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    JUMPING ROBOT
    11.
    发明申请
    JUMPING ROBOT 有权
    摔跤机器人

    公开(公告)号：US20130282174A1

    公开(公告)日：2013-10-24

    申请号：US13832284

    申请日：2013-03-15

    Applicant: Ning Xi ,  Jianguo Zhao ,  Bingtuan Gao ,  Jing Xu ,  Matt Mutka ,  Li Xiao

    Inventor： Ning Xi ,  Jianguo Zhao ,  Bingtuan Gao ,  Jing Xu ,  Matt Mutka ,  Li Xiao

    IPC: B25J9/16

    CPC classification number: B25J9/1682 ,  B25J9/104 ,  Y10S901/01

    Abstract: A jumping robot is provided. In another aspect, a jumping robot weighs less than 50 grams, jumps at least 20 cm high and has a maximum linear dimension of 10 cm. A further aspect provides a robot that employs an electromagnetic actuator that actuates at least two of: jumping, steering, self-righting, and/or mid-air orientation control.

    Abstract translation: 提供跳跃机器人。 在另一方面，跳跃机器人重量小于50克，跳跃至少20厘米高，最大直线尺寸为10厘米。 另一方面提供了一种使用致动器的电磁致动器的机器人，其致动：跳跃，转向，自对准和/或空中取向控制中的至少两个。

    Allocation of Resources in a Communication System
    12.
    发明申请
    Allocation of Resources in a Communication System 有权
    通信系统资源配置

    公开(公告)号：US20130237268A1

    公开(公告)日：2013-09-12

    申请号：US13885010

    申请日：2010-11-12

    Applicant: Yong Teng ,  Kari Veikko Horneman ,  Xiaojin Zheng ,  Jiang Wang ,  Jing Xu

    Inventor： Yong Teng ,  Kari Veikko Horneman ,  Xiaojin Zheng ,  Jiang Wang ,  Jing Xu

    IPC: H04W72/08

    CPC classification number: H04W72/082 ,  H04L5/0032 ,  H04L5/0058 ,  H04W52/346

    Abstract: A method and an apparatus for resource allocation in a local wireless node of a system of a plurality of local wireless nodes is disclosed. An inner circle subgradient resource allocation iteration is performed based on information received from at least one other wireless node of the system and an iteration parameter until a convergent result. An updated iteration parameter is provided by of at least one outer circle subgradient iteration based on the convergent result of the inner circle subgradient resource allocation iteration. The inner circle subgradient resource allocation iteration is then repeated at least once using the updated iteration parameter until a convergent result. Resources are then allocated based on the iterations.

    Abstract translation: 公开了一种在多个本地无线节点的系统的本地无线节点中进行资源分配的方法和装置。 基于从系统的至少一个其他无线节点接收的信息和迭代参数来执行内圈子梯度资源分配迭代，直到收敛结果为止。 基于内圈子梯度资源分配迭代的收敛结果，更新的迭代参数由至少一个外圈子梯度迭代提供。 然后使用更新的迭代参数至少重复内圈次级资源分配迭代，直到收敛结果。 然后根据迭代分配资源。

    GENERATING A PREDICTIVE MODEL FROM MULTIPLE DATA SOURCES
    13.
    发明申请
    GENERATING A PREDICTIVE MODEL FROM MULTIPLE DATA SOURCES 有权
    从多个数据源生成预测模型

    公开(公告)号：US20120239613A1

    公开(公告)日：2012-09-20

    申请号：US13048536

    申请日：2011-03-15

    Applicant: Marius I. Danciu ,  Fan Li ,  Michael McRoberts ,  Jing-Yun Shyr ,  Damir Spisic ,  Jing Xu

    Inventor： Marius I. Danciu ,  Fan Li ,  Michael McRoberts ,  Jing-Yun Shyr ,  Damir Spisic ,  Jing Xu

    IPC: G06F7/00 ,  G06F17/00 ,  G06F17/30

    CPC classification number: G06Q10/06

    Abstract: Techniques are disclosed for generating an ensemble model from multiple data sources. In one embodiment, the ensemble model is generated using a global validation sample, a global holdout sample and base models generated from the multiple data sources. An accuracy value may be determined for each base model, on the basis of the global validation dataset. The ensemble model may be generated from a subset of the base models, where the subset is selected on the basis of the determined accuracy values.

