公开(公告)号：US10179190B2

公开(公告)日：2019-01-15

申请号：US15167209

申请日：2016-05-27

Applicant: Boston Scientific Scimed, Inc.

Inventor： Sandra Nagale ,  David Shreeve ,  Mark Boden ,  Jonathan Zoll ,  Timothy Harrah ,  Steven Kangas ,  Kasyap Seethamraju ,  Deanna Cavallaro ,  Martin Phelan

IPC: A61L27/20 ,  A61L27/52

Abstract: Methods of treating tissue of a patient, e.g., tissue of an organ such that the bladder, are described. The methods may comprise inserting a medical device within the bladder; and injecting a composition to separate a first layer of tissue from a second layer of tissue. The composition may comprise at least one polysaccharide compound having a concentration ranging from approximately 0.05% to approximately 25% by weight, with respect to the total weight of the composition. The composition may at least partially separate the first layer of tissue from the second layer of tissue. At least one of the first layer of tissue or the second layer of tissue may be a detrusor muscle tissue.

公开(公告)号：US09370645B2

公开(公告)日：2016-06-21

申请号：US14211838

申请日：2014-03-14

Applicant: Boston Scientific Scimed, Inc.

Inventor： James Rohl ,  Mary Byron ,  Joel Eggert ,  Sandra Nagale ,  Mark Boden ,  David Lehse

IPC: A61M29/00 ,  A61M25/10 ,  A61M37/00

CPC classification number: A61M25/1011 ,  A61M2025/1013 ,  A61M2025/105 ,  A61M2037/0023

Abstract: A medical device including an outer balloon, an inner balloon, and at least one delivery unit is disclosed. The outer balloon defines a first internal cavity that remains in fluid communication with a first inflation lumen. The inner balloon is disposed within the first internal cavity, and defines a second internal cavity that is in fluid communication with a second inflation lumen. Each delivery unit includes at least one needle configured to pierce a tissue and at least one reservoir containing a material. Further, inflation of the outer balloon or the inner balloon is structured and arranged to deliver the material into the tissue through the needle lumen.

Abstract translation: 公开了一种包括外球囊，内球囊和至少一个输送单元的医疗装置。 外球囊限定与第一充气腔保持流体连通的第一内腔。 内气球设置在第一内腔内，并且限定与第二充气腔流体连通的第二内腔。 每个递送单元包括构造成刺穿组织的至少一个针和至少一个包含材料的贮存器。 此外，外球囊或内气球的膨胀被构造和布置成通过针管内腔将材料输送到组织中。

公开(公告)号：US20170035341A1

公开(公告)日：2017-02-09

申请号：US15228552

申请日：2016-08-04

Applicant: Boston Scientific Scimed, Inc.

Inventor： Sandra Nagale ,  Shibaji Shome ,  Timothy Harrah ,  Mark Boden ,  Allan Shuros ,  Bryan Clark ,  Amedeo Chiavetta ,  Lynne Swanson ,  Dennis Werner

IPC: A61B5/20 ,  A61B1/07 ,  A61B1/04 ,  A61B18/14 ,  A61B1/00 ,  A61B5/0488 ,  A61N1/36 ,  A61B5/00 ,  A61B1/307

Abstract: Systems, devices and methods for the treatment of bladder conditions using bladder visualization without the need for optical elements and for subsequent direct electrical pacing are provided. The systems, devices and methods generally apply pacing stimulus directly to the bladder wall, from one or more of the inner and outer bladder surfaces.

Abstract translation: 提供了使用膀胱可视化治疗膀胱状况的系统，装置和方法，而不需要光学元件和随后的直接起搏。 系统，装置和方法通常将起搏刺激直接从膀胱壁的一个或多个施加到膀胱壁上。

公开(公告)号：US20140018440A1

公开(公告)日：2014-01-16

申请号：US14030461

申请日：2013-09-18

Applicant: Boston Scientific Scimed, Inc.

Inventor： Mark Boden

IPC: A61K47/32 ,  A61K47/34

CPC classification number: A61K47/32 ,  A61K47/34 ,  A61L27/34 ,  A61L27/54 ,  A61L29/085 ,  A61L29/16 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/00 ,  C08L101/005

Abstract: According to an aspect of the present invention, internal medical devices are provided, which contain at least one surface region that comprises a polymer brush. The polymer brush, in turn, contains one or more types of hydrophobic polymer chains and one or more types of hydrophilic polymer chains.

Abstract translation: 根据本发明的一个方面，提供内部医疗装置，其包含至少一个包括聚合物刷的表面区域。 聚合物刷又依次含有一种或多种类型的疏水性聚合物链和一种或多种类型的亲水性聚合物链。