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公开(公告)号:US20120238585A1
公开(公告)日:2012-09-20
申请号:US13427644
申请日:2012-03-22
IPC分类号: C07C57/42 , C07C229/66 , A61K31/196 , A61P29/00 , A61K31/166 , C07D295/192 , A61K31/495 , A61K31/235 , C07C229/42
CPC分类号: A61K31/609 , A61K31/60 , C07C69/86 , C07C69/94 , C07C233/18 , C07C233/49 , C07C233/55 , C07C235/52 , C07C235/60 , C07C237/22 , C07C271/28 , C07C275/42 , C07D295/182 , C07D295/192
摘要: The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a Fatty Acid Acetylated Salicylate Derivative.
摘要翻译: 本发明涉及脂肪酸乙酰化水杨酸衍生物; 包含有效量的脂肪酸乙酰化水杨酸衍生物的组合物; 以及用于治疗或预防炎症性疾病的方法,包括施用有效量的脂肪酸乙酰化水杨酸衍生物。
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公开(公告)号:US20120238530A1
公开(公告)日:2012-09-20
申请号:US13427639
申请日:2012-03-22
IPC分类号: A61K31/609 , A61P3/00 , A61P3/10 , A61P9/06 , A61P9/00 , A61P13/12 , A61P9/10 , A61P25/00 , A61P3/06 , A61P27/02 , A61P1/00 , A61P1/04 , A61P25/28 , A61P31/00 , A61P25/16 , A61P21/00 , A61K31/618 , A61P29/00
CPC分类号: A61K31/609 , A61K31/60 , C07C69/86 , C07C69/94 , C07C233/18 , C07C233/49 , C07C233/55 , C07C235/52 , C07C235/60 , C07C237/22 , C07C271/28 , C07C275/42 , C07D295/182 , C07D295/192
摘要: The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a Fatty Acid Acetylated Salicylate Derivative.
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公开(公告)号:US20100041748A1
公开(公告)日:2010-02-18
申请号:US12499779
申请日:2009-07-08
IPC分类号: A61K31/27 , A61K31/225 , A61K31/20 , C07C261/00 , C07C69/34 , C07C229/00
CPC分类号: A61K31/609 , A61K31/60 , C07C69/86 , C07C69/94 , C07C233/18 , C07C233/49 , C07C233/55 , C07C235/52 , C07C235/60 , C07C237/22 , C07C271/28 , C07C275/42 , C07D295/182 , C07D295/192
摘要: The invention relates to Fatty Acid Acetylated Salicylate Derivatives; compositions comprising an effective amount of a Fatty Acid Acetylated Salicylate Derivative; and methods for treating or preventing an inflammatory disorder comprising the administration of an effective amount of a Fatty Acid Acetylated Salicylate Derivative.
摘要翻译: 本发明涉及脂肪酸乙酰化水杨酸衍生物; 包含有效量的脂肪酸乙酰化水杨酸衍生物的组合物; 以及用于治疗或预防炎症性疾病的方法,包括施用有效量的脂肪酸乙酰化水杨酸衍生物。
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公开(公告)号:US3959057A
公开(公告)日:1976-05-25
申请号:US565691
申请日:1975-04-07
申请人: Jesse J. Smith
发明人: Jesse J. Smith
CPC分类号: B29C47/0033 , B29C47/24 , B29C47/30 , B29C47/0014 , B29L2028/00
摘要: A means and method for producing plastic netting wherein a hot pneumatic fluid such as nitrogen is used to blow filaments of one circular row of plastic filaments into contact with another circular row of plastic filaments which rows are concentric with each other and being rotated in opposite directions by a respective pair of counter-rotating dies. The hot pneumatic fluid is preferably an inert gas such as nitrogen and serves to anneal the plastic at the weld intersections of the filaments as well as to prevent oxidation during the period when the filaments are quite hot. The means disclosed herein comprises a pair of concentric relatively rotatable dies each having a circular row of plastic extrusion orifices, the dies being adapted to rotate in opposite directions and the rows of orifices being in close proximity to each other and means for projecting hot pneumatic fluid is carried by one of the dies and the hot pneumatic fluid is directed to filaments extruded from a circular row of orifices of the same die which carries the means for projecting the hot pneumatic fluid toward the extruded plastic filaments. Additionally, the individual plastic extrusion orifices are generally aligned axially with individual jet openings through which the hot pneumatic fluid is directed laterally against the filaments of one of said circular rows so that such filaments are blown into weld contact with the plastic filaments extruded from the other circular row of extrusion orifices carried by the other die.
摘要翻译: 一种用于生产塑料网的方法和方法,其中使用诸如氮气的热气动流体来吹塑一根圆形的塑料丝的长丝与另一个圆形排的塑料细丝接触,这些列彼此同心并以相反方向旋转 通过相应的一对反向旋转模具。 热气动流体优选为惰性气体如氮气,用于在长丝的焊接交叉处对塑料进行退火以及在长丝相当热的时期期间防止氧化。 本文公开的装置包括一对同心相对旋转的模具,每个模具均具有圆形排的塑料挤出孔,该模具适于沿相反方向旋转,并且该排排彼此紧邻,并且用于将热气动流体 由一个模具承载,并且热气动流体被引导到从相同模具的圆形排的孔排出的细丝,其携带用于将热气动流体投射到挤出的塑料细丝的装置。 另外,单个塑料挤出孔通常与各个喷射开口轴向对准,热气动流体通过该喷射开口横向对着所述圆形排中的一个的长丝定向,使得这种细丝被吹塑成与从另一个挤出的塑料细丝焊接接触 另一个模具承载的圆形排挤压孔。
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公开(公告)号:US20110097423A1
公开(公告)日:2011-04-28
申请号:US12909620
申请日:2010-10-21
申请人: R. Daniel Beauchamp , Jesse J. Smith , Aixiang Jiang , Yu Shyr , Bing Zhang , Natasha G. Deane
发明人: R. Daniel Beauchamp , Jesse J. Smith , Aixiang Jiang , Yu Shyr , Bing Zhang , Natasha G. Deane
CPC分类号: G01N33/57419 , C12Q1/6886 , C12Q2600/118 , C12Q2600/156 , G01N33/57484
摘要: The present invention is drawn to methods of assessing colorectal cancer prognosis by examining the expression of particular genes disregulated in this disease state. Subjects exhibiting disregulation in one or more of these genes will have a higher risk of cancer recurrence and death.
摘要翻译: 本发明涉及通过检查在该疾病状态中失调的特定基因的表达来评估结肠直肠癌预后的方法。 在一种或多种这些基因中显示失调的受试者将具有更高的癌症复发和死亡风险。
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