    Abstract translation: 公开了用于从多个数据源生成集合模型的技术。 在一个实施例中，使用全局验证样本，全局保持样本和从多个数据源生成的基本模型来生成集合模型。 可以基于全局验证数据集为每个基本模型确定精度值。 集合模型可以从基本模型的子集生成，其中基于确定的精度值选择子集。

    Lens barrel assembly for a camera
    17.
    发明授权
    Lens barrel assembly for a camera 有权
    相机镜头组件

    公开(公告)号：US07769284B2

    公开(公告)日：2010-08-03

    申请号：US11565518

    申请日：2006-11-30

    Applicant: Tony K. Tang ,  Jing Xu ,  Roman C. Gutierrez

    Inventor： Tony K. Tang ,  Jing Xu ,  Roman C. Gutierrez

    IPC: G01B3/00 ,  G01B13/00

    CPC classification number: G03B5/00 ,  G02B13/009 ,  G02B15/10 ,  G03B3/00 ,  G03B17/04 ,  Y10T29/49117

    Abstract: A lens barren assembly for a camera is disclosed. The lens barrel assembly comprises a lens barrel, at least one optical element disposed within the lens barrel, and an actuator configured to move the optical element. The actuator can be disposed entirely or partially within the lens barrel. The actuator can be a MEMS actuator, such as a MEMS actuator that is formed at least partially of silicon. The optical element can be a lens.

    Abstract translation: 公开了一种用于相机的透镜残余组件。 镜筒组件包括透镜镜筒，设置在透镜镜筒内的至少一个光学元件以及被配置为移动光学元件的致动器。 致动器可以完全地或部分地设置在镜筒内。 致动器可以是MEMS致动器，例如至少部分地由硅形成的MEMS致动器。 光学元件可以是透镜。

    Optical system with plano convex lens
    18.
    发明授权
    Optical system with plano convex lens 有权
    带平凸透镜的光学系统

    公开(公告)号：US07663817B1

    公开(公告)日：2010-02-16

    申请号：US11625204

    申请日：2007-01-19

    Applicant: Jing Xu ,  Roman C. Gutierrez

    Inventor： Jing Xu ,  Roman C. Gutierrez

    IPC: G02B7/02

    CPC classification number: G02B7/102

    Abstract: An optical system for a miniature camera is disclosed. The optical system can have a lens holder including mounting features to position a plurality of lenses. The mounting features can include mounting features that are configured to position a first plastic lens proximate an aperture end portion of the lens holder and/or mounting features that are configured to position a glass plano-convex lens along an optical path through an interior of the lens holder with a substantially planar surface of the glass plano-convex lens positioned toward the aperture end portion of the lens holder.

    Abstract translation: 公开了一种用于微型照相机的光学系统。 光学系统可以具有透镜架，其包括安装特征以定位多个透镜。 安装特征可以包括安装特征，其被配置成将第一塑料透镜靠近透镜保持器的孔端部定位和/或安装特征，其被配置为沿着光路定位玻璃平凸透镜，穿过其内部 透镜保持器，其具有朝向透镜保持器的孔端部定位的玻璃平凸透镜的基本平坦的表面。

    Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo
    19.
    发明申请
    Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo 有权
    重组人EPO-Fc融合蛋白具有延长的半衰期和增强体内红细胞生成活性

    公开(公告)号：US20070178112A1

    公开(公告)日：2007-08-02

    申请号：US11340661

    申请日：2006-01-27

    Applicant: Haitao Wang ,  Yong Du ,  Rui Zhang ,  Jing Xu ,  Longbin Liu

    Inventor： Haitao Wang ,  Yong Du ,  Rui Zhang ,  Jing Xu ,  Longbin Liu

    IPC: A61K39/395 ,  C12P21/06 ,  C07K16/46 ,  C07H21/04 ,  C12N5/06

    CPC classification number: C07K14/505 ,  A61K9/0019 ,  A61K38/00 ,  A61K47/6811 ,  C07K2317/53 ,  C07K2319/30

