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公开(公告)号：US20240017075A1
公开(公告)日：2024-01-18
申请号：US18221373
申请日：2023-07-12
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Hyun-Joo Park , Yagna Pathak
IPC: A61N1/36
CPC classification number: A61N1/36189 , A61N1/36139 , A61N1/36071
Abstract: Devices and methods to effectuate waveform distortion adjusted stimulation therapy of tissue, based on an inverse model of the tissue, are disclosed. In some aspects a linear model of an electrode used to delivery therapy and of the tissue is determined. Parameter values of the linear model may be determined based on measuring voltage feedback during application of stimulation and/or measurement waveforms. The parameter values of the linear model of the electrode and tissue may be used to determine a forward model of the electrical response of the tissue. From the forward model, an inverse model of the tissue may be determined and the inverse model can be used to modify or filter a stimulation waveform to reduce waveform distortion caused by tissue, such as tissue primitive and/or tissue capacitance. Accordingly, providing therapy with the filtered waveform may have increased efficacy by accounting for and adjusting for waveform distortion.
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12.发明公开公开(公告)号：US20230240760A1
公开(公告)日：2023-08-03
申请号：US18131131
申请日：2023-04-05
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Yagna Pathak , Hyun-Joo Park , Simeng Zhang , Anahita Kyani , Erika Ross , Dehan Zhu , Douglas Lautner
CPC classification number: A61B34/20 , G06T7/73 , A61N1/0534 , G16H30/40 , G16H20/40 , G16H50/20 , G06V10/40 , G06F18/2148 , A61B2090/374
Abstract: The present disclosure provides systems and methods for estimating an orientation of an implanted deep brain stimulation (DBS) lead. Such methods include generating an initial image dataset, down-sampling a respective image or adding noise to images of the subset of the initial image dataset, and re-slicing at least a subset of the modified image dataset along an alternative primary imaging axis, to generate an integrated image dataset. The method also include partitioning the integrated image dataset into a preliminary training image dataset and a testing image dataset, and re-sizing at least a subset of the preliminary training image dataset with a localized field of view around a depicted DBS lead, to generate a training image dataset. The method further includes training a machine-learning model using the training image dataset, and executing the trained machine-learning model to estimate, during a DBS implantation procedure, an orientation of a subject implanted DBS lead.
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公开(公告)号：US20230218900A1
公开(公告)日：2023-07-13
申请号：US17574542
申请日：2022-01-12
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Hyun-Joo Park , Yagna Pathak , Hongxuan Zhang , Anahita Kyani , Erika Ross , Jeffrey Urbanski
CPC classification number: A61N1/36071 , A61N1/36062 , A61N1/36139 , A61N1/375
Abstract: Devices and methods to effectuate closed loop electrical stimulation of nerve tissue, based on feedback data, to mitigate pain of a patient are disclosed. Feedback data corresponding to bioelectric signals of neurons stimulated by stimulation pulses may be received and analyzed. Based on receipt of the feedback data, it may be determined to modify one or more stimulation parameters, corresponding to the stimulation pulses, to enhance an efficacy of the stimulation pulses at blocking generation and/or propagation of one or more pain signals through a neuroanatomy of the patient. Subsequent and additional stimulation pulses may be provided based on a modified set of stimulation parameters and configured to enhance attenuation of generation and/or transmission of pain signals through the neuroanatomy of the patient to ultimately reduce a level of pain experienced by the patient.
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14.发明授权公开(公告)号：US11648063B2
公开(公告)日：2023-05-16
申请号：US17113385
申请日：2020-12-07
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Yagna Pathak , Hyun-Joo Park , Simeng Zhang , Anahita Kyani , Erika Ross , Dehan Zhu , Douglas Lautner
IPC: A61B8/00 , A61B34/20 , G06K9/62 , G06T7/73 , A61N1/05 , G16H30/40 , G16H20/40 , G16H50/20 , G06V10/40 , A61B90/00
CPC classification number: A61B34/20 , A61N1/0534 , G06K9/6257 , G06T7/73 , G06V10/40 , G16H20/40 , G16H30/40 , G16H50/20 , A61B2034/2065 , A61B2090/374 , A61B2090/3762 , G06T2207/10064 , G06T2207/10081 , G06T2207/10088 , G06T2207/20021 , G06T2207/20081 , G06T2207/20084 , G06T2207/30016 , G06V2201/031
Abstract: The present disclosure provides systems and methods for estimating an orientation of an implanted deep brain stimulation (DBS) lead. Such methods include generating an initial image dataset, down-sampling a respective image or adding noise to images of the subset of the initial image dataset, and re-slicing at least a subset of the modified image dataset along an alternative primary imaging axis, to generate an integrated image dataset. The method also include partitioning the integrated image dataset into a preliminary training image dataset and a testing image dataset, and re-sizing at least a subset of the preliminary training image dataset with a localized field of view around a depicted DBS lead, to generate a training image dataset. The method further includes training a machine-learning model using the training image dataset, and executing the trained machine-learning model to estimate, during a DBS implantation procedure, an orientation of a subject implanted DBS lead.
