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11.HEPCIDIN, HEPCIDIN ANTAGONISTS AND METHODS OF USE 审中-公开
Title translation: HEPCIDIN,HEPCIDIN ANTAGONISTS AND METHODS OF USE公开(公告)号:US20140286953A1
公开(公告)日:2014-09-25
申请号:US14103351
申请日:2013-12-11
Applicant: Amgen Inc.
Inventor: Barbra Sasu , Mitsuru Haniu , Thomas Charles Boone , Xiao-juan Bi , Grace Ki Jeong Lee , Tara Arvedson , Aaron George Winters , Keegan Cooke , Jackie Z. Sheng
IPC: C07K16/26 , A61K38/18 , G01N33/74 , A61K39/395
CPC classification number: C07K16/26 , A61K38/1816 , A61K39/3955 , A61K2039/505 , C07K14/575 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/92 , C12N15/1136 , C12N2310/111 , C12N2310/14 , C12N2310/53 , G01N33/74 , A61K2300/00
Abstract: The invention relates to purified, correctly folded hepcidin, antibodies that bind hepcidin, and methods of making and using such materials. Also provide are methods of treated hepcidin-related disorders.
Abstract translation: 本发明涉及纯化的,正确折叠的铁调素,结合铁调素的抗体,以及制备和使用这些材料的方法。 还提供了治疗的铁调素相关病症的方法。