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公开(公告)号：US20250144209A1
公开(公告)日：2025-05-08
申请号：US19014653
申请日：2025-01-09
Applicant: Alector LLC
Inventor： Andrew Pincetic , Arnon Rosenthal , Seung-Joo Lee
IPC: A61K39/395 , A61P31/00 , A61P35/00 , C07K16/28
Abstract: The invention provides anti-SIRPA antibodies, methods of generating such antibodies, and therapeutic uses and methods employing the antibodies.
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公开(公告)号：US12258410B2
公开(公告)日：2025-03-25
申请号：US18627754
申请日：2024-04-05
Applicant: Alector LLC
Inventor： Andrew Pincetic , Wei-Hsien Ho , Patricia Culp , Arnon Rosenthal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPA polypeptide, e.g., a mammalian SIRPA or human SIRPA, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US12110327B2
公开(公告)日：2024-10-08
申请号：US17931757
申请日：2022-09-13
Applicant: Alector LLC
Inventor： Andrew Pincetic , Arnon Rosenthal , Helen Lam , Francesca Avogadri-Connors , Seung-Joo Lee
IPC: C07K16/28
CPC classification number: C07K16/2803 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/73 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/80 , C07K2317/92
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a TREM1 protein, e.g., a mammalian TREM1 or human TREM1, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20250026827A1
公开(公告)日：2025-01-23
申请号：US18756198
申请日：2024-06-27
Applicant: Alector LLC
Inventor： Andrew Pincetic , Patricia Culp , Arnon Rosenthal
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPβ1 polypeptide, e.g., a human SIRPβ1, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20250092131A1
公开(公告)日：2025-03-20
申请号：US18824619
申请日：2024-09-04
Applicant: Alector LLC
Inventor： Andrew Pincetic , Arnon Rosenthal , Helen Lam , Francesca Avogadri-Connors , Seung-Joo Lee
IPC: C07K16/28
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, chimeric, humanized antibodies, antibody fragments, etc., that specifically bind a TREM1 protein, e.g., a mammalian TREM1 or human TREM1, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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Patent Agency Ranking
公开(公告)号：US20240301071A1
公开(公告)日：2024-09-12
申请号：US18627754
申请日：2024-04-05
Applicant: Alector LLC
Inventor： Andrew Pincetic , Wei-Hsien Ho , Patricia Culp , Arnon Rosenthal
CPC classification number: C07K16/283 , C07K16/246 , C07K16/2818 , C07K16/2827 , C07K16/40 , C07K16/4283 , C12N15/85 , C07K2317/21 , C07K2317/24 , C07K2317/32 , C07K2317/55 , C07K2317/567 , C07K2317/622 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPA polypeptide, e.g., a mammalian SIRPA or human SIRPA, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US12060422B2
公开(公告)日：2024-08-13
申请号：US17256508
申请日：2019-06-28
Applicant: Alector LLC
Inventor： Andrew Pincetic , Patricia Culp , Arnon Rosenthal
CPC classification number: C07K16/2803 , A61P35/00 , A61K2039/505 , A61K2039/507 , C07K2317/31 , C07K2317/33 , C07K2317/75 , C07K2317/92
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPβ1 polypeptide, e.g., a human SIRPβ1, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20240270866A1
公开(公告)日：2024-08-15
申请号：US18423604
申请日：2024-01-26
Applicant: Alector LLC
Inventor： Andrew Pincetic , Arnon Rosenthal
CPC classification number: C07K16/2896 , A61P25/28 , G01N33/6854 , A61K2039/505 , C07K2317/24 , C07K2317/31 , C07K2317/56 , C07K2317/92
Abstract: The present disclosure provides antibodies and antibody fragments that bind to human SIRPA. In some embodiments, the antibodies are SIRPA agonists. The antibodies and antibody fragments disclosed herein may be used for the treatment and/or diagnosis of diseases, disorders, and conditions associated with reduced SIRPA activity.
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公开(公告)号：US11976119B2
公开(公告)日：2024-05-07
申请号：US17707637
申请日：2022-03-29
Applicant: Alector LLC
Inventor： Andrew Pincetic , Wei-Hsien Ho , Patricia Culp , Arnon Rosenthal
CPC classification number: C07K16/283 , C07K16/246 , C07K16/2818 , C07K16/2827 , C07K16/40 , C07K16/4283 , C12N15/85 , C07K2317/21 , C07K2317/24 , C07K2317/32 , C07K2317/55 , C07K2317/567 , C07K2317/622 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/92
Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal, antibodies, antibody fragments, etc., that specifically bind a SIRPA polypeptide, e.g., a mammalian SIRPA or human SIRPA, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.
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公开(公告)号：US20240082395A1
公开(公告)日：2024-03-14
申请号：US18454286
申请日：2023-08-23
Applicant: Alector LLC
Inventor： Andrew Pincetic , Arnon Rosenthal , Seung-Joo Lee
IPC: A61K39/395 , A61P31/00 , A61P35/00 , C07K16/28
CPC classification number: A61K39/39558 , A61P31/00 , A61P35/00 , C07K16/2803 , C07K2317/24 , C07K2317/732 , C07K2317/75 , C07K2317/76 , C07K2317/77 , C07K2317/92
Abstract: The invention provides anti-SIRPA antibodies, methods of generating such antibodies, and therapeutic uses and methods employing the antibodies.
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