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公开(公告)号：US20230056291A1
公开(公告)日：2023-02-23
申请号：US17891098
申请日：2022-08-18
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Mary Khun Hor-Lao , Binesh Balasingh , Scott DeBates , Douglas Alfred Lautner , Yagna Pathak , Simeng Zhang , Diane Whitmer , Anahita Kyani , Hyun-Joo Park , Erika Ross , David Page , Ameya Nanivadekar , Dehan Zhu
Abstract: The present disclosure is directed to providing digital health services. In some embodiments, systems and methods for conducting virtual or remote sessions between patients and clinicians are disclosed. During the sessions, media content (e.g., images, video content, audio content, etc.) may be captured as the patient performs one or more tasks. The media content may be presented to the clinician and used to evaluate a condition of the patient or a state of the condition, adjust treatment parameters, provide therapy, or other operations to treat the patient. The analysis of the media content may be aided by one or more machine learning/artificial intelligence models that analyze various aspects of the media content, augment the media content, or other functionality to aid in the treatment of the patient.
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Patent Agency Ranking
公开(公告)号：US20230055984A1
公开(公告)日：2023-02-23
申请号：US17891096
申请日：2022-08-18
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Mary Khun Hor-Lao , Binesh Balasingh , Scott DeBates , Douglas Alfred Lautner , Yagna Pathak , Simeng Zhang , Diane Whitmer , Anahita Kyani , Hyun-Joo Park , Erika Ross , David Page , Ameya Nanivadekar , Dehan Zhu
Abstract: The present disclosure is directed to providing digital health services. In some embodiments, systems and methods for conducting virtual or remote sessions between patients and clinicians are disclosed. During the sessions, media content (e.g., images, video content, audio content, etc.) may be captured as the patient performs one or more tasks. The media content may be presented to the clinician and used to evaluate a condition of the patient or a state of the condition, adjust treatment parameters, provide therapy, or other operations to treat the patient. The analysis of the media content may be aided by one or more machine learning/artificial intelligence models that analyze various aspects of the media content, augment the media content, or other functionality to aid in the treatment of the patient.
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公开(公告)号：US20230054261A1
公开(公告)日：2023-02-23
申请号：US17891102
申请日：2022-08-18
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Mary Khun Hor-Lao , Binesh Balasingh , Scott DeBates , Douglas Alfred Lautner , Yagna Pathak , Simeng Zhang , Diane Whitmer , Anahita Kyani , Hyun-Joo Park , Erika Ross , David Page , Ameya Nanivadekar , Dehan Zhu
Abstract: The present disclosure is directed to providing digital health services. In some embodiments, systems and methods for conducting virtual or remote sessions between patients and clinicians are disclosed. During the sessions, media content (e.g., images, video content, audio content, etc.) may be captured as the patient performs one or more tasks. The media content may be presented to the clinician and used to evaluate a condition of the patient or a state of the condition, adjust treatment parameters, provide therapy, or other operations to treat the patient. The analysis of the media content may be aided by one or more machine learning/artificial intelligence models that analyze various aspects of the media content, augment the media content, or other functionality to aid in the treatment of the patient.
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公开(公告)号：US20230053914A1
公开(公告)日：2023-02-23
申请号：US17891074
申请日：2022-08-18
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Mary Khun Hor-Lao , Binesh Balasingh , Scott DeBates , Douglas Alfred Lautner , Yagna Pathak , Simeng Zhang , Diane Whitmer , Anahita Kyani , Hyun-Joo Park , Erika Ross , David Page , Ameya Nanivadekar , Dehan Zhu
Abstract: The present disclosure is directed to providing digital health services. In some embodiments, systems and methods for conducting virtual or remote sessions between patients and clinicians are disclosed. During the sessions, media content (e.g., images, video content, audio content, etc.) may be captured as the patient performs one or more tasks. The media content may be presented to the clinician and used to evaluate a condition of the patient or a state of the condition, adjust treatment parameters, provide therapy, or other operations to treat the patient. The analysis of the media content may be aided by one or more machine learning/artificial intelligence models that analyze various aspects of the media content, augment the media content, or other functionality to aid in the treatment of the patient.
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19.发明申请公开(公告)号：US20220339442A1
公开(公告)日：2022-10-27
申请号：US17708724
申请日：2022-03-30
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Simeng Zhang , Hyun-Joo Park , Erika Ross
Abstract: Systems and methods which provide for and enable sensing responsive signals with respect to the application of paresthesia-free stimulation are described. Sensing signal initiators may be utilized comprising one or more non-therapeutic and/or non-tonic pulses in the form of pinging-pulses configured for invoking responsive signals suitable for measurement and/or analysis in association with the application of neural stimuli. A sensing signal initiator technique may provide an interleaved implementation to introduce one or more pinging-pulses between burst groups of a burst stimulation regimen. Additionally or alternatively, a sensing signal initiator technique may provide a postfixed implementation to introduce one or more pinging-pulses by modifying a therapeutic stimulation burst so that the last phase of the passive discharge is replaced with pinging-pulse providing an active discharge.
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公开(公告)号：US20240416128A1
公开(公告)日：2024-12-19
申请号：US18816144
申请日：2024-08-27
Applicant: Advanced Neuromodulation Systems, Inc.
Inventor： Hyun-Joo Park , Simeng Zhang , Yagna Pathak , Erika Ross
Abstract: The present disclosure provides systems and methods for generating pulsed waveforms that approximate colored noise for use in a neurostimulation system. An implantable neurostimulation system includes an implantable stimulation lead including a plurality of contacts, and an implantable pulse generator communicatively coupled to the stimulation lead. The pulse generator is configured to generate a pulsed waveform that approximates colored noise using at least one of a thresholding method and an optimization method, and cause stimulation to be delivered by the stimulation lead based on the pulsed waveform.
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