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公开(公告)号：US20220317479A1
公开(公告)日：2022-10-06
申请号：US17805832
申请日：2022-06-07
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Gordon Frederick MACCABEE , Ferry WIDJAJA , Amitava GUPTA
Abstract: A contact lens may include a body of contact lens material extending between a first surface and a second surface. An electromechanical component may be supported in the contact lens material between the first surface and the second surface. A support comprising a plurality of pillars may be formed of the contact lens material and may extend from at least one of the first surface and the second surface to the electromechanical component.
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公开(公告)号：US20220299795A1
公开(公告)日：2022-09-22
申请号：US17806326
申请日：2022-06-10
Applicant: ACUCELA INC.
Inventor： Beat WYSS , Jean-Noël FEHR , Glenn NORONHA , Karim HAROUD , Julien SAUVET , Hans BERNHARD , Christian OGGENFUSS , Amitava GUPTA , Ryo KUBOTA
Abstract: A soft contact lens comprises a plurality of light sources coupled to a plurality of optical elements. The plurality of light sources and the plurality of optical elements are embedded in a soft contact lens material. Each of said plurality of optical elements generates an image focused in front of a peripheral retina of a wearer. In some embodiments, each of the images is focused at a distance in front of the peripheral retina at a location, and each of the images comprises a depth of focus and a spatial resolution. The depth of focus can be less than the distance, and the spatial resolution greater than a spatial resolution of the peripheral retina at the location.
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公开(公告)号：US20220155616A1
公开(公告)日：2022-05-19
申请号：US17650134
申请日：2022-02-07
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Nabin JOSHI , Arkady SELENOW , Steven ALI , Stefan BAUER , Jean-Noël FEHR , Moritz HAEBERLI , Patrizia WEBER , Julien SAUVET , Amitava GUPTA
Abstract: An apparatus to treat refractive error of the eye comprises one or more optics configured to project stimuli comprising out of focus images onto the peripheral retina outside the macula. While the stimuli can be configured in many ways, in some embodiments the stimuli are arranged to decrease interference with central vison such as macular vision. The stimuli can be out of focus images may comprise an amount of defocus within a range from about 3 Diopters (“D”) to about 6 D. In some embodiments, the brightness of the stimuli is greater than a brightness of background illumination by an appropriate amount such as at least 3 times the background brightness. In some embodiments, each of a plurality of stimuli comprises a spatial frequency distribution with an amplitude profile having spatial frequencies within a range from about range of 1×10−1 to 2.5×101 cycles per degree.
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公开(公告)号：US20210263336A1
公开(公告)日：2021-08-26
申请号：US17250278
申请日：2019-07-03
Applicant: ACUCELA INC.
Inventor： Amitava GUPTA , Ryo KUBOTA
Abstract: A contact lens configured to decrease dark adaptation comprises one or more LEDs and directs light from the LED away from the fovea and toward the parafovea or perifoveal regions of the retain. In some embodiments, soft contact lens embedded with one or more arrays of microLEDs and electronics operating the LEDs is configured to be worn at night in order to inhibit dark adaptation and reduce oxygen consumption by the rods. The contact lens may be made of a single layer of a contact lens material or multiple layers sandwiching a flexible transparent plastic layer comprising the electronics and the LED arrays. The contact lens may be made of a hydrophilic hydrogel material that is biocompatible to the human cornea, or a silicone hydrogel material. The contact lens may be spherical and may provide refractive correction to the eye of the wearer.
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公开(公告)号：US20210069524A1
公开(公告)日：2021-03-11
申请号：US17052906
申请日：2019-05-03
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Amitava GUPTA
Abstract: A source of light energy such as a source of violet light energy is coupled to a structure configured to contact the eye. The light source and structure are arranged to provide therapeutic amounts of violet light energy to the eye in order to inhibit the progression of refractive error such as myopia. The light source can be configured in many ways and may comprise a radioisotope and a phosphorescent material. The structure configured to contact the eye may comprise a contact lens or an implant.
