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公开(公告)号:US11779642B2
公开(公告)日:2023-10-10
申请号:US16463062
申请日:2017-12-08
Applicant: Alector LLC
Inventor: Andrew Pincetic , Arnon Rosenthal , Seung-Joo Lee
IPC: A61K39/395 , A61P31/00 , A61P35/00 , C07K16/28
CPC classification number: A61K39/39558 , A61P31/00 , A61P35/00 , C07K16/2803 , C07K2317/24 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92
Abstract: The invention provides anti-SIRPA antibodies, methods of generating such antibodies, and therapeutic uses and methods employing the antibodies.
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公开(公告)号:US11472877B2
公开(公告)日:2022-10-18
申请号:US16078965
申请日:2017-03-03
Applicant: Alector LLC
Inventor: Andrew Pincetic , Arnon Rosenthal , Helen Lam , Francesca Avogadri-Connors , Seung-Joo Lee
IPC: C07K16/28
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a TREM1 protein, e.g., a mammalian TREM1 or human TREM1, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20220289844A1
公开(公告)日:2022-09-15
申请号:US17707637
申请日:2022-03-29
Applicant: Alector LLC
Inventor: Andrew Pincetic , Wei-Hsien Ho , Patricia Culp , Arnon Rosenthal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPA polypeptide, e.g., a mammalian SIRPA or human SIRPA, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20210277113A1
公开(公告)日:2021-09-09
申请号:US17256508
申请日:2019-06-28
Applicant: Alector LLC
Inventor: Andrew Pincetic , Patricia Culp , Arnon Rosenthal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPβ1 polypeptide, e.g., a human SIRPβ1, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US20190275150A1
公开(公告)日:2019-09-12
申请号:US16463062
申请日:2017-12-08
Applicant: Alector LLC
Inventor: Andrew Pincetic , Arnon Rosenthal , Seung-Joo Lee
IPC: A61K39/395 , C07K16/28 , A61P31/00 , A61P35/00
Abstract: The invention provides anti-SIRPA antibodies, methods of generating such antibodies, and therapeutic uses and methods employing the antibodies.
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公开(公告)号:US12226482B2
公开(公告)日:2025-02-18
申请号:US18454286
申请日:2023-08-23
Applicant: Alector LLC
Inventor: Andrew Pincetic , Arnon Rosenthal , Seung-Joo Lee
IPC: A61K39/395 , A61P31/00 , A61P35/00 , C07K16/28
Abstract: The invention provides anti-SIRPA antibodies, methods of generating such antibodies, and therapeutic uses and methods employing the antibodies.
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公开(公告)号:US20230121869A1
公开(公告)日:2023-04-20
申请号:US17931757
申请日:2022-09-13
Applicant: Alector LLC
Inventor: Andrew Pincetic , Arnon Rosenthal , Helen Lam , Francesca Avogadri-Connors , Seung-Joo Lee
IPC: C07K16/28
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a TREM1 protein, e.g., a mammalian TREM1 or human TREM1, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号:US11319373B2
公开(公告)日:2022-05-03
申请号:US16421692
申请日:2019-05-24
Applicant: Alector LLC
Inventor: Andrew Pincetic , Wei-Hsien Ho , Patricia Culp , Arnon Rosenthal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPA polypeptide, e.g., a mammalian SIRPA or human SIRPA, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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