公开(公告)号：US10959936B2

公开(公告)日：2021-03-30

申请号：US16934596

申请日：2020-07-21

Applicant: Colgate-Palmolive Company

Inventor： Lynette A. Zaidel ,  Guisheng Pan ,  Suman K. Chopra ,  Prakasarao Mandadi ,  Michael Prencipe

IPC: A61K8/22 ,  A61K8/81 ,  A61K8/02 ,  A61Q11/00 ,  A61Q11/02 ,  A61K8/24 ,  A61K8/90 ,  A61K8/49 ,  A61K8/891

Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

公开(公告)号：US09901521B2

公开(公告)日：2018-02-27

申请号：US15106920

申请日：2013-12-23

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Venda Porter-Maloney ,  Suman K. Chopra ,  Dennis Ontumi

IPC: A61K8/22 ,  A61K8/81 ,  A61Q11/02 ,  A61K8/49 ,  A61Q11/00

CPC classification number: A61K8/22 ,  A61K8/492 ,  A61K8/8176 ,  A61K2800/43 ,  A61Q11/00 ,  A61Q11/02

Abstract: Described herein are oral care compositions comprising a crosslinked polyvinylpyrrolidone complexed with hydrogen peroxide, together with a blue to violet-blue pigment; including some embodiments which further comprise an ethylene oxide, propylene oxide block co-polymer.

公开(公告)号：US09895304B2

公开(公告)日：2018-02-20

申请号：US15344504

申请日：2016-11-04

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Lynette A. Zaidel ,  Guisheng Pan ,  Suman K. Chopra ,  Prakasarao Mandadi ,  Michael Prencipe

IPC: A61Q11/02 ,  A61K8/81 ,  A61K8/02 ,  A61K8/22 ,  A61Q11/00 ,  A61K8/24 ,  A61K8/90 ,  A61K8/49 ,  A61K8/891

CPC classification number: A61K8/8176 ,  A61K8/0208 ,  A61K8/22 ,  A61K8/24 ,  A61K8/49 ,  A61K8/817 ,  A61K8/891 ,  A61K8/90 ,  A61K2800/805 ,  A61Q11/00 ,  A61Q11/02

Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

公开(公告)号：US20170105922A1

公开(公告)日：2017-04-20

申请号：US15390814

申请日：2016-12-27

Applicant: Colgate-Palmolive Company

Inventor： Michael Prencipe ,  Suman K. Chopra ,  Michael Collins

IPC: A61K8/89 ,  A61Q11/00 ,  A61C19/06 ,  A61K8/22

CPC classification number: A61K8/89 ,  A61C19/066 ,  A61K8/22 ,  A61K8/8176 ,  A61K8/891 ,  A61K8/895 ,  A61Q11/00

Abstract: A tooth whitening system comprising a dental tray having a surface operable to confront a tooth surface, and a tooth whitening composition comprising a whitening agent and a hydrophobic. polymer carrier. The tooth whitening composition is preferably substantially non-water soluble. A tooth whitening kit is also provided using a dental tray and the tooth whitening composition comprising a whitening composition and a hydrophobic polymer carrier.

公开(公告)号：US09517194B2

公开(公告)日：2016-12-13

申请号：US14723139

申请日：2015-05-27

Applicant: Colgate-Palmolive Company

Inventor： Lynette A. Zaidel ,  Guisheng Pan ,  Suman K. Chopra ,  Prakasarao Mandadi ,  Michael Prencipe

IPC: A61Q11/02 ,  A61K8/81 ,  A61K8/02 ,  A61K8/22 ,  A61Q11/00 ,  A61K8/24 ,  A61K8/90

CPC classification number: A61K8/8176 ,  A61K8/0208 ,  A61K8/22 ,  A61K8/24 ,  A61K8/49 ,  A61K8/817 ,  A61K8/891 ,  A61K8/90 ,  A61K2800/805 ,  A61Q11/00 ,  A61Q11/02

Abstract: Oral care compositions comprising: (a) a peroxide complex comprising a peroxide component and an N-vinyl heterocyclic polymer (e.g., poly-N-vinyl polylactam, or poly-N-vinyl-polyimide); (b) a whitening agent (e.g., hydrogen peroxide); and (c) an orally acceptable carrier. In one embodiment, the carrier comprises a film forming material. Methods are also provided for making an oral care composition comprising: (a) mixing a whitening agent, silicone adhesive and carrier fluid to form a homogenous mixture; (b) adding a peroxide complex to said homogenous mixture, wherein said complex comprises hydrogen peroxide and an N-vinyl heterocyclic polymer; and (c) mixing under vacuum.

公开(公告)号：US20130259811A1

公开(公告)日：2013-10-03

申请号：US13897817

申请日：2013-05-20

Applicant: COLGATE-PALMOLIVE COMPANY

Inventor： Michael Prencipe ,  Suman K. Chopra ,  Michael Collins

IPC: A61C19/06 ,  A61K8/22 ,  A61Q11/00 ,  A61K8/18

CPC classification number: A61C19/066 ,  A61K8/18 ,  A61K8/22 ,  A61K8/8176 ,  A61K8/891 ,  A61Q11/00

Abstract: A dental tray with a hydrophobic tooth whitening formulation where the tooth whitening formulation is substantially non-water soluble, and a method of using this dental tray to whiten the teeth. The tooth whitening formulation is primarily comprised of a hydrophobic polymer and a peroxide or a peroxide yielding compound. Preferably the hydrophobic polymer is the condensation product of a silicone resin and an organosiloxane. The dental tray is formed to encompass the front and the rear surfaces of the teeth. The dental tray is comprised of a thermoplastic or thermoset polymer. The teeth whitening formulation is placed into the dental tray and the tray placed against the teeth to be whitened. This is for a sufficient period of time to at least partially whiten teeth. This can be a period of time from about 0.5 hour to 2 hours or more. The substantially non-aqueous tooth whitening formulation is effective over a longer period of time since it is not significantly diluted or removed from the dental tray during the treatment time.

Abstract translation: 具有疏水牙齿美白配方的牙科托盘，其中牙齿美白配方基本上是非水溶性的，以及使用该牙科托盘来使牙齿变白的方法。 牙齿美白制剂主要由疏水性聚合物和过氧化物或产生过氧化物的化合物组成。 优选地，疏水性聚合物是有机硅树脂和有机硅氧烷的缩合产物。 牙托被形成为包围牙齿的前表面和后表面。 牙科托盘由热塑性或热固性聚合物组成。 将牙齿美白配制剂放入牙托中，并将放置在牙齿上的托盘白化。 这是足够的时间来至少部分地美白牙齿。 这可以是约0.5小时至2小时或更长时间。 基本上非水性牙齿美白制剂在较长时间内是有效的，因为在治疗时间内没有显着稀释或从牙盘中除去。