公开(公告)号：US20170340782A1

公开(公告)日：2017-11-30

申请号：US15679756

申请日：2017-08-17

Applicant: BOSTON SCIENTIFIC SCIMED, INC.

Inventor： SEAN P. FLEURY ,  MARK D. WOOD ,  DANE T. SEDDON ,  LAURA ELIZABETH FIRSTENBERG ,  PAUL SMITH ,  GARY J. LEANNA ,  CLAUDE O. CLERC ,  JAMES WELDON ,  STEVEN E. WALAK

IPC: A61L31/14 ,  A61F2/82 ,  A61L31/10 ,  A61F2/07 ,  A61F2/00 ,  A61F2/86 ,  A61F2/04

CPC classification number: A61L31/14 ,  A61F2/0077 ,  A61F2/07 ,  A61F2/82 ,  A61F2/86 ,  A61F2002/043 ,  A61F2230/0067 ,  A61F2230/0091 ,  A61F2250/0026 ,  A61F2250/0039 ,  A61F2250/0051 ,  A61F2250/0056 ,  A61L31/10 ,  A61L2400/12 ,  A61L2400/18 ,  C08L27/18 ,  C08L23/12

Abstract: A method for reducing mucus accumulation in an airway including disposing an implantable device within an airway, wherein the implantable device has a first end, a second end, and an inner surface defining a lumen extending from the first end to the second end; wherein at least a portion of the inner surface has a hydrophobic polymer coating thereon, wherein a polymer coating surface has dynamic water contact angles of 145 degrees or greater; and wherein the implantable device is constructed and arranged to maintain patency of the airway; wherein accumulation of mucus is reduced as compared to a similar implantable device without the hydrophobic portion of the inner surface. An implantable medical device having a superhydrophobic surface and a method of making an implantable medical device having a superhydrophobic surface are also provided. An implantable medical device having a micropatterned surface with enhanced adhesion to tissue, optionally in combination with other region(s) having a superhydrophobic surface and a method of making such a device. Methods and devices for prevention of bacterial adhesion to implanted medical devices.