公开(公告)号：US20230363638A1

公开(公告)日：2023-11-16

申请号：US18040186

申请日：2021-08-10

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Stephan WYDER ,  Philip M. BUSCEMI ,  Matthias PFISTER ,  Cyril STOLLER

IPC: A61B3/10

CPC classification number: A61B3/102 ,  G01B9/02091

Abstract: An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. Measurement data may be processed using a decurving process to enhance the resolution of the ILM layer and provide improved determinations of retinal thickness.

公开(公告)号：US20210235984A1

公开(公告)日：2021-08-05

申请号：US17248850

申请日：2021-02-10

Applicant: ACUCELA INC.

Inventor： Lukas SCHEIBLER ,  Matthias PFISTER ,  Urban SCHNELL ,  Stefan TROLLER ,  Ryo KUBOTA

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/12 ,  A61B5/00 ,  G01B9/02

Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.

公开(公告)号：US20210127969A1

公开(公告)日：2021-05-06

申请号：US17247630

申请日：2020-12-18

Applicant: ACUCELA INC.

Inventor： Christian OGGENFUSS ,  Karim HAROUD ,  Lukas SCHEIBLER ,  Matthias PFISTER ,  Urban SCHNELL ,  Stefan TROLLER ,  Ryo KUBOTA ,  Philip M. BUSCEMI

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/13

Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.

公开(公告)号：US20240108216A1

公开(公告)日：2024-04-04

申请号：US18525549

申请日：2023-11-30

Applicant: ACUCELA INC.

Inventor： Lukas SCHEIBLER ,  Matthias PFISTER ,  Urban SCHNELL ,  Stefan TROLLER ,  Ryo KUBOTA

IPC: A61B3/10 ,  A61B3/00 ,  A61B3/12 ,  A61B5/00 ,  G01B9/02

CPC classification number: A61B3/102 ,  A61B3/0008 ,  A61B3/0025 ,  A61B3/10 ,  A61B3/1005 ,  A61B3/1225 ,  A61B5/0013 ,  G01B9/02 ,  A61B2505/07 ,  A61B2560/0425 ,  A61B2560/0431 ,  A61B2560/0456 ,  A61B2576/00

Abstract: Improved optical coherence tomography systems and methods to measure thickness of the retina are presented. The systems may be compact, handheld, provide in-home monitoring, allow the patient to measure himself or herself, and be robust enough to be dropped while still measuring the retina reliably.

公开(公告)号：US20230363640A1

公开(公告)日：2023-11-16

申请号：US18317549

申请日：2023-05-15

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Stephan WYDER ,  Philip M. BUSCEMI ,  Matthias PFISTER ,  Alexander HOLZER

IPC: A61B3/10 ,  G01B9/02004 ,  G01B9/02091 ,  A61B3/12

CPC classification number: A61B3/102 ,  G01B9/02004 ,  G01B9/02091 ,  A61B3/1225

Abstract: An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. The scan pattern is a continuous pattern that includes a plurality of lobes. The measurement beam may be caused to move on the retina by the motion of a mirror that intercepts and redirects the measurement beam. The mirror position may be altered by the application of a drive signal to one or more actuators that respond to the drive signal by rotating the mirror about an axis or axes.

公开(公告)号：US20230206440A1

公开(公告)日：2023-06-29

申请号：US18177560

申请日：2023-03-02

Applicant: ACUCELA INC.

Inventor： Stephan WYDER ,  Matthias PFISTER ,  Cyril STOLLER ,  Philip M. BUSCEMI

IPC: G06T7/00 ,  G06T7/11 ,  G06T3/00 ,  G06N3/08 ,  G16H30/40

CPC classification number: G06T7/0012 ,  G06T7/11 ,  G06T3/00 ,  G06N3/08 ,  G16H30/40 ,  G06T2207/20084 ,  G06T2207/10101 ,  G06T2207/30041 ,  G06T2207/20081 ,  G06V2201/03 ,  G06V10/82

Abstract: A neural network is trained to segment interferogram images. A first plurality of interferograms are obtained, where each interferograms corresponds to data acquired by an OCT system using a first scan pattern, annotating each of the plurality of interferograms to indicate a tissue structure of a retina, training a neural network using the plurality of interferograms and the annotations, inputting a second plurality of interferograms corresponding to data acquired by an OCT system using a second scan pattern and obtaining an output of the trained neural network indicating the tissue structure of the retina that was scanned using the second scan pattern. The system and methods may instead receive a plurality of A-scans and output a segmented image corresponding to a plurality of locations along an OCT scan pattern.

公开(公告)号：US20220257112A1

公开(公告)日：2022-08-18

申请号：US17662582

申请日：2022-05-09

Applicant: ACUCELA INC.

Inventor： Ryo KUBOTA ,  Stephan WYDER ,  Philip M. BUSCEMI ,  Matthias PFISTER ,  Alexander HOLZER

IPC: A61B3/10 ,  G01B9/02004 ,  G01B9/02091 ,  A61B3/12

Abstract: An OCT system for measuring a retina as part of an eye health monitoring and diagnosis system. The OCT system includes an OCT interferometer, where the interferometer comprises a light source or measurement beam and a scanner for moving the beam on the retina of a patient's eye, and a processor configured to execute instructions to cause the scanner to move the measurement beam on the retina in a scan pattern. The scan pattern is a continuous pattern that includes a plurality of lobes. The measurement beam may be caused to move on the retina by the motion of a mirror that intercepts and redirects the measurement beam. The mirror position may be altered by the application of a drive signal to one or more actuators that respond to the drive signal by rotating the mirror about an axis or axes.

公开(公告)号：US20220084197A1

公开(公告)日：2022-03-17

申请号：US17444806

申请日：2021-08-10

Applicant: ACUCELA INC.

Inventor： Stephan WYDER ,  Matthias PFISTER ,  Cyril STOLLER ,  Philip M. BUSCEMI

IPC: G06T7/00 ,  G06T7/11 ,  G06T3/00 ,  G06N3/08 ,  G16H30/40

Abstract: A neural network is trained to segment interferogram images. A first plurality of interferograms are obtained, where each interferograms corresponds to data acquired by an OCT system using a first scan pattern, annotating each of the plurality of interferograms to indicate a tissue structure of a retina, training a neural network using the plurality of interferograms and the annotations, inputting a second plurality of interferograms corresponding to data acquired by an OCT system using a second scan pattern and obtaining an output of the trained neural network indicating the tissue structure of the retina that was scanned using the second scan pattern. The system and methods may instead receive a plurality of A-scans and output a segmented image corresponding to a plurality of locations along an OCT scan pattern.