利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

97 条记录 (耗时 0.033 秒)

    METHOD AND APPARATUS FOR SAFE AND EFFICIENT DELIVERY OF CARDIAC STRESS AUGMENTATION PACING
    16.
    发明申请
    METHOD AND APPARATUS FOR SAFE AND EFFICIENT DELIVERY OF CARDIAC STRESS AUGMENTATION PACING 有权
    安全有效地提供CARDIAC应力补充剂的方法和装置

    公开(公告)号：US20100305648A1

    公开(公告)日：2010-12-02

    申请号：US12770351

    申请日：2010-04-29

    申请人： Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Craig Stolen ,  Robert Shipley

    发明人： Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  Craig Stolen ,  Robert Shipley

    IPC分类号： A61N1/365 ,  A61N1/362

    CPC分类号： A61N1/3627 ,  A61N1/37

    摘要： A cardiac pacing system controls the progression of a cardiac disorder such as heart failure by delivering cardiac stress augmentation pacing to create or augment regional stress in the heart according to a delivery schedule programmed for a patient. Various events associated with the patient's conditions, activities, and other treatments may render the cardiac stress augmentation pacing risky or ineffective. The system detects such events before and during each cardiac stress augmentation pacing session and modifies the delivery schedule in response to the detection of each event to ensure patient safety and therapy efficiency.

    摘要翻译： 心脏起搏系统通过递送心脏应力增加起搏来控制心脏疾病例如心力衰竭的进展，以根据为患者编程的递送计划创建或增加心脏中的区域应力。 与患者病情，活动和其他治疗相关的各种事件可能使心脏应激增加起搏风险或无效。 该系统在每个心脏应激增强起搏会话之前和期间检测这些事件，并根据每个事件的检测来修改递送计划，以确保患者的安全性和治疗效率。

    TITRATED INTERMITTENT PACING THERAPY
    18.
    发明申请
    TITRATED INTERMITTENT PACING THERAPY 有权
    治疗间歇性间歇性治疗

    公开(公告)号：US20100087887A1

    公开(公告)日：2010-04-08

    申请号：US12573533

    申请日：2009-10-05

    申请人： Yanting Dong ,  Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  David L. Whitehouse

    发明人： Yanting Dong ,  Shantha Arcot-Krishnamurthy ,  Allan C. Shuros ,  David L. Whitehouse

    IPC分类号： A61N1/365

    CPC分类号： A61N1/3627 ,  A61N1/3682 ,  A61N1/3688

    摘要： Cardioprotective pre-excitation pacing may be applied to stress or de-stress a particular myocardial region delivering of pacing pulses in a manner that causes a dyssynchronous contraction. Such dyssynchronous contractions are responsible for the desired cardioprotective effects of pre-excitation pacing but may also be hazardous. Described herein is a method and system that uses measures of a patient's heart rate or exertion level to control the duty cycles of intermittent pre-excitation pacing.

    摘要翻译： 心脏保护性预激发起搏可用于以导致同步收缩的方式对起搏脉冲递送的特定心肌区域应力或去应激。 这种异常收缩负责预激励起搏的所需心脏保护作用，但也可能是危险的。 这里描述了一种方法和系统，其使用患者心率或运动水平的测量来控制间歇性预激发起搏的占空比。

    APPARATUS AND METHODS FOR TREATMENT OF ATHEROSCLEROSIS AND INFARCTION
    19.
    发明申请
    APPARATUS AND METHODS FOR TREATMENT OF ATHEROSCLEROSIS AND INFARCTION 审中-公开
    用于治疗角膜移植和感染的装置和方法

    公开(公告)号：US20100016916A1

    公开(公告)日：2010-01-21

    申请号：US12504593

    申请日：2009-07-16

    申请人： Shantha Arcot-Krishnamurthy ,  Joseph M. Pastore ,  Allan C. Shuros ,  Scott A. Meyer ,  Robert Shipley ,  Jason J. Hamann

    发明人： Shantha Arcot-Krishnamurthy ,  Joseph M. Pastore ,  Allan C. Shuros ,  Scott A. Meyer ,  Robert Shipley ,  Jason J. Hamann