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Patent Agency Ranking
公开(公告)号：US20240411155A1
公开(公告)日：2024-12-12
申请号：US18812767
申请日：2024-08-22
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Philip M. BUSCEMI , Amitava GUPTA , Stefan BAUER , Benjamin CROOK , Julien SAUVET
Abstract: An apparatus to treat refractive error of an eye comprises an optic comprising an optical zone and a peripheral defocus optical structure to form images of a plurality of stimuli anterior or posterior to a peripheral portion of a retina of the eye. In some embodiments, the peripheral defocus optical structure located outside the optical zone. In some embodiments, the peripheral defocus optical structure comprises optical power to focus light to a different depth of the eye than the optical zone. In some embodiments, the optic comprises one or more of a lens, an optically transparent substrate, a beam splitter, a prism, or an optically transmissive support.
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公开(公告)号：US20240264472A1
公开(公告)日：2024-08-08
申请号：US18637705
申请日：2024-04-17
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Amitava GUPTA
CPC classification number: G02C7/083 , G02F1/294 , G02C2202/24
Abstract: An apparatus to treat refractive error of an eye comprises an electroactive component configured to switch between a light scattering or optical power providing configuration to treat refractive error of the eye and a substantially transparent configuration to allow normal viewing. The electroactive component can be located on the lens away from a central axis of the lens to provide light to a peripheral region of the retina to decrease the progression of myopia. The electroactive component can be located on the lens away from the central axis of the lens in order for the wearer to view objects through an optical zone while the electroactive component scatters light. The electroactive component can be configured to switch to the substantially transparent configuration to allow light to pass through the electroactive component and to allow the lens to refract light to correct vision and allow normal viewing through the lens.
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公开(公告)号：US20230241410A1
公开(公告)日：2023-08-03
申请号：US18163376
申请日：2023-02-02
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Benjamin CROOK , Stefan BAUER , Philip M. BUSCEMI , Amitava GUPTA , Jonas GERMANN
IPC: A61N5/06
CPC classification number: A61N5/0622 , A61N2005/0648 , A61N2005/0651
Abstract: A wearer adjustable apparatus is configured for a wearer to view an object and adjust stimuli projected into the eye by adjusting the location of the projection optics, for example with movement of the projection optics relative to one or more components of a support such as an eyeglass frame. In some embodiments, the projection system comprises an adjustable retainer for the wearer to adjust first active projection elements coupled to a first support in front of a first eye in relation to second projection optics coupled to a second support in front of a second eye of the wearer. In some embodiments, the apparatus comprises oculars comprising the projection optics and corrective lenses configured for the wearer to adjust positions of the lenses and projection optics in front of the wearer's eyes in order to project therapeutic spots onto a desired location relative to the wearer's retinas.
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公开(公告)号：US20230089006A1
公开(公告)日：2023-03-23
申请号：US18051804
申请日：2022-11-01
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Gordon Frederick MACCABEE , Ferry WIDJAJA , Amitava GUPTA
Abstract: A contact lens may include a body of contact lens material extending between a first surface and a second surface. An electromechanical component may be supported in the contact lens material between the first surface and the second surface. A support comprising a plurality of pillars may be formed of the contact lens material and may extend from at least one of the first surface and the second surface to the electromechanical component.
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公开(公告)号：US20230026753A1
公开(公告)日：2023-01-26
申请号：US17936263
申请日：2022-09-28
Applicant: ACUCELA INC.
Inventor： Ryo KUBOTA , Philip M. BUSCEMI , Matthias PFISTER , Stephan WYDER , Amitava GUPTA
IPC: A61B3/10 , G01B9/02091
Abstract: An OCT axial length measurement device is configured to measure an area of the retina within a range from about 0.05 mm to about 2.0 mm. The area can be measured with a scanned measurement beam or plurality of substantially fixed measurement beams. The OCT measurement device may comprise a plurality of reference optical path lengths, in which a first optical path length corresponds to a first position of a cornea, and a second optical path length corresponds to a second position of the retina, in which the axial length is determined based on a difference between the first position and the second position. An axial length map can be generated to determine alignment of the eye with the measurement device and improve accuracy and repeatability of the measurements. In some embodiments, the OCT measurement device comprises a swept source vertical cavity surface emitting laser (“VCSEL”).
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