公开(公告)号：US10883125B2

公开(公告)日：2021-01-05

申请号：US16392837

申请日：2019-04-24

Applicant: AJINOMOTO CO., INC.

Inventor： Miku Toyazaki ,  Keita Fukui

IPC: C12P7/22 ,  C12N9/02 ,  C12P7/24 ,  C12N9/12

Abstract: A method is described for producing an objective substance, for example, an aldehyde such as vanillin. The objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an ability to produce the objective substance, wherein the microorganism has been modified to have a specific carboxylic acid reductase (CAR) gene, such as a Gordonia CAR gene, Novosphingobium CAR gene, or Coccomyxa CAR gene.

公开(公告)号：US20190249207A1

公开(公告)日：2019-08-15

申请号：US16392837

申请日：2019-04-24

Applicant: AJINOMOTO CO., INC.

Inventor： Miku Toyazaki ,  Keita Fukui

IPC: C12P7/24 ,  C12N9/02 ,  C12N9/12

CPC classification number: C12P7/24 ,  C12N9/0008 ,  C12N9/1205 ,  C12Y102/07005

Abstract: A method is described for producing an objective substance, for example, an aldehyde such as vanillin. The objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an ability to produce the objective substance, wherein the microorganism has been modified to have a specific carboxylic acid reductase (CAR) gene, such as a Gordonia CAR gene, Novosphingobium CAR gene, or Coccomyxa CAR gene.

公开(公告)号：US20190161776A1

公开(公告)日：2019-05-30

申请号：US16200011

申请日：2018-11-26

Applicant: AJINOMOTO CO., INC.

Inventor： Benjamin Mijts ,  Christine Roche ,  Rekha Murali ,  Sayaka Asari ,  Keita Fukui ,  Miku Toyazaki ,  Keiko Noguchi

IPC: C12P7/24 ,  C12N9/10 ,  C12N9/06 ,  C12R1/46 ,  C12R1/15 ,  C12R1/19

Abstract: A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism that is able to produce the objective substance, which microorganism has been modified so that the activity of an enzyme involved in SAM cycle (SAM cycle enzyme) is increased.