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11.DUAL SPECIFIC BINDING PROTEINS DIRECTED AGAINST IL-1 and/or IL-17 有权
Title translation: 针对IL-1和/或IL-17的双特异性结合蛋白公开(公告)号:US20140356281A1
公开(公告)日:2014-12-04
申请号:US14323627
申请日:2014-07-03
Applicant: AbbVie Inc.
Inventor: Tariq Ghayur , JiJie Gu , Maria Harris , Carrie Goodreau , Sonal Saluja
IPC: C07K16/24 , A61K39/395 , A61K45/06 , A61K47/48
CPC classification number: C07K16/468 , A61K39/3955 , A61K45/06 , A61K47/6845 , A61K47/6879 , C07K16/244 , C07K16/245 , C07K2317/31 , C07K2317/626 , C07K2317/64 , C07K2317/76 , C07K2317/92 , C07K2317/94 , C07K2319/00 , G01N33/6869 , G01N2333/54 , G01N2333/545
Abstract: Engineered multivalent and multispecific binding proteins that bind IL-1β and/or IL-17 are provided, along with methods of making and uses in the prevention, diagnosis, and/or treatment of disease.
Abstract translation: 结合IL-1和bgr的工程化多价和多特异性结合蛋白 和/或IL-17,以及在预防,诊断和/或治疗疾病中的制备和用途的方法。