可以由 式（II）中，式（II）（式中，X表示羟基或乙酰氨基，Y1和Y2表示羟基或N-乙酰神经氨酸残基，L表示烃，m表示0 或1或2的整数，条件是Y1和Y2不相同。）