    Abstract: A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has a prolonged half-life in vivo in comparison to naturally occurring or recombinant native human erythropoietin. In one embodiment of the invention, the protein has a half-life in vivo at least three fold higher than native human erythropoietin. The fusion protein also exhibits enhanced erythropoietic bioactivity in comparison to native human erythropoietin. In one embodiment, the fusion protein comprises the complete peptide sequence of a human erythropoietin (EPO) molecule and the peptide sequence of an Fc fragment of human immunoglobulin IgG1. The Fc fragment in the fusion protein includes the hinge region, CH2 and CH3 domains of human immunoglobulin IgG1. The EPO molecule may be linked directly to the Fc fragment to avoid extraneous peptide linkers and lessen the risk of an immunogenic response when administered in vivo. In one embodiment the hinge region is a human Fc fragment variant having a non-cysteine residue at amino acid 6. The invention also relates to nucleic acid and amino acid sequences encoding the fusion protein and transfected cell lines and methods for producing the fusion protein. The invention further includes pharmaceutical compositions comprising the fusion protein and methods of using the fusion protein and/or the pharmaceutical compositions, for example to stimulate erythropoiesis in subjects in need of therapy.

    Abstract translation: 描述了包含与免疫球蛋白肽部分连接的人促红细胞生成素肽部分的重组融合蛋白。 与天然存在的或重组的天然人促红细胞生成素相比，融合蛋白在体内具有延长的半衰期。 在本发明的一个实施方案中，蛋白质的体内半衰期比天然人促红细胞生成素高至少三倍。 与天然人促红细胞生成素相比，融合蛋白也表现出增强的红细胞生物活性。 在一个实施方案中，融合蛋白包含人促红细胞生成素（EPO）分子的完整肽序列和人免疫球蛋白IgG1的Fc片段的肽序列。 融合蛋白中的Fc片段包括人免疫球蛋白IgG1的铰链区，CH2和CH3结构域。 EPO分子可以直接连接到Fc片段，以避免外来的肽接头并且当在体内施用时减轻免疫原性应答的风险。 在一个实施方案中，铰链区是在氨基酸6具有非半胱氨酸残基的人Fc片段变体。本发明还涉及编码融合蛋白和转染细胞系的核酸和氨基酸序列以及用于产生融合蛋白的方法。 本发明还包括包含融合蛋白的药物组合物和使用融合蛋白和/或药物组合物的方法，例如刺激需要治疗的受试者的红细胞生成。

    Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo
    20.
    发明授权
    Recombinant human EPO-Fc fusion proteins with prolonged half-life and enhanced erythropoietic activity in vivo 有权

    公开(公告)号：US10117949B2

    公开(公告)日：2018-11-06

    申请号：US12162320

    申请日：2007-01-25

    Applicant: Haitao Wang ,  Yong Du ,  Rui Zhang ,  Jing Xu ,  Longbin Liu

    Inventor： Haitao Wang ,  Yong Du ,  Rui Zhang ,  Jing Xu ,  Longbin Liu

    IPC: C07K14/505 ,  A61K38/18 ,  A61K39/00 ,  A61K47/48 ,  A61K38/00

    Abstract: A recombinant fusion protein comprising a human erythropoietin peptide portion linked to an immunoglobulin peptide portion is described. The fusion protein has a prolonged half-life in vivo in comparison to naturally occurring or recombinant native human erythropoietin. In one embodiment of the invention the protein has a half-life in vivo at least three fold higher than native human erythropoietin. The fusion protein also exhibits enhanced erythropoietic bioactivity in comparison to native human erythropoietin. In one embodiment, the fusion protein comprises the complete peptide sequence of a human erythropoietin (EPO) molecule and the peptide sequence of an Fc fragment of human immunoglobulin IgG1. The Fc fragment in the fusion protein includes the hinge region, CH2 and CH3 domains of human immunoglobulin IgG1. The EPO molecule may be linked directly to the Fc fragment to avoid extraneous peptide linkers and lessen the risk of an immunogenic response when administered in vivo. In one embodiment the hinge region is a human Fc fragment variant having a non-cysteine residue at amino acid 6. The invention also relates to nucleic acid and amino acid sequences encoding the fusion protein and transfected cell lines and methods for producing the fusion protein. The invention further includes pharmaceutical compositions comprising the fusion protein and methods of using the fusion protein and/or the pharmaceutical compositions, for example to stimulate erythropoiesis in subjects in need of therapy.

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