公开(公告)号：US20200317776A1

公开(公告)日：2020-10-08

申请号：US16835140

申请日：2020-03-30

Applicant: Alector LLC

Inventor： Tina SCHWABE ,  Eric BROWN ,  Philip KONG ,  Ilaria TASSI ,  Seung-Joo LEE ,  Arnon ROSENTHAL ,  Robert PEJCHAL ,  Nels P. NIELSON

IPC: C07K16/28 ,  A61P25/28

Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a TREM2 protein, e.g., a mammalian TREM2 or human TREM2, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.

公开(公告)号：US20190330335A1

公开(公告)日：2019-10-31

申请号：US15766363

申请日：2016-10-06

Applicant: ALECTOR LLC

Inventor： Tina SCHWABE ,  Francesca AVOGADRI-CONNORS ,  Helen LAM ,  Ilaria TASSI ,  Seung-Joo LEE ,  Arnon ROSENTHAL

IPC: C07K16/28 ,  A61P25/28

Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a TREM2 protein, e.g., a mammalian TREM2 or human TREM2, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.