    IPC分类号： A61N1/368

    CPC分类号： A61N1/36564 ,  A61N1/36528 ,  A61N1/36571 ,  A61N1/368

    摘要： A pacing system delivers cardiac protective pacing therapy (CPPT) to protect the heart from injuries and/or to treat existing injuries. The pacing system receives a set of inputs and delivers optimized cardiac protection pacing tailored for different purposes. The system delivers electrical stimulation to modulate myocardial strain for anti-atherosclerosis therapy and/or to provide therapy for myocardial infarction (MI). In one embodiment, a medical device for treating atherosclerosis is provided. The medical device includes a sensing circuit to receive sensed signals to identify areas of coronary artery disease (CAD) or areas at risk for CAD using the sensed signals. The device also includes a pacemaker circuit adapted to deliver an electrical signal through at least one electrode to a myocardial target adjacent to the identified areas. According to various embodiments, a controller communicates with the sensing circuit and controls the pacemaker circuit to provide intermittent electrical stimulation to the myocardial target to induce periods of stretch on the vessel due to induce myocardial strain changes. The stimulation is targeted to attenuate or prevent atherosclerosis associated with the CAD, according to various embodiments.

    摘要翻译： 起搏系统提供心脏保护起搏治疗（CPPT），以保护心脏免受伤害和/或治疗现有的伤害。 起搏系统接收一组输入，并为不同目的提供优化的心脏保护起搏。 该系统提供电刺激以调节用于抗动脉粥样硬化治疗的心肌应变和/或提供心肌梗塞（MI）治疗。 在一个实施方案中，提供了用于治疗动脉粥样硬化的医疗装置。 医疗设备包括感测电路，用于接收感测到的信号，以使用感测到的信号来识别冠状动脉疾病（CAD）或CAD风险区域。 该装置还包括起搏器电路，其适于将电信号通过至少一个电极传递到与所识别的区域相邻的心肌靶。 根据各种实施例，控制器与感测电路通信并控制起搏器电路，以向心肌靶标提供间歇性电刺激，以诱导由于诱发心肌应变变化而在血管上延伸的时间段。 根据各种实施方案，刺激旨在减弱或预防与CAD相关的动脉粥样硬化。

    CONFIGURABLE INTERMITTENT PACING THERAPY
    20.
    发明申请
    CONFIGURABLE INTERMITTENT PACING THERAPY 失效
    配置间歇性治疗

    公开(公告)号：US20090192560A1

    公开(公告)日：2009-07-30

    申请号：US12361353

    申请日：2009-01-28

    申请人： Shantha Arcot-Krishnamurthy ,  John R. Zielinski ,  Joseph M. Pastore ,  Jeffrey E. Stahmann ,  Allan C. Shuros ,  Robert Shipley

    发明人： Shantha Arcot-Krishnamurthy ,  John R. Zielinski ,  Joseph M. Pastore ,  Jeffrey E. Stahmann ,  Allan C. Shuros ,  Robert Shipley

    IPC分类号： A61N1/365

    CPC分类号： A61N1/3627 ,  A61N1/3688

    摘要： This document discusses, among other things, an apparatus comprising at least one implantable cardiac depolarization sensing circuit, an electrical stimulation circuit, and a pacing mode controller. The implantable cardiac depolarization sensing circuit is configured to obtain a sensed depolarization signal from a ventricle and the electrical stimulation circuit is configured to provide pacing electrical stimulation energy to at least one implantable ventricular electrode. The pacing mode controller delivers pacing therapy according to a first pacing mode that is a normal operating mode, and delivers pacing therapy according to second and third pacing modes. The second and third pacing modes increase mechanical stress on at least a particular portion of the ventricle as compared to the pacing therapy delivered during the first pacing mode. The pacing mode controller alternates between the second and third pacing modes when switched from the normal operating mode to a stress augmentation mode.

    摘要翻译： 本文件尤其涉及包括至少一个可植入心脏去极化感测电路，电刺激电路和起搏模式控制器的装置。 可植入心脏去极化感测电路被配置为从心室获得感测的去极化信号，并且电刺激电路被配置为向至少一个可植入心室电极提供起搏电刺激能量。 起搏模式控制器按照正常运行模式的第一起搏模式提供起搏治疗，并根据第二和第三起搏模式提供起搏治疗。 与在第一起搏模式期间递送的起搏治疗相比，第二和第三起搏模式增加至少在心室的特定部分上的机械应力。 当从正常操作模式切换到应力增强模式时，起搏模式控制器在第二和第三起搏模式之间交替。